Patents by Inventor Pamela K. Woodard

Pamela K. Woodard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imaging agents and uses thereof
    Patent number: 11207433
    Abstract: The present invention relates to various compositions and methods of using these compositions for imaging natriuretic peptide receptors using, for example, positron emission tomography.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: December 28, 2021
    Assignee: Washington University
    Inventors: Yongjian Liu, Pamela K. Woodard
  • NONINVASIVE IMAGING OF FOCAL ATHEROSCLEROTIC LESIONS USING FLUORESCENCE MOLECULAR TOMOGRAPHY
    Publication number: 20200330615
    Abstract: The present disclosure provides compositions comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO:1), and a detectable label. Further disclosed are methods of imaging atherosclerotic plaque by optical imaging using a peptide composition.
    Type: Application
    Filed: July 2, 2020
    Publication date: October 22, 2020
    Inventors: Pamela K. Woodard, Monica Shokeen, Samuel Achilefu
  • IMAGING AGENTS AND USES THEREOF
    Publication number: 20190388570
    Abstract: The present invention relates to various compositions and methods of using these compositions for imaging natriuretic peptide receptors using, for example, positron emission tomography.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: Washington University
    Inventors: Yongjian Liu, Pamela K. Woodard
  • NONINVASIVE IMAGING OF FOCAL ATHEROSCLEROTIC LESIONS USING FLUORESCENCE MOLECULAR TOMOGRAPHY
    Publication number: 20170095577
    Abstract: The present disclosure provides compositions comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO:1), and a detectable label. Further disclosed are methods of imaging atherosclerotic plaque by optical imaging using a peptide composition.
    Type: Application
    Filed: October 6, 2016
    Publication date: April 6, 2017
    Inventors: Pamela K. Woodard, Monica Shokeen, Samuel Achilefu
  • Natriuretic peptide-mediated imaging of atherosclerotic plaque
    Patent number: 8436140
    Abstract: Tracers comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO.: 1), and a signaling moiety, are disclosed. Further disclosed are methods of imaging atherosclerotic plaque by PET scanning or MRI using a tracer.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: May 7, 2013
    Assignee: Washington University
    Inventors: Pamela K. Woodard, Michael J. Welch, Geoffrey E. Woodard, Rafaella Rossin
  • TARGETING NPR-C IN ANGIOGENESIS AND ATHEROSCLEROSIS WITH A C-TYPE ATRIAL NATRIURETIC FACTOR (CANF)-COMB NANOCOMPLEX
    Publication number: 20110300071
    Abstract: Tracers are disclosed comprising an amphiphilic comb-like nanostructure conjugated with an oligopeptide such as a fragment of a natriuretic peptide, and a signaling moiety such as a positron-emitting radionuclide. A fragment of a natriuretic peptide comprises Arg-Ile-Asp-Arg-Ile (SEQ ID NO:1). Further disclosed are methods of imaging distribution of C-type atrial natriuretic peptide receptors and methods of imaging angiogenesis and atherosclerosis by PET scanning or MRI using a tracer.
    Type: Application
    Filed: June 3, 2011
    Publication date: December 8, 2011
    Applicant: Washington University
    Inventors: Pamela K. WOODARD, Yongjian LIU, Eric PRESSLY, Dana ABENDSCHEIN, Craig J. HAWKER, Michael J. WELCH
  • Natriuretic peptide-mediated imaging of atherosclerotic plaque
    Publication number: 20100021381
    Abstract: Tracers comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO.: 1), and a signaling moiety, are disclosed. Further disclosed are methods of imaging atherosclerotic plaque by PET scanning or MRI using a tracer.
    Type: Application
    Filed: May 22, 2009
    Publication date: January 28, 2010
    Applicant: Washington University
    Inventors: Pamela K. Woodard, Michael J. Welch, Geoffrey E. Woodard, Rafaella Rossin