Patents by Inventor Pamela Kelley
Pamela Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9926368Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: January 22, 2015Date of Patent: March 27, 2018Assignee: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Publication number: 20150152176Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: January 22, 2015Publication date: June 4, 2015Inventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Patent number: 8956608Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: June 5, 2013Date of Patent: February 17, 2015Assignee: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Publication number: 20140086920Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: June 5, 2013Publication date: March 27, 2014Inventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Patent number: 8590077Abstract: A hands-free emergency all terrain light-weight litter, having: a panel having a leg support portion, a body support portion and a head support portion; a pair of parallel longitudinal support straps running along the length of the panel, and extending from opposite ends of the panel; and a plurality of interlocking patient stabilization straps extending from the body support portion of the panel, wherein the interlocking patient stabilization straps are dimensioned to pass over a patient's upper body, and lock together over the front of the patient's upper body.Type: GrantFiled: January 18, 2011Date of Patent: November 26, 2013Inventors: Ryan Warwick Saunders, Pamela Kelley Saunders, Cindy Richardson Saunders
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Patent number: 8496934Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: December 4, 2012Date of Patent: July 30, 2013Assignee: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Patent number: 8349327Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: February 18, 2011Date of Patent: January 8, 2013Assignee: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, William Kelley, legal representative, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Publication number: 20120016106Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: March 2, 2011Publication date: January 19, 2012Applicant: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Erika L.F. Holzbaur-Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, William Kelley, Xiang-Yang Tan, Seung Poon Kwak, Karen Wallace, Nicholas Weber, Menelas N. Pangalos
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Publication number: 20120003212Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: February 18, 2011Publication date: January 5, 2012Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, WYETH LLCInventors: FRANK S. WALSH, MARGARET M. ZALESKA, DAVID S. HOWLAND, ERIKA L.F. HOLZBAUR-HOWLAND, LIOUDMILA TCHISTIAKOVA, RIYEZ KARIM, PAMELA KELLEY, XIANG-YANG TAN, SEUNG POON KWAK, KAREN WALLACE, NICHOLAS WEBER, MENELAS N. PANGALOS, WILLIAM KELLEY
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Publication number: 20110220695Abstract: A hands-free emergency all terrain light-weight litter, having: a panel having a leg support portion, a body support portion and a head support portion; a pair of parallel longitudinal support straps running along the length of the panel, and extending from opposite ends of the panel; and a plurality of interlocking patient stabilization straps extending from the body support portion of the panel, wherein the interlocking patient stabilization straps are dimensioned to pass over a patient's upper body, and lock together over the front of the patient's upper body.Type: ApplicationFiled: January 18, 2011Publication date: September 15, 2011Inventors: Ryan Warwick Saunders, Pamela Kelley Saunders, Cindy Richardson Saunders
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Patent number: 7910107Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: July 24, 2009Date of Patent: March 22, 2011Assignees: WYETH LLC, The Trustees of the University of PennsylvaniaInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Erika L. F. Holzbaur-Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, William Kelley, legal representative, Xiang-Yang Tan, Seung Poon Kwak, Karen Wallace, Nicholas Weber, Menelas N. Pangalos
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Patent number: 7888486Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: GrantFiled: August 14, 2006Date of Patent: February 15, 2011Assignee: Wyeth LLCInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, William Kelley, legal representative, Xiang-Yang Tan, Seung Poon Kwak, Menelas N. Pangalos
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Publication number: 20090285827Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: July 24, 2009Publication date: November 19, 2009Applicants: Wyeth, The Trustees of the University of PennsylvaniaInventors: Frank S. Walsh, Margaret M. Zaleska, David S. Howland, Erika L. F. Holzbaur-Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, William Kelley, Xiang-Yang Tan, Seung Poon Kwak, Karen Wallace, Nicholas Weber, Menelas N. Pangalos
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Publication number: 20070087000Abstract: The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.Type: ApplicationFiled: August 14, 2006Publication date: April 19, 2007Inventors: Frank Walsh, Margaret Zaleska, David Howland, Erika Holzbaur-Howland, Lioudmila Tchistiakova, Riyez Karim, Pamela Kelley, Xiang-Yang Tan, Seung Kwak, Karen Wallace, Nicholas Weber, Menelas Pangalos, William Kelley