Patents by Inventor Pamela Loreen Rossman

Pamela Loreen Rossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120184542
    Abstract: Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer, Down syndrome or early onset Alzheimer's disease.
    Type: Application
    Filed: January 12, 2012
    Publication date: July 19, 2012
    Inventors: Kevin Anderson, Yi Chen, Zhi Chen, Kin-Chun Luk, Pamela Loreen Rossman, Hongmao Sun, Peter Michael Wovkulich
  • Publication number: 20120184548
    Abstract: Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 19, 2012
    Inventors: Romyr Dominique, Kin-Chun Luk, Qi Qiao, Pamela Loreen Rossman
  • Patent number: 7932390
    Abstract: There are provided compounds of the formula wherein R1, R2, R3, X, ring A and ring B are as described. The compounds exhibit anticancer properties.
    Type: Grant
    Filed: June 18, 2007
    Date of Patent: April 26, 2011
    Assignee: Hoffman-La Roche Inc.
    Inventors: Yi Chen, Kin-Chun Luk, Pamela Loreen Rossman, Sung-Sau So
  • Publication number: 20110071147
    Abstract: Disclosed are novel 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid amides, and their pharmaceutically acceptable salts and esters, that are selective inhibitors of KDR and/or FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular solid cancerous tumors of the breast, colon, lung and prostate. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer using these compounds.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 24, 2011
    Inventors: Kin-Chun Luk, Lee Apostle McDermott, Pamela Loreen Rossman, Peter Michael Wovkulich, Zhuming Zhang
  • Patent number: 7728029
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: June 1, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Kevin William Anderson, Nader Fotouhi, Paul Gillespie, Robert Alan Goodnow, Jr., Kevin Richard Guertin, Nancy-Ellen Haynes, Michael Paul Myers, Sherrie Lynn Pietranico-Cole, Lida Qi, Pamela Loreen Rossman, Nathan Robert Scott, Kshitij Chhabilbhai Thakkar, Jefferson Wright Tilley, Qiang Zhang
  • Publication number: 20080009515
    Abstract: There are provided compounds of the formula wherein R1, R2, R3, X, ring A and ring B are as described. The compounds exhibit anticancer properties.
    Type: Application
    Filed: June 18, 2007
    Publication date: January 10, 2008
    Inventors: Yi Chen, Kin-Chun Luk, Pamela Loreen Rossman, Sung-Sau So
  • Publication number: 20070225280
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
    Type: Application
    Filed: March 14, 2007
    Publication date: September 27, 2007
    Inventors: Kevin William Anderson, Nader Fotouhi, Paul Gillespie, Robert Alan Goodnow, Kevin Richard Guertin, Nancy-Ellen Haynes, Michael Paul Myers, Sherrie Lynn Pietranico-Cole, Lida Qi, Pamela Loreen Rossman, Nathan Robert Scott, Kshitij Chhabilbhai Thakkar, Jefferson Wright Tilley, Qiang Zhang
  • Patent number: 7129351
    Abstract: Disclosed are novel pyrimido compounds that are inhibitors of Src family of tyrosine kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, hepatic and pancreatic tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: October 31, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Kin-Chun Luk, Pamela Loreen Rossman, Stefan Scheiblich, Sung-Sau So
  • Patent number: 7115740
    Abstract: Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: October 3, 2006
    Assignee: Hoffmann-la Roche Inc.
    Inventors: Yi Chen, Apostolos Dermatakis, Jin-Jun Liu, Kin-Chun Luk, Christophe Michoud, Pamela Loreen Rossman
  • Patent number: 7112676
    Abstract: Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases and are selective against LCK. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: September 26, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Apostolos Dermatakis, Marek Michal Kabat, Kin-Chun Luk, Pamela Loreen Rossman, Sung-Sau So
  • Publication number: 20040204427
    Abstract: Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
    Type: Application
    Filed: April 2, 2004
    Publication date: October 14, 2004
    Inventors: Yi Chen, Apostolos Dermatakis, Jin-Jun Liu, Kin-Chun Luk, Christophe Michoud, Pamela Loreen Rossman
  • Publication number: 20040110773
    Abstract: Disclosed are novel pyrimido compounds that are inhibitors of Src family of tyrosine kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, hepatic and pancreatic tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
    Type: Application
    Filed: October 20, 2003
    Publication date: June 10, 2004
    Inventors: Kin-Chun Luk, Pamela Loreen Rossman, Stefan Scheiblich, Sung-Sau So