Patents by Inventor Pamela M. Carroll

Pamela M. Carroll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT METHODS
    Publication number: 20230057310
    Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 23, 2023
    Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
  • TREATMENT METHODS
    Publication number: 20230041057
    Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for treating subjects having cancer, are provided herein.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 9, 2023
    Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
  • TREATMENT METHODS
    Publication number: 20210199644
    Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.
    Type: Application
    Filed: October 30, 2020
    Publication date: July 1, 2021
    Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
  • Treatment methods
    Patent number: 10859566
    Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: December 8, 2020
    Assignee: GENOCEA BIOSCIENCES, INC.
    Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
  • TREATMENT METHODS
    Publication number: 20190072543
    Abstract: Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein.
    Type: Application
    Filed: March 20, 2018
    Publication date: March 7, 2019
    Inventors: Jessica Baker Flechtner, Marie Lossky-Elias, Pamela M. Carroll, Hubert Lam, Lisa K. McNeil, Wendy Jane Broom
  • tumor necrosis factor class molecule (“DmTNFv2”)
    Patent number: 7288632
    Abstract: The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and homologs thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, in addition to methods of genetically modifying Drosophila or cultured cells to express or mis-express DmTNF, DmTNFv1, or DmTNFv2. The invention also relates to the use of such modified insects or cells to characterize DmTNF activity, identify TNF-like genes and/or genes implicated in modulating TNF, characterize TNF signaling pathways, and/or to identify modulators of DmTNF activity.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: October 30, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Pamela M. Carroll, Jian Chen, Chandra S. Ramanathan, Hong Xiao, Bo Guan, Michael A. Bowen
  • Drosophila tumor necrosis factor class molecule polynucleotides and variants thereof
    Patent number: 7037676
    Abstract: The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and homologs thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, in addition to methods of genetically modifying Drosophila or cultured cells to express or mis-express DmTNF, DmTNFv1, or DmTNFv2. The invention also relates to the use of such modified insects or cells to characterize DmTNF activity, identify TNF-like genes and/or genes implicated in modulating TNF, characterize TNF signaling pathways, and/or to identify modulators of DmTNF activity.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: May 2, 2006
    Assignee: Bristol-Myers Squibb
    Inventors: Pamela M. Carroll, Jian Chen, Chandra S. Ramanathan, Hong Xiao, Michael A. Bowen
  • Novel drosophila tumor necrosis factor class molecule ("DmTNF") and variants thereof
    Publication number: 20020012968
    Abstract: The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides encoding two Drosophila DmTNF variants, DmTNFv1 and DmTNFv2 polypeptides, fragments and homologs thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, in addition to methods of genetically modifying Drosophila or cultured cells to express or mis-express DmTNF, DmTNFv1, or DmTNFv2. The invention also relates to the use of such modified insects or cells to characterize DmTNF activity, identify TNF-like genes and/or genes implicated in modulating TNF, characterize TNF signaling pathways, and/or to identify modulators of DmTNF activity.
    Type: Application
    Filed: March 20, 2001
    Publication date: January 31, 2002
    Inventors: Pamela M. Carroll, Jian Chen, Chandra S. Ramanathan, Hong Xiao, Bo Guan, Michael A. Bowen