Patents by Inventor PAMELA MARY PEGMAN

PAMELA MARY PEGMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELLS AND METHOD OF CELL CULTURE
    Publication number: 20240093248
    Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.
    Type: Application
    Filed: July 12, 2023
    Publication date: March 21, 2024
    Applicant: Pfizer Inc.
    Inventors: Gregory Walter HILLER, Jeffrey Joseph MITCHELL, Bhanu Chandra MULUKUTLA, Pamela Mary PEGMAN
  • Cells and method of cell culture
    Patent number: 11718864
    Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: August 8, 2023
    Assignee: Pfizer Inc.
    Inventors: Gregory Walter Hiller, Jeffrey Joseph Mitchell, Bhanu Chandra Mulukutla, Pamela Mary Pegman
  • CELLS AND METHOD OF CELL CULTURE
    Publication number: 20210017553
    Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 21, 2021
    Applicant: PFIZER INC.
    Inventors: Gregory Walter HILLER, Jeffrey Joseph MITCHELL, Bhanu Chandra MULUKUTLA, Pamela Mary PEGMAN
  • Cells having reduced BCAT1
    Patent number: 10738334
    Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: August 11, 2020
    Assignee: Pfizer Inc.
    Inventors: Gregory Walter Hiller, Jeffrey Joseph Mitchell, Bhanu Chandra Mulukutla, Pamela Mary Pegman
  • TYROSINE PROTOTROPHY
    Publication number: 20200056190
    Abstract: Provided herein is a tyrosine selection marker system, and uses thereof. In some embodiments, nucleic acid constructs, vectors, host cells and related compositions and methods for generating and selecting tyrosine prototroph cells are provided.
    Type: Application
    Filed: March 9, 2018
    Publication date: February 20, 2020
    Applicant: PFIZER INC.
    Inventors: Gregory Walter HILLER, Jeffrey Joseph MITCHELL, Bhanu Chandra MULUKUTLA, Pamela Mary PEGMAN
  • CELLS AND METHOD OF CELL CULTURE
    Publication number: 20180265904
    Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.
    Type: Application
    Filed: September 22, 2016
    Publication date: September 20, 2018
    Applicant: PFIZER INC.
    Inventors: GREGORY WALTER HILLER, JEFFREY JOSEPH MITCHELL, BHANU CHANDRA MULUKUTLA, PAMELA MARY PEGMAN