Patents by Inventor Pamela P. Peralta-Yahya

Pamela P. Peralta-Yahya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins useful for producing pinene
    Patent number: 9376691
    Abstract: The present invention provides for a modified host cell comprising a heterologous pinene synthase (PS), or enzymatically active fragment or variant thereof, and optionally a geranyl pyrophosphate synthase (GPPS), or enzymatically active fragment or variant thereof, or a fusion protein comprising: (a) a PS and (b) a GPPS linked by a linker.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: June 28, 2016
    Assignee: The Regents of the University of California
    Inventors: Pamela P. Peralta-Yahya, Jay D. Keasling
  • RAPID DISCOVERY AND SCREENING OF ENZYME ACTIVITY USING MASS SPECTROMETRY
    Publication number: 20150330992
    Abstract: Described herein are methods, systems, and compositions for detecting enzyme activity. In some embodiments, the reaction product(s) are coupled with a mass tag, and the enzyme activity is determiner by analyzing the reaction product(s). The enzyme assays can be performed using mass spectrometry, for example nanostructure-initiator mass spectrometry (NIMS). Also described are methods, systems, and compositions for monitoring enzymatic degradation process of a substrate sample, for example a biomass.
    Type: Application
    Filed: December 11, 2013
    Publication date: November 19, 2015
    Applicants: The Regents of the University of California, Sandia Corporation
    Inventors: Trent R Northen, Kai Deng, Tristan P De Rond, Pamela P Peralta-Yahya, Xiaoliang Cheng, Jay D Keasling
  • Host Cells and Constructs Useful for Producing Pinene
    Publication number: 20140295517
    Abstract: The present invention provides for a modified host cell comprising a heterologous pinene synthase (PS), or enzymatically active fragment or variant thereof, and optionally a geranyl pyrophosphate synthase (GPPS), or enzymatically active fragment or variant thereof, or a fusion protein comprising: (a) a PS and (b) a GPPS linked by a linker.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 2, 2014
    Applicant: The Regents of the University of California
    Inventors: Pamela P. Peralta-Yahya, Jay D. Keasling
  • Cell-Mediated Directed Evolution
    Publication number: 20090209038
    Abstract: The present invention relates to systems which harness the molecular biology of a living cell to direct evolution of biological entities of interest. According to the invention, a host cell is engineered to facilitate mutation of a nucleic acid target corresponding to that entity and select for desirable mutants. As applied to populations of host cells, the invention provides a means to generate and contemporaneously select mutants of interest, allowing for the production of extremely diverse libraries enriched in the most ‘fit’ mutants.
    Type: Application
    Filed: January 5, 2009
    Publication date: August 20, 2009
    Inventors: Virginia W. Cornish, Pamela P. Peralta-Yahya, Jonathan Eiseman Bronson