Patents by Inventor Pamela R. Contag
Pamela R. Contag has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8986962Abstract: This invention provides co-cultures of photosynthetic microorganisms and biofuel producing microorganisms. In certain embodiments, polysaccharide-producing, photosynthetic microorganisms are microalgae having frustules provide a substrate on which biofuel-producing microorganisms can grow. In other embodiments, the photosynthetic microorganisms produce a lipid and the non-photosynthetic microorganisms produce a solvent in which the lipid is soluble.Type: GrantFiled: July 21, 2011Date of Patent: March 24, 2015Inventor: Pamela R. Contag
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Patent number: 8545814Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: June 13, 2007Date of Patent: October 1, 2013Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 8349602Abstract: The present invention relates to biodetectors for detecting and quantifying molecules in liquid, gas, or matrices. More specifically, the present invention relates to biodetectors comprising a molecular switching mechanism to express a reporter gene upon interaction with target substances. The invention further relates to methods using such biodetectors for detecting and quantifying selected substances with high specificity and high sensitivity.Type: GrantFiled: April 18, 1997Date of Patent: January 8, 2013Assignee: Xenogen CorporationInventors: Pamela R. Contag, David A. Benaron, Christopher H. Contag
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Publication number: 20120124898Abstract: This invention provides co-cultures of photosynthetic microorganisms and biofuel producing microorganisms. In certain embodiments, polysaccharide-producing, photosynthetic microorganisms are microalgae having frustules provide a substrate on which biofuel-producing microorganisms can grow. In other embodiments, the photosynthetic microorganisms produce a lipid and the non-photosynthetic microorganisms produce a solvent in which the lipid is soluble.Type: ApplicationFiled: July 21, 2011Publication date: May 24, 2012Inventor: Pamela R. Contag
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Publication number: 20090041668Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: ApplicationFiled: June 13, 2007Publication date: February 12, 2009Inventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 7449615Abstract: The present invention relates to panels of reporter expression cassettes and the generation of transgenic non-human animals, wherein said reporter expression cassettes have selected control elements operable linked to reporter genes. The invention includes methods of use thereof for the identification and characterization of the effects of compounds administered to the live transgenic non-human animals.Type: GrantFiled: December 16, 1999Date of Patent: November 11, 2008Assignee: Xenogen CorporationInventors: Pamela R. Contag, Ning Zhang
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Publication number: 20080226563Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: ApplicationFiled: June 13, 2007Publication date: September 18, 2008Inventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 7255851Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: June 2, 2005Date of Patent: August 14, 2007Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 7198774Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: June 8, 2005Date of Patent: April 3, 2007Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6964856Abstract: Methods for selecting a candidate drug for treating sepsis are disclosed. The methods involve labeling a sepsis-causing pathogen with a reporter and monitoring the progress of infection by detecting levels of the reporter in animals treated with test compounds or drugs. The comparisons may be made between experimental and control animals, as well as within a single animal or group of animals. Also disclosed is a method for predicting an expected time of death of an experimental animal in a model system of sepsis using data generated in the initial part of the experiment.Type: GrantFiled: May 15, 2003Date of Patent: November 15, 2005Assignee: Xenogen CorporationInventors: Carole Bellinger-Kawahara, Pamela R. Contag, Alan Hubbard
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Patent number: 6939533Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: July 24, 2002Date of Patent: September 6, 2005Assignee: Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6923951Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: December 16, 2002Date of Patent: August 2, 2005Assignee: Board of Trustees of the Leland Stanford UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6916462Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: December 16, 2002Date of Patent: July 12, 2005Assignee: Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6908605Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: December 16, 2002Date of Patent: June 21, 2005Assignee: Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6890515Abstract: Methods an compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease state are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: December 16, 2002Date of Patent: May 10, 2005Assignee: Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Publication number: 20040235003Abstract: The present invention relates to biodetectors for detecting and quantifying molecules in liquid, gas, or matrices. More specifically, the present invention relates to biodetectors comprising a molecular switching mechanism to express a reporter gene upon interaction with target substances. The invention further relates to methods using such biodetectors for detecting and quantifying selected substances with high specificity and high sensitivity.Type: ApplicationFiled: September 18, 2003Publication date: November 25, 2004Applicant: Xenogen CorporationInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Patent number: 6737245Abstract: The present invention relates to bacterial luciferase expression cassettes suitable for conferring bioluminescence properties on Gram-positive bacteria, cells transformed with such cassettes, and methods of making and using such cassettes.Type: GrantFiled: September 7, 2000Date of Patent: May 18, 2004Assignee: Xenogen CorporationInventors: Kevin P. Francis, Pamela R. Contag, Danny J. Joh
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Patent number: 6649143Abstract: Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.Type: GrantFiled: January 19, 1999Date of Patent: November 18, 2003Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron
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Publication number: 20030203418Abstract: Methods for selecting a candidate drug for treating sepsis are disclosed. The methods involve labeling a sepsis-causing pathogen with a reporter and monitoring the progress of infection by detecting levels of the reporter in animals treated with test compounds or drugs. The comparisons may be made between experimental and control animals, as well as within a single animal or group of animals. Also disclosed is a method for predicting an expected time of death of an experimental animal in a model system of sepsis using data generated in the initial part of the experiment.Type: ApplicationFiled: May 15, 2003Publication date: October 30, 2003Inventors: Carole Bellinger-Kawahara, Pamela R. Contag, Alan Hubbard
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Patent number: 6638752Abstract: The present invention relates to biodetectors for detecting and quantifying molecules in liquid, gas, or matrices. More specifically, the present invention relates to biodetectors comprising a molecular switching mechanism to express a reporter gene upon interaction with target substances. The invention further relates to methods using such biodetectors for detecting and quantifying selected substances with high specificity and high sensitivity.Type: GrantFiled: October 30, 1998Date of Patent: October 28, 2003Assignee: Xenogen CorporationInventors: Pamela R. Contag, Christopher H. Contag, David A. Benaron