Patents by Inventor Pamela R. Stergios

Pamela R. Stergios has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous solubility pharmaceutical formulations
    Patent number: 6511681
    Abstract: A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a normally hydrophobic vehicle is described. The amorphous state is stabilized by the composition of the formulation, providing long shelf life of the improved composition. This stabilized formulation also provides increased solubility and bioavailability of the active agent. Solutions of the active agent are stabilized by the composition, preventing recrystallization and precipitation of the less soluble, crystalline form of the active agent from aqueous solutions thereof.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: January 28, 2003
    Assignee: R.P. Scherer Technologies, Inc.
    Inventors: Ronald S. Vladyka, Jr., David F. Erkoboni, Pamela R. Stergios
  • Aqueous solubility pharmaceutical formulations
    Patent number: 6497905
    Abstract: A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a normally hydrophobic vehicle is described. The amorphous state is stabilized by the composition of the formulation, providing long shelf life of the improved composition. This stabilized formulation also provides increased solubility and bioavailability of the active agent. Solutions of the active agent are stabilized by the composition, preventing recrystallization and precipitation of the less soluble, crystalline form of the active agent from aqueous solutions thereof.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: December 24, 2002
    Assignee: R.P. Scherer Technologies, Inc.
    Inventors: Ronald S. Vladyka, Jr., David F. Erkoboni, Pamela R. Stergios
  • Method of making granular pharmaceutical vehicle
    Patent number: 6379707
    Abstract: A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a normally hydrophobic vehicle is described. The amorphous state is stabilized by the composition of the formulation, providing long shelf life of the improved composition. This stabilized formulation also provides increased solubility and bioavailability of the active agent. Solutions of the active agent are stabilized by the composition, preventing recrystallization and precipitation of the less soluble, crystalline form of the active agent from aqueous solutions thereof.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: April 30, 2002
    Assignee: FMC Corporation
    Inventors: Ronald S. Vladyka, Jr., David F. Erkoboni, Pamela R. Stergios
  • Aqueous solubility pharmaceutical formulations
    Publication number: 20020037324
    Abstract: A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a normally hydrophobic vehicle is described. The amorphous state is stabilized by the composition of the formulation, providing long shelf life of the improved composition. This stabilized formulation also provides increased solubility and bioavailability of the active agent. Solutions of the active agent are stabilized by the composition, preventing recrystallization and precipitation of the less soluble, crystalline form of the active agent from aqueous solutions thereof.
    Type: Application
    Filed: June 21, 2001
    Publication date: March 28, 2002
    Applicant: FMC Corporation
    Inventors: Ronald S. Vladyka, David F. Erkoboni, Pamela R. Stergios
  • METHOD OF MAKING GRANULAR PHARMACEUTICAL VEHICLE
    Publication number: 20020012706
    Abstract: A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a normally hydrophobic vehicle is described. The amorphous state is stabilized by the composition of the formulation, providing long shelf life of the improved composition. This stabilized formulation also provides increased solubility and bioavailability of the active agent. Solutions of the active agent are stabilized by the composition, preventing recrystallization and precipitation of the less soluble, crystalline form of the active agent from aqueous solutions thereof.
    Type: Application
    Filed: June 21, 2001
    Publication date: January 31, 2002
    Applicant: FMC Corporation
    Inventors: Ronald S. Vladyka, David F. Erkoboni, Pamela R. Stergios