Abstract: A multi-layered polyurethane foam dressing with cooling properties for use in body cavities, on damaged tissues, particularly burns, or for cosmetic use. The dressing includes: 1) an optional outer layer of either a hydrogel formulated from a polyurethane or an adhesive elastomeric material; 2) a hydrophilic polyurethane foam layer; 3) a non-adherent surface-contacting cooling layer of a polyurethane hydrogel; and, 4) an optional protective cover-sheet. An interposed liquid transfer control may be used at a layer interface. The dressing can be in various shapes and sizes (e.g., cylindrical, oval, etc. or flat sheets). A secondary wrapping dressing may be applied to secure the dressing. The contact surface may be channeled to enhance fluid distribution.

Abstract: The invention disclosed is a composition and method for the slow sustained ocular delivery of a prophylactic agent contained in liposome vesicles. The liposome vesicles are composed of phospholipid and cholesterol in a molar ratio of phospholipid to cholesterol of 8:2 to 1:1. Preferably, stearylamine is included in the liposome composition.