Patents by Inventor Pankaj Jay Pasricha

Pankaj Jay Pasricha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190201692
    Abstract: A method for treating conditions associated with impaired glucose control, involving inhibition of signalling by the greater splanchnic nerve leads to a significant improvement in oral glucose tolerance.
    Type: Application
    Filed: May 19, 2017
    Publication date: July 4, 2019
    Inventors: Arun SRIDHAR, Liansheng LIU, Pankaj Jay PASRICHA
  • Patent number: 9717616
    Abstract: Methods and devices for treating obesity. Pressure is applied to gastric walls in at least one segment of a stomach such that the pressure distends the gastric walls and induces satiety. A hollow capsule can be used to distend the gastric walls. Alternatively, a doughnut-shaped ring may be inflated to an amount sufficient to create intragastric tension and induce satiety. A c-ring including at least one balloon may be placed at a segment of the stomach, where the balloon inflates to a size that creates tension at the segment. A biocompatible material can be injected into the fundus and antrum of the stomach to stiffen the gastric wall to create a fullness feeling.
    Type: Grant
    Filed: August 1, 2011
    Date of Patent: August 1, 2017
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Pankaj Jay Pasricha
  • Patent number: 9555020
    Abstract: Methods of treatment in subjects suffering from diabetes mellitus or obesity are provided. The methods comprise the step of administering an active agent directly to the small intestine in the subject. In particular, the active agent may be administered directly to the duodenum in the subject. The active agents useful in the treatments described herein include analgesic agents and, in particular, antinociceptive agents such as capsaicin, resiniferatoxin, and their analogs.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: January 31, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Pankaj Jay Pasricha, Liansheng Liu
  • Patent number: 9023066
    Abstract: A treatment device for endoscopic therapy of the present invention includes a suturing-ligating member having a distal end portion and a proximal end portion, that carries out at least one of suturing and ligation of biological tissue, a stopper provided to be movable forward or backward on an proximal end side of the suturing or ligating member, and stoppable by friction on the suturing-ligating member to maintain the biological tissue in a sutured or ligated state by the suturing-ligating member, and a suturing-ligation releasing member provided movable with relative to the suturing-ligating member to release the suturing-ligation state maintained by firctional stopping between the suturing-ligating member and the stopper by moving the releasing member to the proximal end portion side of the suturing-ligating member.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: May 5, 2015
    Assignees: Olympus Corporation, Apollo Endosurgery, Inc.
    Inventors: Pankaj Jay Pasricha, Yuji Sakamoto, Satoshi Miyamoto, Yoshio Onuki, Norio Onishi
  • Publication number: 20140371834
    Abstract: The present invention is directed to a method of regulating gastrointestinal action in a subject using a stimulatory electrode and a sensor to provide retrograde feedback control of electrical stimulation to the GI tract.
    Type: Application
    Filed: May 24, 2014
    Publication date: December 18, 2014
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Jiande Chen, Pankaj Jay Pasricha
  • Publication number: 20140187619
    Abstract: Methods of treatment in subjects suffering from diabetes mellitus or obesity are provided. The methods comprise the step of administering an active agent directly to the small intestine in the subject. In particular, the active agent may be administered directly to the duodenum in the subject. The active agents useful in the treatments described herein include analgesic agents and, in particular, antinociceptive agents such as capsaicin, resiniferatoxin, and their analogues.
    Type: Application
    Filed: July 18, 2012
    Publication date: July 3, 2014
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Pankaj Jay Pasricha, Liansheng Liu
  • Patent number: 8761903
    Abstract: The present invention is directed to a method of regulating gastrointestinal action in a subject using a stimulatory electrode and a sensor to provide retrograde feedback control of electrical stimulation to the GI tract.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: June 24, 2014
    Assignee: The Board of Regents of the University of Texas
    Inventors: Jiande Chen, Pankaj Jay Pasricha
  • Publication number: 20140134167
    Abstract: Provided herein are methods for treating pain and for reducing the excitability of nociceptors, comprising administering a TGF-? antagonist. In some embodiments, a TGF-? antagonist is a monoclonal TGF-f3 neutralizing antibody or a fusion product comprising a monoclonal TGF-? neutralizing antibody, a soluble receptor, an antisense oligodeoxynucleotides (ODNs), a ribozymes, a small inhibitory RNA (siRNA), Smad 6, Smad7, or a small molecule that blocks TGF-? signaling.
    Type: Application
    Filed: December 26, 2011
    Publication date: May 15, 2014
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Pankaj Jay Pasricha
  • Patent number: 8594811
    Abstract: The present invention is directed to a method of regulating gastrointestinal action in a subject using a stimulatory electrode and a sensor to provide retrograde feedback control of electrical stimulation to the GI tract. The invention is further directed to a method for reducing weight in a subject, again using a stimulatory electrode and a sensor to provide retrograde feedback control of electrical stimulation to the stomach. The invention is further directed to a method of providing electrical field stimulation to a gastrointestinal organ, as well as a method of providing an electrical potential gradient in a gastrointestinal organ. Further provided is a method of stimulating the vagus nerve of a subject. Additionally provided is a method of placing a device in the gastrointestinal tract or wall of a subject from the exterior of the subject, using a needle to insert the device.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: November 26, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Jiande Chen, Pankaj Jay Pasricha
  • Patent number: 8560053
    Abstract: A method is disclosed for distending a body lumen in the performance of endoscopic retrograde cholangiopancreatography (ERCP). The method comprises insufflating the body lumen with contrast agent to distend the body lumen. The contrast agent includes gas.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: October 15, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Pankaj Jay Pasricha
  • Patent number: 8467884
    Abstract: The present invention is directed to a method of stimulating the vagus nerve of a subject.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: June 18, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Jiande Chen, Pankaj Jay Pasricha
  • Patent number: 8467874
    Abstract: The disclosure provides a method of treatment for obesity, in an individual in need thereof, by administering electrical stimulation at dual sites in the gastrointestinal tract. The electrical stimulations are administered by positioning bipolar stimulatory electrodes in contact with the gastric and dudenol cavities, along afferent vagal neural pathways, in the gastrointestinal tract. The electrical stimulations thus administered, activate the vagal afferents associated with the gastric and dudenol sites in the gastrointestinal tract. The activation of vagal afferents modulates the gastrointestinal peptide satiety hormones. Further, the disclosure provides a method of treatment for eating disorders, in an individual in need thereof, by administering electrical stimulation at dual sites, along afferent vagal neural pathways, in the gastrointestinal tract.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: June 18, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Jiande Chen, Pankaj Jay Pasricha
  • Patent number: 8465499
    Abstract: A medical apparatus including: a projecting member; an introducing sheath; an extrusion member inside the introducing sheath, at a proximal side of the projecting member and movable in an axial direction with respect to the introducing sheath; a cover sheath outside the introducing sheath, the introducing sheath being movable between a first and second position with respect to the cover sheath; an introducing sheath manipulating section at a proximal side of the introducing sheath; an extrusion member manipulating section at a proximal side of the extrusion member; a cover sheath manipulating section at a proximal side of the cover sheath; and a release member on the cover sheath manipulating section and/or the introducing sheath manipulating section to release a fixation between the extrusion member manipulating section and the introducing sheath manipulating section when the introducing sheath is disposed on the first or second position.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: June 18, 2013
    Assignees: Olympus Corporation, Apollo Endosurgery, Inc.
    Inventors: Yoshio Onuki, Satoshi Miyamoto, Koichi Kawashima, Pankaj Jay Pasricha
  • Publication number: 20130090526
    Abstract: There is provided an endoscopic system. The system comprises a flexible endoscope insertable into a first tubular organ from a natural opening of a human body. The system further comprises an opening member which forms on a wall part of the first tubular organ an opening used to insert the endoscope into an abdominal cavity from the first tubular organ in the body, an anastomosing member which is able to anastomoses the first tubular organ with a second tubular organ in the abdominal cavity, and a cutting member with which the second tubular organ is able to be cut.
    Type: Application
    Filed: November 30, 2012
    Publication date: April 11, 2013
    Inventors: Keita SUZUKI, Tetsuya YAMAMOTO, Yoshio ONUKI, Satoshi MIYAMOTO, Masahiro ISHIKAWA, Anthony Nicholas KALLOO, Sergey Veniaminovich KANTSEVOY, Pankaj Jay PASRICHA, Sydney Sheung Chee CHUNG
  • Patent number: 8417331
    Abstract: The present invention relates to a method of providing electrical stimulation to a liver of a subject which includes providing one or more stimulatory electrodes to the liver of the subject and providing electrical stimulation to the liver of the subject. The invention further relates to methods of reducing risk factors of metabolic syndrome, treating diabetes, treating a subject having eating disorders and reducing glucose levels of a subject using methods of the present invention.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: April 9, 2013
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Pankaj Jay Pasricha, Jiande Chen
  • Patent number: 8337395
    Abstract: There is provided an endoscopic system. The system comprises a flexible endoscope insertable into a first tubular organ from a natural opening of a human body. The system further comprises an opening member which forms on a wall part of the first tubular organ an opening used to insert the endoscope into an abdominal cavity from the first tubular organ in the body, an anastomosing member which is able to anastomoses the first tubular organ with a second tubular organ in the abdominal cavity, and a cutting member with which the second tubular organ is able to be cut.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: December 25, 2012
    Assignees: Olympus Corporation, Apollo Endosurgery, Inc.
    Inventors: Keita Suzuki, Tetsuya Yamamoto, Yoshio Onuki, Satoshi Miyamoto, Masahiro Ishikawa, Anthony Nicholas Kalloo, Sergey Veniaminovich Kantsevoy, Pankaj Jay Pasricha, Sydney Sheung Chee Chung
  • Publication number: 20120164139
    Abstract: Provided herein are methods of treating gastrointestinal motility disorders by targeting the dopamine 3 receptor (D3R). A D3R agonist is administered to a subject to decrease gastrointestinal motility to treat the disorder. A D3R antagonist is administered to a subject to decrease gastrointestinal motility to treat the disorder.
    Type: Application
    Filed: March 6, 2012
    Publication date: June 28, 2012
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Pankaj Jay Pasricha, Maria-Adelaide Micci
  • Patent number: 8142448
    Abstract: A tissue puncturing system used to suture tissues in a body cavity including: an endoscope; a flexible sheath having a distal portion provided with at least a side opening and a lumen, through which an endoscope may pass; at least one mechanism for puncturing tissue disposed in the flexible sheath, and having a pointed end, which is movable from a first position to a second position; and an operation mechanism for moving the mechanism for puncturing between the first and second positions.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: March 27, 2012
    Assignees: Olympus Corporation, Apollo Endosurgery, Inc.
    Inventors: Pankaj Jay Pasricha, Keiichi Arai, Koichi Kawashima, Keita Suzuki, Koh Kimura, Tsukasa Kobayashi, Yoshihiko Sugi, Tetsuya Yamamoto, Yoshio Onuki
  • Publication number: 20120071867
    Abstract: Embodiments of the present invention provide improved laser systems and methods for endoscopic laser treatment of abnormal tissue such as abnormal mucosal tissue, for example esophageal dysplasia that is also referred to as Barrett's esophagus (BE). The systems and methods described here can also be used in many applications where treatment of shallow surface layers with minimal damage to the tissue beneath is desirable, for example BE tissue comprising hemoglobin. In many embodiments, the system is configured to emit light energy having an optical wavelength to treat tissue having oxygenated hemoglobin.
    Type: Application
    Filed: March 18, 2011
    Publication date: March 22, 2012
    Applicant: Metalase, Inc.
    Inventors: Andrew Ryan, Ramsey Shanbaky, Pankaj Jay Pasricha
  • Patent number: 8105342
    Abstract: In the case where the living tissues in the patient's body is resected as well, it is possible to suture the resected portion immediately without replacement with another treatment device after resection. Thus, prevention of bleeding from the resected portion or earlier repair of an ulcer that occurs with the resected portion can be carried out for the patent lowly invasively and easily.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: January 31, 2012
    Assignee: Apollo Endosurgery, Inc.
    Inventors: Yoshio Onuki, Satoshi Miyamoto, Koichi Kawashima, Pankaj Jay Pasricha