Abstract: A transdermal drug delivery patch with an array of spatially organized reservoirs. The invention provides greater penetration of drug into the skin compared to current transdermal drug delivery systems, and facilitates the delivery of drugs that are presently refractory to transdermal delivery due to high molecular weight.

Abstract: This invention describes a novel method for rapid screening of formulations for drug delivery, which uses a high throughput array to screen multiple samples. This method monitors the depletion of a test substance from a donor well, the migration of the substance into a test membrane, and/or the migration of the substance through a membrane into a receptor well. It can be used to discover new formulations as well as to optimize the existing formulations for delivering drugs via transdermal, oral, or injectable routes.