Patents by Inventor Pano Theodoropoulos

Pano Theodoropoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
    Patent number: 10082496
    Abstract: The described invention provides methods for targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: September 25, 2018
    Assignee: Board of Regents of the University of Texas System
    Inventors: Jef De Brabander, Jerry W. Shay, Wentian Wang, Deepak Nijhawan, Pano Theodoropoulos
  • Methods and compositions for selective and targeted cancer therapy
    Patent number: 9789096
    Abstract: Provided herein are methods and compositions for selective and targeted cancer therapy, in particular certain benzothiophenes, benzothiazoles, oxalamides, N-acyl ureas and chromones, and their use in selectively treating certain adenocarcinomas. In some embodiments, the selective toxicity of the compounds may be mediated through SCD1 and/or CYP450 such as CYP4F11.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: October 17, 2017
    Assignee: Board of Regents of the University of Texas System
    Inventors: Joseph M. Ready, Deepak Nijhawan, Stephen S. Gonzales, Pano Theodoropoulos
  • TARGETING EMOPAMIL BINDING PROTEIN (EBP) WITH SMALL MOLECULES THAT INDUCE AN ABNORMAL FEEDBACK RESPONSE BY LOWERING ENDOGENOUS CHOLESTEROL BIOSYNTHESIS
    Publication number: 20160313302
    Abstract: The described invention provides methods for targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis.
    Type: Application
    Filed: July 5, 2016
    Publication date: October 27, 2016
    Inventors: Jef DeBrabander, Jerry W. Shay, Wentian Wang, Deepak Nijhawan, Pano Theodoropoulos
  • Methods and Compositions for Selective and Targeted Cancer Therapy
    Publication number: 20160200695
    Abstract: Provided herein are methods and compositions for selective and targeted cancer therapy, in particular certain benzothiophenes, benzothiazoles, oxalamides, N-acyl ureas and chromones, and their use in selectively treating certain adenocarcinomas. In some embodiments, the selective toxicity of the compounds may be mediated through SCD1 and/or CYP450 such as CYP4F11.
    Type: Application
    Filed: September 4, 2014
    Publication date: July 14, 2016
    Applicant: Board of Regents of the University of Texas System
    Inventors: Joseph M. Ready, Deepak Nijhawan, Stephen S. Gonzales, Pano Theodoropoulos