Abstract: A chlorine dioxide sustained-releasing sterilizing and disinfecting nano material, and a preparation method and use thereof are disclosed. A support, i.e., a porous material with silicon dioxide as a main component, is soaked in a chlorine dioxide-containing solution to adsorb chlorine dioxide on the surface of silicon dioxide, and the resulting mixture is filtered, and the obtained solid is dried to obtain the chlorine dioxide sustained-releasing sterilizing and disinfecting nano material. When the chlorine dioxide sustained-releasing sterilizing and disinfecting nano material is used for sterilizing and disinfecting, the adsorbed chlorine dioxide reacts with water physically and chemically adsorbed on the surface of the support to generate a large quantity of active groups .OH, and meanwhile sustainedly release dioxide chlorine gas, having a synergistic effect, and thereby enabling the material finally to exhibit high-efficiency and excellent sterilizing and disinfecting performance.