Abstract: Tile stream selection for mobile bandwidth optimization is disclosed. Also disclosed is a method that includes storing a plurality of video tiles combinable to form a larger portion or all of a high resolution video. The method also includes processing a request to stream at least a first video tile of the video tiles. The processing includes determining a size of a first portion of a region of interest falling within the first video tile; determining whether the size of the first portion is below a threshold size; and transmitting, over at least one network, a first video stream that includes the first video tile. The first video tile is transmitted in: a first resolution when the size of the first portion is below the threshold size; and a second resolution when the size of the first portion is above the threshold size.