Patents by Inventor Paola Allavena

Paola Allavena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-Inflammatory Agents
    Publication number: 20080242670
    Abstract: We have found anti-inflammatory activity in the ecteinascidin compounds. Such compounds have been widely described, and may have the following general formula (I), wherein: R5 is OH, alkoxy or alkanoyloxy; R6 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R12 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R16 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R17 is OH, alkoxy or alkanoyloxy; R18 is OH, alkoxy or alkanoyloxy; R21 is H, OH, CN or another nucleophilic group; and Ra is hydrogen and Rb is optionally substituted amino, or Ra with Rb form a carbonyl function ?O, or Ra, Rb and the carbon to which they are attached form a tetrahydroisoquinoline group.
    Type: Application
    Filed: May 14, 2007
    Publication date: October 2, 2008
    Applicant: Pharma Mar S.A., Sociedad Unipersonal
    Inventors: Paola Allavena, Maurizio D'Incalci, Glynn Faircloth
  • Anti-Inflammatory Agents
    Publication number: 20080076772
    Abstract: We have found anti-inflammatory activity in the ecteinascidin compounds. Such compounds have been widely described, and may have the following general formula (I): wherein: R5 is OH, alkoxy or alkanoyloxy; R6 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R12 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R16 is hydrogen, alkyl, alkenyl, alkynyl or aryl; R17 is OH, alkoxy or alkanoyloxy; R18 is OH, alkoxy or alkanoyloxy; R21 is H, OH, CN or another nucleophilic group; and Ra is hydrogen and Rb is optionally substituted amino, or Ra with Rb form a carbonyl function ?O, or Ra, Rb and the carbon to which they are attached form a tetrahydroisoquinoline group.
    Type: Application
    Filed: September 28, 2005
    Publication date: March 27, 2008
    Applicant: Pharma Mar S.A. Sociedad Unipersonal
    Inventors: Paola Allavena, Maurizio D'Incalci, Glynn Thomas Faircloth