Patents by Inventor Paola Lembo

Paola Lembo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel G Protein-Coupled Receptor
    Publication number: 20090226932
    Abstract: The present invention is directed to novel G protein-coupled receptors that are found predominantly in the dorsal root ganglia. The invention encompasses both the receptor proteins as well as nucleic acids encoding the proteins. In addition, the present invention is directed to methods and compositions which utilize the receptors.
    Type: Application
    Filed: May 11, 2007
    Publication date: September 10, 2009
    Inventors: Sultan Ahmad, Denis Banville, Yves Fortin, Paola Lembo, Dajan O'Donnell, Shi-Hsiang Shen
  • ASSAYS
    Publication number: 20080064046
    Abstract: The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of bovine adrenal medulla docosapeptide (BAM-22P). The assays are based upon the binding of BAM-22P to the rat and human DRR receptors.
    Type: Application
    Filed: August 14, 2007
    Publication date: March 13, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Sultan Ahmad, Eric Grazzini, Thierry Groblewski, Paola Lembo, Ralf Schmidt
  • Human G protein-coupled receptor expressed in the dorsal root ganglia
    Patent number: 7217693
    Abstract: The present invention is directed to novel G protein-coupled receptors that are found predominantly in the dorsal root ganglia. The invention encompasses both the receptor proteins as well as nucleic acids encoding the proteins. In addition, the present invention is directed to methods and compositions which utilize the receptors.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: May 15, 2007
    Assignee: National Research Council of Canada
    Inventors: Sultan Ahmad, Denis Banville, Yves Fortin, Paola Lembo, Dajan O'Donnell, Shi-Hsiang Shen
  • Method of assaying for agonists or antagonist of Dynorphin A binding to the MAS receptor
    Patent number: 7078177
    Abstract: The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of Dynorphin A and its analogues. The assays are based upon the binding of Dynorphin A and its analogues to the rat and human MAS receptors.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: July 18, 2006
    Assignee: AstraZeneca AB
    Inventors: Sultan Ahmad, Eric Grazzini, Paola Lembo
  • Assays for fprl-1 ligands
    Publication number: 20060141460
    Abstract: Assays for screening for compounds that act as agonists, antagonists, or inverse agonists of CK?8-1 at the FPRL-1 receptor.
    Type: Application
    Filed: September 19, 2003
    Publication date: June 29, 2006
    Inventors: Duncan Henderson, Sylvia Salter, Aram Elagoz, Eric Grazzni, Paola Lembo
  • Novel G protein-coupled receptor
    Publication number: 20060068466
    Abstract: The present invention is directed to novel G protein-coupled receptors that are found predominantly in the dorsal root ganglia. The invention encompasses both the receptor proteins as well as nucleic acids encoding the proteins. In addition, the present invention is directed to methods and compositions which utilize the receptors.
    Type: Application
    Filed: December 30, 2003
    Publication date: March 30, 2006
    Inventors: Sultan Ahmad, Denis Banville, Yves Fortin, Paola Lembo, Dajan O'Donnell, Shi-Hsiang Shen
  • Assays
    Publication number: 20050059575
    Abstract: The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of bovine adrenal medulla docosapeptide (BAM-22P). The assays are based upon the binding of BAM-22P to the rat and human DRR receptors.
    Type: Application
    Filed: October 16, 2001
    Publication date: March 17, 2005
    Inventors: Sultan Ahmad, Eric Grazzini, Thierry Groblewski, Paola Lembo, Ralf Schmidt
  • Method of assaying for agonists or antagonist of dynorphin a binding to the mas receptor
    Publication number: 20040171080
    Abstract: The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of Dynorphin A and its analogues. The assays are based upon the binding of Dynorphin A and its analogues to the rat and human MAS receptors.
    Type: Application
    Filed: June 20, 2003
    Publication date: September 2, 2004
    Inventors: Sultan Ahmad, Eric Grazzini, Paola Lembo
  • G protein-coupled receptors from the rat and human
    Patent number: 6696257
    Abstract: The present invention is directed to novel G protein-coupled receptors that are found predominantly in the dorsal root ganglia. The invention encompasses both the receptor proteins as well as nucleic acids encoding the proteins. In addition, the present invention is directed to methods and compositions which utilize the receptors.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: February 24, 2004
    Assignee: National Research Council of Canada
    Inventors: Sultan Ahmad, Denis Banville, Yves Fortin, Paola Lembo, Dajan O'Donnell, Shi-Hsiang Shen
  • Novel Assays
    Publication number: 20030129664
    Abstract: The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists of sphingosine-1 PO4. The assays are based upon the binding of sphingosine-1 PO4 to the RP-23 receptor.
    Type: Application
    Filed: December 17, 2002
    Publication date: July 10, 2003
    Inventors: Sultan Ahmad, Paola Lembo, Phillippe Walker