Patents by Inventor Paola Nistico

Paola Nistico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METASTASIS SPECIFIC SPLICE VARIANTS OF MENA AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMORS
    Publication number: 20220251662
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Application
    Filed: September 16, 2021
    Publication date: August 11, 2022
    Applicants: Albert Einstein College of Medicine, Massachusetts Institute of Technology, IFO-Regina Elena Cancer Institute
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nistico
  • NEW ONCO-IMMUNOLOGIC PROGNOSTIC AND THERANOSTIC MARKERS
    Publication number: 20200308653
    Abstract: The present invention relates to the identification of a set of prognostic and theranostic markers enabling to assess the tumor microenvironment (immunogenic or immunosuppressive) of solid tumors and predict the responsiveness or the non-responsiveness to immunotherapy of the affected patient.
    Type: Application
    Filed: November 30, 2018
    Publication date: October 1, 2020
    Applicant: ISTITUTI FISIOTERAPICI OSPITALIERI (IFO) - ISTITUTO REGINA ELENA PER LO STUDIO E LA CURA DEI TUMORI
    Inventors: Paola NISTICO', Francesca DI MODUGNO
  • Markers for the epithelial and proliferative or mesenchymal invasive phenotype of human neoplasia
    Patent number: 9939426
    Abstract: The present invention relates to a new Ena/VASP protein isoform, uses thereof, diagnostic methods and kits comprising the same.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 10, 2018
    Assignee: ISTITUTI FISIOTERAPICI OSPITALIERI (IFO)—ISTITUTO REGINA ELENA PER LO STUDIO E LA CURA DEI TUMORI
    Inventors: Paola Nistico′, Francesca Di Modugno
  • METASTASIS SPECIFIC SPLICE VARIANTS OF MENA AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMORS
    Publication number: 20170335406
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 23, 2017
    Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, IFO-REGINA ELENA CANCER INSTITUTE
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nistico
  • Metastasis specific splice variants of Mena and uses thereof in diagnosis, prognosis and treatment of tumors
    Patent number: 9719142
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: August 1, 2017
    Assignees: Albert Einstein College of Medicine, Inc., Massachusetts Institute of Technology, IFO-Regina Elena Cancer Institute
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nistico
  • MARKERS FOR THE EPITHELIAL AND PROLIFERATIVE OR MESENCHYMAL INVASIVE PHENOTYPE OF HUMAN NEOPLASIA
    Publication number: 20160231312
    Abstract: The present invention relates to a new Ena/VASP protein isoform, uses thereof, diagnostic methods and kits comprising the same.
    Type: Application
    Filed: April 22, 2016
    Publication date: August 11, 2016
    Inventors: Paola NISTICO', Francesca Di Modugno
  • METASTASIS SPECIFIC SPLICE VARIANTS OF MENA AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMORS
    Publication number: 20140057966
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Application
    Filed: November 7, 2013
    Publication date: February 27, 2014
    Applicants: Albert Einstein College of Medicine of Yeshiva University, IFO-Regina Elena Cancer Institute, Massachusetts Institute of Technology
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nistico
  • Metastasis specific splice variants of mena and uses thereof in diagnosis, prognosis and treatment of tumors
    Patent number: 8603738
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: December 10, 2013
    Assignees: Albert Einstein College of Medicine of Yeshiva University, Massachusetts Institute of Technology, IFO-Regina Elena Cancer Institute
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nisticò
  • NEW MARKERS FOR THE EPITHELIAL AND PROLIFERATIVE OR MESENCHYMAL INVASIVE PHENOTYPE OF HUMAN NEOPLASIAS
    Publication number: 20130183673
    Abstract: The present invention relates to a new Ena/VASP protein isoform, uses thereof, diagnostic methods and kits comprising the same.
    Type: Application
    Filed: August 11, 2010
    Publication date: July 18, 2013
    Applicant: Istituti Fisioterapici Ospitalieri (IFO) Istituto Regina Elena per lo Studio E la Cura Dei Tumori
    Inventors: Paola Nistico, Francesca Di Modugno
  • HUMAN MENA ISOFORMS SERVE AS MARKERS OF EPITHELIAL TO MESENCHYMAL TRANSITION AND SENSITIVITY TO EGFR INHIBITION IN HUMAN CANCER CELLS
    Publication number: 20120028252
    Abstract: The present invention discloses a method for discriminating between sensitive and resistant tumours to a treatment with EGFR inhibitor drugs comprising: in vitro testing whether tumour material expresses the hMena+11a splicing variant of hMe-na, the tumour positive to said testing being sensitive to the treatment.
    Type: Application
    Filed: July 28, 2008
    Publication date: February 2, 2012
    Inventors: Paola Nistico, Francesca Di Modugno, Maria Simona Pino
  • Metastasis specific splice variants of mena and uses thereof in diagnosis, prognosis and treatment of tumors
    Publication number: 20100047240
    Abstract: Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
    Type: Application
    Filed: July 31, 2009
    Publication date: February 25, 2010
    Inventors: John S. Condeelis, Sumanta Goswami, Frank Gertler, Paola Nisticò