Abstract: According to exemplary embodiments, a secure kiosk for receiving, transmitted, securing, and verifying data may be shown and described. For example, the kiosk may be fully automated. The kiosk may include a display, a tablet computer, a card reader, a printer, and a network link. For example, a kiosk may be provided and may be fully automated. The kiosk may accept data inputs in a variety of manners. The inputted data may then be transmitted, in real time, to a first server, where the information can be displayed and stored. Additionally, the information, at predetermined times, may be transmitted to a number of other servers which may receive, compare, and validate information. Further, a hierarchical data transmission system may be utilized such that, when information is verified or indicated as unverified at any of the other servers, instructions may be sent to at least the first server and the kiosk.

Abstract: The present invention provides methods and compositions for treating cancer patients, and in particular, breast cancer patients, who are responsive to antiprogestin therapy, or who may be induced to be responsive to an antiprogestin therapy through the administration of a demethylation agent, optionally together with an HDAC inhibitor. Further, the present invention relates to a method of screening cancer patients using BCL-XL as a marker protein.

Abstract: According to exemplary embodiments, a secure kiosk for receiving, transmitted, securing, and verifying data may be shown and described. For example, the kiosk may be fully automated. The kiosk may include a display, a tablet computer, a card reader, a printer, and a network link. For example, a kiosk may be provided and may be fully automated. The kiosk may accept data inputs in a variety of manners. The inputted data may then be transmitted, in real time, to a first server, where the information can be displayed and stored. Additionally, the information, at predetermined times, may be transmitted to a number of other servers which may receive, compare, and validate information. Further, a hierarchical data transmission system may be utilized such that, when information is verified or indicated as unverified at any of the other servers, instructions may be sent to at least the first server and the kiosk.

Abstract: The invention provides methods, pharmaceutical compositions and kits for treating a subject having a carcinoma that is resistant to an antiprogestin. In particular, the methods comprise increasing the molar amount of progesterone receptor isoform A (PR-A) so that it is greater than that of isoform B (PR-B) and administering a therapeutically effective amount of an antiprogestin to the subject, thereby treating the carcinoma.