Patents by Inventor Paolo Bonaldo

Paolo Bonaldo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors
    Patent number: 9694014
    Abstract: Administration of a monoamine oxidase inhibitor is useful in the prevention and treatment of muscle dystrophy. Methods and compositions for inhibiting the production of reactive oxygen species in a muscle cell overproducing reactive oxygen species are provided herein.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: July 4, 2017
    Assignee: Universita Degli Studi di Padova
    Inventors: Paolo Bonaldo, Marcella Canton, Fabio DiLisa, Sara Menazza
  • TREATMENT OF MUSCULAR DYSTROPHIES AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS
    Publication number: 20150290201
    Abstract: Administration of a monoamine oxidase inhibitor is useful in the prevention and treatment of muscle dystrophy. Methods and compositions for inhibiting the production of reactive oxygen species in a muscle cell overproducing reactive oxygen species are provided herein.
    Type: Application
    Filed: July 15, 2013
    Publication date: October 15, 2015
    Inventors: Paolo Bonaldo, Marcella Canton, Fabio DiLisa, Sara Menazza
  • Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors
    Patent number: 8487008
    Abstract: Administration of a monoamine oxidase inhibitor is useful in the prevention and treatment of muscle dystrophy. Methods and compositions for inhibiting the production of reactive oxygen species in a muscle cell overproducing reactive oxygen species are provided herein.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: July 16, 2013
    Assignee: Universita degli Studi di Padova
    Inventors: Paolo Bonaldo, Marcella Canton, Fabio DiLisa, Sara Menazza
  • TREATMENT OF MUSCULAR DYSTROPHIES AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS
    Publication number: 20120329800
    Abstract: Administration of a monoamine oxidase inhibitor is useful in the prevention and treatment of muscle dystrophy. Methods and compositions for inhibiting the production of reactive oxygen species in a muscle cell overproducing reactive oxygen species are provided herein.
    Type: Application
    Filed: June 22, 2011
    Publication date: December 27, 2012
    Inventors: Paolo Bonaldo, Marcella Canton, Fabio DiLisa, Sara Menazza
  • TGF-Beta Modulators and Use Thereof
    Publication number: 20090036382
    Abstract: The present invention relates to molecules preferably of polypeptide nature with negative regulatory activity on the amount or activity of TGF-? through direct interaction with pro-TGF-?, and containing as active region a cysteine-rich polypeptide sequence defined as “EMI domain”, or its subfragments, wherein said “EMI domain” has at least 25% sequence homology to the ID NO2 sequence for pharmaceutical use. Even more preferably said polypeptide sequence consists of the EMI domain of the following proteins: emilin-1, emilin-2 and/or multimerin-2 or their subfragments having a length of at least 6 amino acids, capable of inhibiting the conversion of pro-TGF? to mature TGF? as anti-hypertensive drugs and polypeptides active on the cardiovascular system.
    Type: Application
    Filed: February 1, 2007
    Publication date: February 5, 2009
    Applicants: Universita' Degli Studi Di Padova, Universita' Degli Studi Di Roma "La Sapienza"
    Inventors: Giorgio Bressan, Paolo Bonaldo, Stefano Piccolo, Giuseppe Lembo