Abstract: A vapor compression refrigeration system has a main refrigerant circuit having a primary compressor group, a gas cooler or condenser, an expansion device, a liquid receiver, and at least one evaporator. An emergency circulation duct fluidically connects the liquid receiver to the main circuit to allow a flow of refrigerant from the liquid receiver to the gas cooler. An emergency compressor group in the emergency circulation duct is activatable when pressure inside the liquid receiver or in the duct upstream of the emergency compressor group meets or exceeds a predefined emergency pressure threshold. An uninterruptible power supply powers the emergency compressor group and expansion device during a shutdown of the refrigeration system. When pressure inside the liquid receiver or in the duct upstream of the emergency compressor group equals or exceeds the predefined emergency pressure threshold, an emergency circulation of refrigerant fluid is activated through the emergency circulation duct.

Abstract: A refrigeration plant with multiple evaporation levels, operating according to a vapour compression cycle and including a circuit having a high-pressure branch HP, wherein is arranged at least one heat exchanger, and two or more low-pressure branches, each of which operates at a different evaporation level to serve users having different refrigeration requirements. In each of the low-pressure branches the plant comprises an expansion device, at least one evaporator and a compressor group. At least one evaporator of each low-pressure branch is connected directly to the high-pressure branch. At least a first low-pressure branch comprises a liquid separator fluidically connected: to the evaporator outlet to collect the liquid exiting the evaporator when operating in overfeeding conditions; and to the intake of the compressor group. Such liquid separator is fluidically connected to a second low-pressure branch upstream of the expansion device of such second low-pressure branch through a first connection duct.

Abstract: A vapor compression refrigeration system has a main refrigerant circuit having a primary compressor group, a gas cooler or condenser, an expansion device, a liquid receiver, and at least one evaporator. An emergency circulation duct fluidically connects the liquid receiver to the main circuit to allow a flow of refrigerant from the liquid receiver to the gas cooler. An emergency compressor group in the emergency circulation duct is activatable when pressure inside the liquid receiver or in the duct upstream of the emergency compressor group meets or exceeds a predefined emergency pressure threshold. An uninterruptible power supply powers the emergency compressor group and expansion device during a shutdown of the refrigeration system. When pressure inside the liquid receiver or in the duct upstream of the emergency compressor group equals or exceeds the predefined emergency pressure threshold, an emergency circulation of refrigerant fluid is activated through the emergency circulation duct.

Abstract: The invention relates to a refrigeration plant with multiple evaporation levels, operating according to a vapour compression cycle and comprising a circuit 2 having a high-pressure branch HP, wherein is arranged at least one heat exchanger 10, and two or more low-pressure branches LP1,LP2,LP3, each of which operates at a different evaporation level to serve users having different refrigeration requirements. In each of the low-pressure branches the plant comprises an expansion device 11?,11?,11??, at least one evaporator 12?,12?,12?? and a compressor group 13?,13?,13??. Said at least one evaporator of each low-pressure branch LP1, LP2, LP3 is connected directly to said high-pressure branch HP. At least a first low-pressure branch LP1 comprises a liquid separator 20? that is fluidically connected: —to the evaporator outlet 12? to collect the liquid exiting the evaporator itself in the case in which the latter is operating in overfeeding conditions; and —to the intake of the compressor group 13?.

Abstract: Compounds of formula (I) wherein R, R′, R″, R1, R2, R3, R4, R5, R6, X, Y, m, n, and p have the meanings reported in the description; and their pharmaceutically acceptable salts are described.

Abstract: A compound of Formula (I) ##STR1## or a pharmaceutically acceptable salt thereof, wherein n is an integer between 2 and 6 and R.sub.1 is a methyl group or a group ##STR2## wherein R.sub.2, R.sub.3 and R.sub.4 are independently hydrogen, hydroxy, methoxy, methylsulfonyl, or one of R.sub.2, R.sub.3 and R.sub.4 together with another one of the three substituents forms a --O--CH.sub.2 --O-- bridge. The asterisk marks an asymmetric carbon atom.

Abstract: Compounds of the formula: ##STR1## wherein the variables are as defined in the specification. These compounds are useful in the treatment of arterial hypertension and heart failure, of renal insufficiency, of peripheral arteriopathies and of cerebrovascular insufficiencies.

Abstract: Compounds of formula (I) wherein R.sub.1 and R.sub.2 are independently hydrogen or an optionally branched C.sub.1-4 alkyl group; the asterisk marks an asymmetric carbon atom; and the pharmaceutically acceptable salts thereof, useful in cardiovascular field, are described.

Abstract: Compounds of the formula: ##STR1## wherein R is a hydrogen atom or an OY group; R.sub.1 is a hydrogen atom or in OY' group; R.sub.2 is a hydrogen atom or an OY" group; provided that at lent one among R, R.sub.1 and R.sub.2 is hydrogen but R, R.sub.1, and R.sub.2 are not contemporaneously hydrogen atoms and R.sub.1 and R.sub.2 are not contemporaneously OY' or OY" groups respectively; m is an integer 1 or 2; n is an integer 3 to 8; p is an integer 2, 3, or 4; R.sub.3 is a hydrogen atom or a C.sub.1 -C.sub.4 alkyl; R.sub.4 is a phenyl optionally substituted by halogen atom or a C.sub.1 -C.sub.3 alkyl or alkoxy group or a 5- or 6- membered heteroaryl containing one or more heteroatoms selected from oxygen, nitrogen and sulphur, optionally substituted by halogen atoms, hydroxy groups, C.sub.1 -C.sub.3 alkyl or alkoxy groups; X is CH.sub.2, NH, S, SO, SO.sub.2, CO, CF.sub.2, O and, when R.sub.4 is a 5- or 6- membered heteroaryl, X can be also a single bond. Pharmaceutically acceptable salts are described.

Abstract: Compounds of formula ##STR1## wherein R, R', R", R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X, Y, m, n and p have the meanings reported in the description;and their pharmaceutically acceptable salts are described.The compounds of formula I are useful in the treatment of arterial hypertension and congestive heart failure, of renal failure, of peripheral arteriopathies, of cerebrovascular insufficiencies and of ischemic cardiopathy.

Abstract: A process for the direct and regioselective functionalization of phenothiazine which allows one to introduce an SH group in position 2, said process comprising the sulfination or sulfonation of the phenothiazine N-protected with an alkoxycarbonyl, an alkylsulfonyl or an arylsulfonyl group, the reduction of the produce obtained to give the N-protected 2-mercapto-phenothiazine, and the deprotection of the nitrogen atom. The thus-obtained 2-mercapto-phenothiazine is an important intermediate for the preparation of pharmacological active compounds.

Abstract: A process for the selective dehalogenation in position 5 of the naphthalenic nucleus of compounds of formula ##STR1## (wherein X, X.sub.1 and R have the meanings reported in the description) by treatment with a dehalogenating agent selected among hydrogen sulfide, aliphatic thiols or mixtures thereof in an inert anhydrous solvent at acid pH.