Patents by Inventor Paolo Cozzi

Paolo Cozzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan as platelet aggregation inhibitors
    Patent number: 4588738
    Abstract: Platelet aggregation inhibiting compositions and methods of use containing compounds of the formula ##STR1## where Z completes a bond or is a ##STR2## group; one of R.sub.1 and R.sub.2 is hydroxy and the other is hydrogen or alkyl, or R.sub.1 and R.sub.2, taken together, form an oxo group; and the remaining substituents are as defined in the specification.
    Type: Grant
    Filed: June 1, 1984
    Date of Patent: May 13, 1986
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Pier P. Lovisolo
  • N-Imidazolyl derivatives containing naphthalene or indene nucleus
    Patent number: 4510149
    Abstract: Compounds of the formula (I) ##STR1## wherein the symbol represents a single or a double bond; Z completes a single bond or is a --CH.sub.2 -- group; each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different is(a) hydrogen; hydroxy; halogen; cyano; C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 alkoxy; a C.sub.2 -C.sub.4 acyl or C.sub.2 -C.sub.4 acylamino group; --SR', --N(R') (R"), --CH.sub.2 OR', --COR or --CH.sub.2 COR, wherein R is OR' or --N(R') (R") and each of R' and R", being the same or different, is hydrogen or C.sub.1 -C.sub.6 alkyl; or(b) one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is 5- tetrazolyl or a group selected from --COCH.sub.2 OR', --CH.dbd.C(R')-COR and --X-C(R') (R")-COR, wherein R, R' and R" are as defined above, and X is --O--, --S--, or --NH--, and the others are as defined above under (a);one of R.sub.5 and R.sub.6 is hydrogen and the other is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.
    Type: Grant
    Filed: July 1, 1983
    Date of Patent: April 9, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Germano Carganico, Antonio Pillan, Umberto Branzoli
  • N-Imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan
    Patent number: 4492707
    Abstract: Compounds of the formula ##STR1## where Z completes a bond or is a ##STR2## group; one of R.sub.1 and R.sub.2 is hydroxy and the other is hydrogen or alkyl, or R.sub.1 and R.sub.2, taken together, form an oxo group;and the remaining substituents are as defined in the specification. These compounds possess hypolipaemic properties.
    Type: Grant
    Filed: July 15, 1982
    Date of Patent: January 8, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Pier P. Lovisolo
  • Ethers of substituted hydroxymethylpyrazines
    Patent number: 4406901
    Abstract: Ethers of substituted hydroxymethylpyrazines, such as, for instance, the compound 2-methoxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit elevated lipid-lowering activity, especially anti-lipolytic activity (decrease of plasma-free fatty acids), triglyceride-lowering activity, cholesterol-lowering activity, and plasma-phospholipid-lowering activity.
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: September 27, 1983
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran
    Patent number: 4342775
    Abstract: 3-(1-imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran, such as, for instance, the compound 3-(1-imidazolyl)-2,3-dihydro-4H-1-benzopyran-4-one, are disclosed, as well as method of making same, and pharmaceutical compositions containing same. Also disclosed is a method of using such compounds to inhibit blood platelet aggregation, to increase total serum HDL cholesterol, to increase the ratio between .alpha.-lipoprotein and .beta.-lipoprotein total cholesterol, and/or of reducing total serum cholesterol or serum triglycerides.
    Type: Grant
    Filed: February 12, 1981
    Date of Patent: August 3, 1982
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Nicola Mongelli, Antonio Pillan, Maria Bergamaschi, Pier P. Lovisolo
  • Substituted N-(.beta.-alkoxy-ethyl)-N-(4-phenoxy-benzyl)-dichloro-acetamides and process for their preparation
    Patent number: 4302472
    Abstract: Substituted N-(.beta.-Alkoxy-Ethyl)-N-(4-Phenoxy Benzyl)-Dichoroacetamides are provided for the chemotherapeutic treatment of amebiasis.
    Type: Grant
    Filed: August 1, 1979
    Date of Patent: November 24, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Piero Menchetti, Ivo de Carneri, Franca Trane
  • 2-Hydroxymethyl-pyrazine derivatives and process for their preparation
    Patent number: 4267327
    Abstract: 2-Hydroxymethyl-pyrazine derivatives are disclosed, such as, for instance, the compound 2-hydroxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit an elevated lipid lowering activity, and can be used to control triglyceride and cholesterol levels.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: May 12, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Osvaldo Magni, Leone Bertone, Romano Angelucci, Pier P. Lovisolo