Patents by Inventor Paolo Galiano
Paolo Galiano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11906413Abstract: An apparatus and a corresponding method used, in the field of medical analysis, to determine erythrocyte sedimentation rate, as well as other connected parameters.Type: GrantFiled: April 17, 2019Date of Patent: February 20, 2024Assignee: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20230340618Abstract: A disposable cartridge suitable to carry out molecular biology tests starting from biological samples positive for microorganisms includes at least one specific reaction mixture for RT-PCR (Real Time Polymerase Chain Reaction) suitable for typing particular microorganisms and/or for providing information on relative resistance to antimicrobial and antifungal drugs, a panel that includes a plurality of cartridges and a method to identify at least one microorganism and/or its resistance to antimicrobial or antifungal drugs responsible for a systemic inflammatory state.Type: ApplicationFiled: March 18, 2021Publication date: October 26, 2023Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20220364985Abstract: Method to identify microorganisms in a sample, by evaluating the vibrational profile.Type: ApplicationFiled: July 30, 2019Publication date: November 17, 2022Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Patent number: 11326198Abstract: A method to classify and identify microorganisms using the FTIR ATR technique.Type: GrantFiled: January 31, 2019Date of Patent: May 10, 2022Assignee: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20210116349Abstract: An apparatus and a corresponding method used, in the field of medical analysis, to determine erythrocyte sedimentation rate, as well as other connected parameters.Type: ApplicationFiled: April 17, 2019Publication date: April 22, 2021Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20200354766Abstract: Method to classify and identify microorganisms that provides to classify and identity microorganisms using the FTIR ATR technique.Type: ApplicationFiled: January 31, 2019Publication date: November 12, 2020Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20200208191Abstract: A method to detect bacteria in a biological sample in order to determine if the biological sample contains tuberculous mycobacteria or non-tuberculous mycobacteria, said tuberculous mycobacteria being detected by analyzing a set of measurements consisting of a plurality of light scattering measurements by means of algorithms making use of neural networks.Type: ApplicationFiled: July 18, 2018Publication date: July 2, 2020Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20190212349Abstract: An integrated apparatus for diagnostic analyses includes a support structure; a first refrigerated container an analysis area in which microplates are positioned and having receptacles or wells for receiving a primary sample; a samples removal and delivery unit to remove a primary sample from test tubes and deliver it into the wells; a temperature control area containing the primary samples; and a robotic head configured to interact with said samples removal and delivery unit so as to transfer the primary samples taken from the test tubes to the temperature control area and configured to insert, into each of the wells, the sample where a bacterial growth has been identified, an antibiotic in liquid form according to a choice at the discretion of the operator directed as a function of the type of species identified.Type: ApplicationFiled: July 4, 2017Publication date: July 11, 2019Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Publication number: 20180348181Abstract: Method and corresponding detection unit to detect bacterial activity in a biological sample, in particular, but not only, blood samples contained in a test tube with a stopper.Type: ApplicationFiled: November 28, 2016Publication date: December 6, 2018Applicant: ALIFAX S.R.L.Inventor: Paolo Galiano
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Patent number: 9494507Abstract: An apparatus to determine the blood sedimentation rate and other parameters connected thereto, carried out by emitting, by means of emitter means, a beam of radiations which passes through a sample being examined, and by detecting, by means of receiver means, the beam of radiations after they have passed through said sample, comprising a reading chamber associated to at least a tube connected to a feed of the sample to be analyzed. Said reading chamber is at least partly transparent to radiations in a certain range of wavelengths, and has at least a substantially rectilinear segment of reduced size into which the sample to be analyzed is introduced. The reading chamber consists of a tube made of plastic material, or glass, defining a capillary channel coupled to said tube in fluidic continuity.Type: GrantFiled: July 19, 2013Date of Patent: November 15, 2016Assignee: ALIFAX HOLDING SPAInventor: Paolo Galiano
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Publication number: 20160002696Abstract: Method to identify bacterial classes in a biological sample, in particular a urine sample, that provides to carry out an analysis by means of Gas Chromatography-Mass Spectrometry (GC/MS) of the volatile components, such as metabolites and catabolites, of the sample in order to identify a graphic plot characteristic of a specific bacterial class.Type: ApplicationFiled: February 20, 2014Publication date: January 7, 2016Applicant: ALIFAX HOLDING SPAInventor: Paolo Galiano
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Publication number: 20150300937Abstract: An apparatus to determine the blood sedimentation rate and other parameters connected thereto, carried out by emitting, by means of emitter means, a beam of radiations which passes through a sample being examined, and by detecting, by means of receiver means, the beam of radiations after they have passed through said sample, comprising a reading chamber associated to at least a tube connected to a feed of the sample to be analyzed. Said reading chamber is at least partly transparent to radiations in a certain range of wavelengths, and has at least a substantially rectilinear segment of reduced size into which the sample to be analyzed is introduced. The reading chamber consists of a tube made of plastic material, or glass, defining a capillary channel coupled to said tube in fluidic continuity.Type: ApplicationFiled: July 19, 2013Publication date: October 22, 2015Applicant: ALIFAX HOLDING SPAInventor: Paolo Galiano
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Patent number: 8927258Abstract: An integrated device for diagnostic analyzes used to verify the presence of bacteria in at least a biological sample mixed with a eugonic culture medium in liquid form, to classify at least the type of bacteria, and to test a series of antibiotics, selected from a group of characteristic antibiotics at least for the type of bacteria identified, identifying those effective to determine the antibiotic therapy. The device comprises, inside an integrated structure, first containing means provided with containing elements in which the biological samples to be analyzed are distributed, second containing means comprising recipients or micro-plates thermostated with wells containing a eugonic culture medium in liquid form in which a first fraction of the biological samples to be analyzed is dispensed, and a first recipient and second recipients or plates with a relative first well and second wells in which a further fraction of the biological samples which resulted positive to the analysis is dispensed.Type: GrantFiled: February 24, 2010Date of Patent: January 6, 2015Assignee: Alifax Holding SpAInventors: Paolo Galiano, Gian Piero Spezzotti
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Patent number: 8679739Abstract: A method for diagnostic analysis, in particular to identify pathogens, such as viruses, bacteria or other micro-organisms present in a biological sample, comprises a first step of measuring and continuously monitoring the turbidity and/or the concentration of the pathogens, by means of an instrumental reading technique, of a liquid culture medium into which the sample to be analyzed has been inoculated and in which the replication of the pathogens possibly present occurs, said measuring and monitoring being carried out dynamically during the replication of the pathogens growing in the culture medium; and a second step of identifying the pathogens, carried out by taking at least an aliquot of the liquid culture medium containing the biological sample directly obtained from the first step, which has reached a desired value of turbidity according to a standardized value scale, such as the McFarland turbidity scale, and/or of concentration of the pathogens, and using said aliquot directly in mass spectrophotometrType: GrantFiled: January 13, 2011Date of Patent: March 25, 2014Assignee: Alifax Holding SpAInventor: Paolo Galiano
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Patent number: 8425843Abstract: Integrated apparatus and method for hematological analyses, wherein the apparatus, comprises, arranged substantially in line and integrated substantially in a single machine, a device (14) of the optical type to detect substantially instantaneously the speed of blood sedimentation (ESR) by measuring the optical density, or absorbance, of the blood sample, and a measuring assembly (18) with a cell-counter function or suchlike.Type: GrantFiled: July 13, 2007Date of Patent: April 23, 2013Assignee: Alifax Holding SpAInventors: Alfredo Ciotti, Paolo Galiano
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Publication number: 20130022962Abstract: A method for diagnostic analyses, in particular to identify pathogens, such as viruses, bacteria or other micro-organisms present in a biological sample, comprises a first step of measuring and continuously monitoring the turbidity and/or the concentration of the pathogens, by means of an instrumental reading technique, of a liquid culture medium into which the sample to be analyzed has been inoculated and in which the replication of the pathogens possibly present occurs, said measuring and monitoring being carried out dynamically during the replication of the pathogens growing in the culture medium; and a second step of identifying the pathogens, carried out by taking at least an aliquot of the liquid culture medium containing the biological sample directly obtained from the first step, which has reached a desired value of turbidity according to a standardized value scale, such as the McFarland turbidity scale, and/or of concentration of the pathogens, and using said aliquot directly in mass spectrophotometrType: ApplicationFiled: January 13, 2011Publication date: January 24, 2013Applicant: ALIFAX HOLDING SPAInventor: Paolo Galiano
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Publication number: 20120252134Abstract: A test tube (10) for taking and containing a sample for diagnostic analyses comprises a containing body (12) with an end edge (11a) that delimits an aperture (11), a tubular member (22) protruding toward the outside with respect to said end edge (11a) and connected with the inside of said containing body (12) through said aperture (11) for the passage of the sample, suction means (13, 115) made in a single piece with said containing body (12) and selectively drivable to take in a desired volume of sample through said tubular member (22), a closing device (14) constrained to said end edge (11a) and comprising a closing element (18) selectively movable toward a closing position located above said end edge (11a) in order to close said aperture (11). The tubular member (22) is conformed to be selectively removable so as to allow the passage of the closing element (18) to the superimposed position, in order to close the aperture (11).Type: ApplicationFiled: December 15, 2010Publication date: October 4, 2012Applicant: ALIFAX HOLDING SPAInventor: Paolo Galiano
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Publication number: 20110307183Abstract: A method for the bacterial investigation of a biological sample, which provides to carry out a light scattering reading in order to determine the turbidity according to the McFarland standard of a suspension formed from a liquid culture means or eugonic medium in which the biological sample is inoculated, and in which the turbidity is continuously measured directly from the suspension of the sample analyzed during the growth step of the bacteria, until a determined threshold of turbidity is reached expressed according to the McFarland standard.Type: ApplicationFiled: February 24, 2010Publication date: December 15, 2011Applicant: ALIFAX HOLDING SPAInventors: Paolo Galiano, Alessandro Mansutti
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Publication number: 20110306087Abstract: An apparatus to analyze a biological sample contained in a container, comprising an examining device able to perform an optical measurement on the biological sample, based on light-scattering technology, at least of the bacterial growth in the biological sample. The examining device is provided with emitter means able to emit a first light beam toward the container of the biological sample and sensor means able to detect at least a light beam diffused from the container of the biological sample and to transmit a relative signal, correlated to the light beam diffused, to a control unit which is able to process, directly or indirectly, the signal in order to verify at least the possible bacterial growth in the biological sample. The container is disposed along a determinate lying plane and comprises at least a containing micro-element able to contain at least a part of the biological sample and inside which a liquid culture ground is provided so as to allow bacterial growth in the biological sample.Type: ApplicationFiled: February 24, 2010Publication date: December 15, 2011Applicant: ALIFAX HOLDING SPAInventors: Paolo Galiano, Alessandro Mansutti
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Publication number: 20110306032Abstract: An integrated device for diagnostic analyses used to verify the presence of bacteria in at least a biological sample mixed with a eugonic culture medium in liquid form, to classify at least the type of bacteria, and to test a series of antibiotics, selected from a group of characteristic antibiotics at least for the type of bacteria identified, identifying those effective to determine the antibiotic therapy. The device comprises, inside an integrated structure, first containing means provided with containing elements in which the biological samples to be analyzed are distributed, second containing means comprising recipients or micro-plates thermostated with wells containing a eugonic culture medium in liquid form in which a first fraction of the biological samples to be analyzed is dispensed, and a first recipient and second recipients or plates with a relative first well and second wells in which a further fraction of the biological samples which resulted positive to the analysis is dispensed.Type: ApplicationFiled: February 24, 2010Publication date: December 15, 2011Applicant: ALIFAX HOLDING SPAInventors: Paolo Galiano, Gian Piero Spezzotti