Patents by Inventor Paolo Galiano

Paolo Galiano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11906413
    Abstract: An apparatus and a corresponding method used, in the field of medical analysis, to determine erythrocyte sedimentation rate, as well as other connected parameters.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: February 20, 2024
    Assignee: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20230340618
    Abstract: A disposable cartridge suitable to carry out molecular biology tests starting from biological samples positive for microorganisms includes at least one specific reaction mixture for RT-PCR (Real Time Polymerase Chain Reaction) suitable for typing particular microorganisms and/or for providing information on relative resistance to antimicrobial and antifungal drugs, a panel that includes a plurality of cartridges and a method to identify at least one microorganism and/or its resistance to antimicrobial or antifungal drugs responsible for a systemic inflammatory state.
    Type: Application
    Filed: March 18, 2021
    Publication date: October 26, 2023
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20220364985
    Abstract: Method to identify microorganisms in a sample, by evaluating the vibrational profile.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 17, 2022
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Patent number: 11326198
    Abstract: A method to classify and identify microorganisms using the FTIR ATR technique.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: May 10, 2022
    Assignee: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20210116349
    Abstract: An apparatus and a corresponding method used, in the field of medical analysis, to determine erythrocyte sedimentation rate, as well as other connected parameters.
    Type: Application
    Filed: April 17, 2019
    Publication date: April 22, 2021
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20200354766
    Abstract: Method to classify and identify microorganisms that provides to classify and identity microorganisms using the FTIR ATR technique.
    Type: Application
    Filed: January 31, 2019
    Publication date: November 12, 2020
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20200208191
    Abstract: A method to detect bacteria in a biological sample in order to determine if the biological sample contains tuberculous mycobacteria or non-tuberculous mycobacteria, said tuberculous mycobacteria being detected by analyzing a set of measurements consisting of a plurality of light scattering measurements by means of algorithms making use of neural networks.
    Type: Application
    Filed: July 18, 2018
    Publication date: July 2, 2020
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20190212349
    Abstract: An integrated apparatus for diagnostic analyses includes a support structure; a first refrigerated container an analysis area in which microplates are positioned and having receptacles or wells for receiving a primary sample; a samples removal and delivery unit to remove a primary sample from test tubes and deliver it into the wells; a temperature control area containing the primary samples; and a robotic head configured to interact with said samples removal and delivery unit so as to transfer the primary samples taken from the test tubes to the temperature control area and configured to insert, into each of the wells, the sample where a bacterial growth has been identified, an antibiotic in liquid form according to a choice at the discretion of the operator directed as a function of the type of species identified.
    Type: Application
    Filed: July 4, 2017
    Publication date: July 11, 2019
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Publication number: 20180348181
    Abstract: Method and corresponding detection unit to detect bacterial activity in a biological sample, in particular, but not only, blood samples contained in a test tube with a stopper.
    Type: Application
    Filed: November 28, 2016
    Publication date: December 6, 2018
    Applicant: ALIFAX S.R.L.
    Inventor: Paolo Galiano
  • Patent number: 9494507
    Abstract: An apparatus to determine the blood sedimentation rate and other parameters connected thereto, carried out by emitting, by means of emitter means, a beam of radiations which passes through a sample being examined, and by detecting, by means of receiver means, the beam of radiations after they have passed through said sample, comprising a reading chamber associated to at least a tube connected to a feed of the sample to be analyzed. Said reading chamber is at least partly transparent to radiations in a certain range of wavelengths, and has at least a substantially rectilinear segment of reduced size into which the sample to be analyzed is introduced. The reading chamber consists of a tube made of plastic material, or glass, defining a capillary channel coupled to said tube in fluidic continuity.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: November 15, 2016
    Assignee: ALIFAX HOLDING SPA
    Inventor: Paolo Galiano
  • Publication number: 20160002696
    Abstract: Method to identify bacterial classes in a biological sample, in particular a urine sample, that provides to carry out an analysis by means of Gas Chromatography-Mass Spectrometry (GC/MS) of the volatile components, such as metabolites and catabolites, of the sample in order to identify a graphic plot characteristic of a specific bacterial class.
    Type: Application
    Filed: February 20, 2014
    Publication date: January 7, 2016
    Applicant: ALIFAX HOLDING SPA
    Inventor: Paolo Galiano
  • Publication number: 20150300937
    Abstract: An apparatus to determine the blood sedimentation rate and other parameters connected thereto, carried out by emitting, by means of emitter means, a beam of radiations which passes through a sample being examined, and by detecting, by means of receiver means, the beam of radiations after they have passed through said sample, comprising a reading chamber associated to at least a tube connected to a feed of the sample to be analyzed. Said reading chamber is at least partly transparent to radiations in a certain range of wavelengths, and has at least a substantially rectilinear segment of reduced size into which the sample to be analyzed is introduced. The reading chamber consists of a tube made of plastic material, or glass, defining a capillary channel coupled to said tube in fluidic continuity.
    Type: Application
    Filed: July 19, 2013
    Publication date: October 22, 2015
    Applicant: ALIFAX HOLDING SPA
    Inventor: Paolo Galiano
  • Patent number: 8927258
    Abstract: An integrated device for diagnostic analyzes used to verify the presence of bacteria in at least a biological sample mixed with a eugonic culture medium in liquid form, to classify at least the type of bacteria, and to test a series of antibiotics, selected from a group of characteristic antibiotics at least for the type of bacteria identified, identifying those effective to determine the antibiotic therapy. The device comprises, inside an integrated structure, first containing means provided with containing elements in which the biological samples to be analyzed are distributed, second containing means comprising recipients or micro-plates thermostated with wells containing a eugonic culture medium in liquid form in which a first fraction of the biological samples to be analyzed is dispensed, and a first recipient and second recipients or plates with a relative first well and second wells in which a further fraction of the biological samples which resulted positive to the analysis is dispensed.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: January 6, 2015
    Assignee: Alifax Holding SpA
    Inventors: Paolo Galiano, Gian Piero Spezzotti
  • Patent number: 8679739
    Abstract: A method for diagnostic analysis, in particular to identify pathogens, such as viruses, bacteria or other micro-organisms present in a biological sample, comprises a first step of measuring and continuously monitoring the turbidity and/or the concentration of the pathogens, by means of an instrumental reading technique, of a liquid culture medium into which the sample to be analyzed has been inoculated and in which the replication of the pathogens possibly present occurs, said measuring and monitoring being carried out dynamically during the replication of the pathogens growing in the culture medium; and a second step of identifying the pathogens, carried out by taking at least an aliquot of the liquid culture medium containing the biological sample directly obtained from the first step, which has reached a desired value of turbidity according to a standardized value scale, such as the McFarland turbidity scale, and/or of concentration of the pathogens, and using said aliquot directly in mass spectrophotometr
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: March 25, 2014
    Assignee: Alifax Holding SpA
    Inventor: Paolo Galiano
  • Patent number: 8425843
    Abstract: Integrated apparatus and method for hematological analyses, wherein the apparatus, comprises, arranged substantially in line and integrated substantially in a single machine, a device (14) of the optical type to detect substantially instantaneously the speed of blood sedimentation (ESR) by measuring the optical density, or absorbance, of the blood sample, and a measuring assembly (18) with a cell-counter function or suchlike.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: April 23, 2013
    Assignee: Alifax Holding SpA
    Inventors: Alfredo Ciotti, Paolo Galiano
  • Publication number: 20130022962
    Abstract: A method for diagnostic analyses, in particular to identify pathogens, such as viruses, bacteria or other micro-organisms present in a biological sample, comprises a first step of measuring and continuously monitoring the turbidity and/or the concentration of the pathogens, by means of an instrumental reading technique, of a liquid culture medium into which the sample to be analyzed has been inoculated and in which the replication of the pathogens possibly present occurs, said measuring and monitoring being carried out dynamically during the replication of the pathogens growing in the culture medium; and a second step of identifying the pathogens, carried out by taking at least an aliquot of the liquid culture medium containing the biological sample directly obtained from the first step, which has reached a desired value of turbidity according to a standardized value scale, such as the McFarland turbidity scale, and/or of concentration of the pathogens, and using said aliquot directly in mass spectrophotometr
    Type: Application
    Filed: January 13, 2011
    Publication date: January 24, 2013
    Applicant: ALIFAX HOLDING SPA
    Inventor: Paolo Galiano
  • Publication number: 20120252134
    Abstract: A test tube (10) for taking and containing a sample for diagnostic analyses comprises a containing body (12) with an end edge (11a) that delimits an aperture (11), a tubular member (22) protruding toward the outside with respect to said end edge (11a) and connected with the inside of said containing body (12) through said aperture (11) for the passage of the sample, suction means (13, 115) made in a single piece with said containing body (12) and selectively drivable to take in a desired volume of sample through said tubular member (22), a closing device (14) constrained to said end edge (11a) and comprising a closing element (18) selectively movable toward a closing position located above said end edge (11a) in order to close said aperture (11). The tubular member (22) is conformed to be selectively removable so as to allow the passage of the closing element (18) to the superimposed position, in order to close the aperture (11).
    Type: Application
    Filed: December 15, 2010
    Publication date: October 4, 2012
    Applicant: ALIFAX HOLDING SPA
    Inventor: Paolo Galiano
  • Publication number: 20110306087
    Abstract: An apparatus to analyze a biological sample contained in a container, comprising an examining device able to perform an optical measurement on the biological sample, based on light-scattering technology, at least of the bacterial growth in the biological sample. The examining device is provided with emitter means able to emit a first light beam toward the container of the biological sample and sensor means able to detect at least a light beam diffused from the container of the biological sample and to transmit a relative signal, correlated to the light beam diffused, to a control unit which is able to process, directly or indirectly, the signal in order to verify at least the possible bacterial growth in the biological sample. The container is disposed along a determinate lying plane and comprises at least a containing micro-element able to contain at least a part of the biological sample and inside which a liquid culture ground is provided so as to allow bacterial growth in the biological sample.
    Type: Application
    Filed: February 24, 2010
    Publication date: December 15, 2011
    Applicant: ALIFAX HOLDING SPA
    Inventors: Paolo Galiano, Alessandro Mansutti
  • Publication number: 20110307183
    Abstract: A method for the bacterial investigation of a biological sample, which provides to carry out a light scattering reading in order to determine the turbidity according to the McFarland standard of a suspension formed from a liquid culture means or eugonic medium in which the biological sample is inoculated, and in which the turbidity is continuously measured directly from the suspension of the sample analyzed during the growth step of the bacteria, until a determined threshold of turbidity is reached expressed according to the McFarland standard.
    Type: Application
    Filed: February 24, 2010
    Publication date: December 15, 2011
    Applicant: ALIFAX HOLDING SPA
    Inventors: Paolo Galiano, Alessandro Mansutti
  • Publication number: 20110306032
    Abstract: An integrated device for diagnostic analyses used to verify the presence of bacteria in at least a biological sample mixed with a eugonic culture medium in liquid form, to classify at least the type of bacteria, and to test a series of antibiotics, selected from a group of characteristic antibiotics at least for the type of bacteria identified, identifying those effective to determine the antibiotic therapy. The device comprises, inside an integrated structure, first containing means provided with containing elements in which the biological samples to be analyzed are distributed, second containing means comprising recipients or micro-plates thermostated with wells containing a eugonic culture medium in liquid form in which a first fraction of the biological samples to be analyzed is dispensed, and a first recipient and second recipients or plates with a relative first well and second wells in which a further fraction of the biological samples which resulted positive to the analysis is dispensed.
    Type: Application
    Filed: February 24, 2010
    Publication date: December 15, 2011
    Applicant: ALIFAX HOLDING SPA
    Inventors: Paolo Galiano, Gian Piero Spezzotti