Patents by Inventor Paolo Lazzari
Paolo Lazzari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20090081123Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, wherein Z? is as defined below; a substituent having an hydroxyl function of formula —CH(OH)-Z?; an amide substituent of formula —C(O)—NH-T?.Type: ApplicationFiled: December 8, 2008Publication date: March 26, 2009Applicant: CeNeRx BioPharmaInventors: Paolo LAZZARI, Stefania RUIU, Gerard Aime PINNA, Gabriele MURINEDDU
-
Patent number: 7485730Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, a substituent having an hydroxyl function of formula —CH(OH)-Z?; and an amide substituent of formula —C(O)—NH-T?.Type: GrantFiled: May 23, 2005Date of Patent: February 3, 2009Assignee: Neuroscienze Pharmaness S.C. A R.L.Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Aime Pinna, Gabriele Murineddu
-
Patent number: 7122608Abstract: VDF polymerization process, optionally modified with small amounts of one or more fluoro-containing comonomers, carried out in the presence of a microemulsion comprising a (per) fluoropolyether having neutral end groups, having number average molecular weight between 400 and 3000, and a surfactant based on perfluoropolyethers with salified acid end groups, said surfactant having a number molecular weight Mn comprised between 400–600 and having a distribution of molecular weights such that fractions having a number average molecular weight higher than 700 are not present, or are in amount less than 5% by weight.Type: GrantFiled: June 30, 1997Date of Patent: October 17, 2006Assignee: Solvay Solexis, S.p.A.Inventors: Giulio Brinati, Paolo Lazzari, Vincenzo Arcella
-
Publication number: 20050282798Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, wherein Z? is as defined below; a substituent having an hydroxyl function of formula —CH(OH)-Z?; an amide substituent of formula —C(O)—NH-T?.Type: ApplicationFiled: May 23, 2005Publication date: December 22, 2005Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Pinna, Gabriele Murineddu
-
Publication number: 20050261281Abstract: Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from: C1-C10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; A is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R? wherein v is equal to 1 or 2; R? is as defined in the present application; a ketone group of formula —C(O)-Z?, wherein Z? is as defined in the present application; a substituent having an hydroxyl function of formula —CH(OH)-Z?, Z? being as defined in the present application; Description of the industrial invention in the name of: NEUROSCIENZE S.c. a r.l., of Italian nationality, with head office in Cagliari, via Palabanda 9.Type: ApplicationFiled: May 23, 2005Publication date: November 24, 2005Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Pinna, Gabriele Murineddu
-
Publication number: 20020091212Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula:Type: ApplicationFiled: November 8, 1999Publication date: July 11, 2002Inventors: JULIO A. ABUSLEME, PAOLO LAZZARI
-
Patent number: 6417390Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula: Rf—[L—(OCHR1—CHR2)m—OZ)]i wherein: i is equal to 1 or 2; m is an integer comprised between 4 and 60; L can be chosen between: —(CFY—CO—O)pR′— and —(CFY—CO—NH)pR′— wherein is an integer equal to 0 or to 1; Y═F, CF3; R′=alkylic radical C1-C5, linear or branched when possible; R1, R2 can be both H or the former H and the latter CH3; Z can be H, alkyl radical C1-C3, linear or branched when possible; or (CH2)nOH with n an integer from 1 to 6; Rf is a perfluoroalkylic radical or a perfluoropolyether radical, having a number average molecular weight comprised between 250 and 1500.Type: GrantFiled: November 8, 1999Date of Patent: July 9, 2002Assignee: Ausimont S.p.A.Inventors: Julio A. Abusleme, Paolo Lazzari
-
Patent number: 6100325Abstract: Dispersions, obtained starting from a system formed by a (per)fluorinated polymer in polar solvent, comprising at least:0.1-30% by weight of a polytetrafluoroethylene or of tetrafluoroethylene copolymers with other ethylenically unsaturated, totally or partially fluorinated, monomers;50-99% by weight of fluorinated liquid;0.01-5% by weight of surfactant selected from carboxylic acids with PFPE chain and nonionic surfactants having a perfluoroalkylic or perfluoropolyether chain with a oxyalkylenic repeating unit number lower than or equal to 6;polar solvent (water and/or alcohol) complement to 100; weight ratio lower than that of the initial system containing the (per)fluoropolymer used to prepare the dispersion.Type: GrantFiled: July 30, 1998Date of Patent: August 8, 2000Assignee: Ausimont S.p.A.Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti
-
Patent number: 6025307Abstract: Fluorinated greases comprising (by weight):15%-50% polytetrafluoroethylene or tetrafluoroethylene copolymers with other ethylenically unsaturated monomers;30%-84.5% perfluoropolyether oil having a viscosity comprised between 20 and 4000 cSt at 20.degree. C.;0.5%-10% surfactant or dispersant having perfluoropolyether or perfluoroalkylic chain;0%-10% of an anticorrosion and/or antiwear additive, such that the (per)fluoropolymer particles based on TFE or their aggregates have average sizes lower than the micron and show improved diameter WEAR values.Type: GrantFiled: March 19, 1998Date of Patent: February 15, 2000Assignee: Ausimont S.p.A.Inventors: Alba Chittofrati, Paolo Lazzari, Luca Caluso
-
Patent number: 6013712Abstract: Dispersions comprising at least:0.1-30% by weight of a polytetrafluoroethylene or tetrafluoroethylene copolymers with other ethylenically unsaturated monomers;50-99% by weight of fluorinated liquid;polar solvent (water and/or alcohol) complement to 100;0.01-5% by weight of surfactant selected from:(a) nonionic hydrogenated or(b) fluorinated, having a perfluoropolyether or perfluoroalkylic chain, both of ionic and non ionic type, selected from the following classes:A') mono and dicarboxylic acid salts;B') sulphonic acid salts;C') phosphoric mono and diesters and their mixtures, as such or salified, optionally containing amounts of triesters lower than 15% by moles;D') nonionic surfactants formed by fluorinated and polyoxyalkylenic chains with a number of oxyalkylenic repeating units higher than 6;E') cationic surfactants having one or more fluorinated hydrophobic chains.Type: GrantFiled: July 30, 1998Date of Patent: January 11, 2000Assignee: Ausimont S.p.A.Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti
-
Patent number: 6013747Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula:R.sub.f --[L--(OCHR.sub.1 --CHR.sub.2).sub.m --OZ)].sub.iwherein:i is equal to 1 or 2;m is an integer comprised between 4 and 60;L can be chosen between: --(CFY--CO--O).sub.p R'-- and --(CFY--CO--NH).sub.p R'--wherein p is an integer equal to 0 or to 1;Y=F, CF.sub.3 ; R'=alkylic radical C.sub.1 -C.sub.5, linear or branched when possible;R.sub.1, R.sub.2 can be both H or the former H and the latter CH.sub.3 ;Z can be H, alkyl radical C.sub.1 -C.sub.3, linear or branched when possible; or (CH.sub.2).sub.n OH with n an integer from 1 to 6;R.sub.f is a perfluoroalkylic radical or a perfluoropolyether radical, having a number average molecular weight comprised between 250 and 1500.Type: GrantFiled: July 7, 1997Date of Patent: January 11, 2000Assignee: Ausimont, S.p.A.Inventors: Julio A. Abusleme, Paolo Lazzari
-
Patent number: 5942572Abstract: Non-ionic compound having the general formula:R.sub.f --L--(OCHR.sub.1 --CHR.sub.2).sub.n --O--L'--R.sub.f' (I)wherein:n is an integer comprised between 4 and 60, preferably between 8 and 30;L and L', equal to or different from each other, can be selected from:--(CFY--CO--O).sub.p R'-- and --(CFY--CO--NH).sub.p R'--wherein: p is 0 or 1; Y can be F or CF.sub.3 ; R' is an alkylic radical C.sub.1 -C.sub.5,R.sub.1, R.sub.2 can be both H or the former one H and the latter CH.sub.3.R.sub.f and R.sub.f', equal to or different from each other, can be perfluoropolyethereal radicals having a number average molecular weight comprised between 250 and 1500, preferably between 400 and 1000; and its use as thickener of aqueous latexes based on fluoropolymers.Type: GrantFiled: July 7, 1997Date of Patent: August 24, 1999Assignee: Ausimont S.p.A.Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti