Patents by Inventor Paolo Lazzari

Paolo Lazzari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090081123
    Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, wherein Z? is as defined below; a substituent having an hydroxyl function of formula —CH(OH)-Z?; an amide substituent of formula —C(O)—NH-T?.
    Type: Application
    Filed: December 8, 2008
    Publication date: March 26, 2009
    Applicant: CeNeRx BioPharma
    Inventors: Paolo LAZZARI, Stefania RUIU, Gerard Aime PINNA, Gabriele MURINEDDU
  • Patent number: 7485730
    Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, a substituent having an hydroxyl function of formula —CH(OH)-Z?; and an amide substituent of formula —C(O)—NH-T?.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: February 3, 2009
    Assignee: Neuroscienze Pharmaness S.C. A R.L.
    Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Aime Pinna, Gabriele Murineddu
  • Patent number: 7122608
    Abstract: VDF polymerization process, optionally modified with small amounts of one or more fluoro-containing comonomers, carried out in the presence of a microemulsion comprising a (per) fluoropolyether having neutral end groups, having number average molecular weight between 400 and 3000, and a surfactant based on perfluoropolyethers with salified acid end groups, said surfactant having a number molecular weight Mn comprised between 400–600 and having a distribution of molecular weights such that fractions having a number average molecular weight higher than 700 are not present, or are in amount less than 5% by weight.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: October 17, 2006
    Assignee: Solvay Solexis, S.p.A.
    Inventors: Giulio Brinati, Paolo Lazzari, Vincenzo Arcella
  • Publication number: 20050282798
    Abstract: Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: A represents a group selected from one of the following: (CH2)t—, —(CH2)—S(O)z—, or —S(O)z—(CH2)—, B is a heteroaryl, optionally substituted; R is a group selected from the following: alkyl, aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; R? is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R?, a ketonic group of formula —C(O)-Z?, wherein Z? is as defined below; a substituent having an hydroxyl function of formula —CH(OH)-Z?; an amide substituent of formula —C(O)—NH-T?.
    Type: Application
    Filed: May 23, 2005
    Publication date: December 22, 2005
    Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Pinna, Gabriele Murineddu
  • Publication number: 20050261281
    Abstract: Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from: C1-C10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; A is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R? wherein v is equal to 1 or 2; R? is as defined in the present application; a ketone group of formula —C(O)-Z?, wherein Z? is as defined in the present application; a substituent having an hydroxyl function of formula —CH(OH)-Z?, Z? being as defined in the present application; Description of the industrial invention in the name of: NEUROSCIENZE S.c. a r.l., of Italian nationality, with head office in Cagliari, via Palabanda 9.
    Type: Application
    Filed: May 23, 2005
    Publication date: November 24, 2005
    Inventors: Paolo Lazzari, Stefania Ruiu, Gerard Pinna, Gabriele Murineddu
  • Publication number: 20020091212
    Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula:
    Type: Application
    Filed: November 8, 1999
    Publication date: July 11, 2002
    Inventors: JULIO A. ABUSLEME, PAOLO LAZZARI
  • Patent number: 6417390
    Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula: Rf—[L—(OCHR1—CHR2)m—OZ)]i wherein: i is equal to 1 or 2; m is an integer comprised between 4 and 60; L can be chosen between: —(CFY—CO—O)pR′— and —(CFY—CO—NH)pR′— wherein is an integer equal to 0 or to 1; Y═F, CF3; R′=alkylic radical C1-C5, linear or branched when possible; R1, R2 can be both H or the former H and the latter CH3; Z can be H, alkyl radical C1-C3, linear or branched when possible; or (CH2)nOH with n an integer from 1 to 6; Rf is a perfluoroalkylic radical or a perfluoropolyether radical, having a number average molecular weight comprised between 250 and 1500.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: July 9, 2002
    Assignee: Ausimont S.p.A.
    Inventors: Julio A. Abusleme, Paolo Lazzari
  • Patent number: 6100325
    Abstract: Dispersions, obtained starting from a system formed by a (per)fluorinated polymer in polar solvent, comprising at least:0.1-30% by weight of a polytetrafluoroethylene or of tetrafluoroethylene copolymers with other ethylenically unsaturated, totally or partially fluorinated, monomers;50-99% by weight of fluorinated liquid;0.01-5% by weight of surfactant selected from carboxylic acids with PFPE chain and nonionic surfactants having a perfluoroalkylic or perfluoropolyether chain with a oxyalkylenic repeating unit number lower than or equal to 6;polar solvent (water and/or alcohol) complement to 100; weight ratio lower than that of the initial system containing the (per)fluoropolymer used to prepare the dispersion.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: August 8, 2000
    Assignee: Ausimont S.p.A.
    Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti
  • Patent number: 6025307
    Abstract: Fluorinated greases comprising (by weight):15%-50% polytetrafluoroethylene or tetrafluoroethylene copolymers with other ethylenically unsaturated monomers;30%-84.5% perfluoropolyether oil having a viscosity comprised between 20 and 4000 cSt at 20.degree. C.;0.5%-10% surfactant or dispersant having perfluoropolyether or perfluoroalkylic chain;0%-10% of an anticorrosion and/or antiwear additive, such that the (per)fluoropolymer particles based on TFE or their aggregates have average sizes lower than the micron and show improved diameter WEAR values.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: February 15, 2000
    Assignee: Ausimont S.p.A.
    Inventors: Alba Chittofrati, Paolo Lazzari, Luca Caluso
  • Patent number: 6013712
    Abstract: Dispersions comprising at least:0.1-30% by weight of a polytetrafluoroethylene or tetrafluoroethylene copolymers with other ethylenically unsaturated monomers;50-99% by weight of fluorinated liquid;polar solvent (water and/or alcohol) complement to 100;0.01-5% by weight of surfactant selected from:(a) nonionic hydrogenated or(b) fluorinated, having a perfluoropolyether or perfluoroalkylic chain, both of ionic and non ionic type, selected from the following classes:A') mono and dicarboxylic acid salts;B') sulphonic acid salts;C') phosphoric mono and diesters and their mixtures, as such or salified, optionally containing amounts of triesters lower than 15% by moles;D') nonionic surfactants formed by fluorinated and polyoxyalkylenic chains with a number of oxyalkylenic repeating units higher than 6;E') cationic surfactants having one or more fluorinated hydrophobic chains.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: January 11, 2000
    Assignee: Ausimont S.p.A.
    Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti
  • Patent number: 6013747
    Abstract: Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula:R.sub.f --[L--(OCHR.sub.1 --CHR.sub.2).sub.m --OZ)].sub.iwherein:i is equal to 1 or 2;m is an integer comprised between 4 and 60;L can be chosen between: --(CFY--CO--O).sub.p R'-- and --(CFY--CO--NH).sub.p R'--wherein p is an integer equal to 0 or to 1;Y=F, CF.sub.3 ; R'=alkylic radical C.sub.1 -C.sub.5, linear or branched when possible;R.sub.1, R.sub.2 can be both H or the former H and the latter CH.sub.3 ;Z can be H, alkyl radical C.sub.1 -C.sub.3, linear or branched when possible; or (CH.sub.2).sub.n OH with n an integer from 1 to 6;R.sub.f is a perfluoroalkylic radical or a perfluoropolyether radical, having a number average molecular weight comprised between 250 and 1500.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: January 11, 2000
    Assignee: Ausimont, S.p.A.
    Inventors: Julio A. Abusleme, Paolo Lazzari
  • Patent number: 5942572
    Abstract: Non-ionic compound having the general formula:R.sub.f --L--(OCHR.sub.1 --CHR.sub.2).sub.n --O--L'--R.sub.f' (I)wherein:n is an integer comprised between 4 and 60, preferably between 8 and 30;L and L', equal to or different from each other, can be selected from:--(CFY--CO--O).sub.p R'-- and --(CFY--CO--NH).sub.p R'--wherein: p is 0 or 1; Y can be F or CF.sub.3 ; R' is an alkylic radical C.sub.1 -C.sub.5,R.sub.1, R.sub.2 can be both H or the former one H and the latter CH.sub.3.R.sub.f and R.sub.f', equal to or different from each other, can be perfluoropolyethereal radicals having a number average molecular weight comprised between 250 and 1500, preferably between 400 and 1000; and its use as thickener of aqueous latexes based on fluoropolymers.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: August 24, 1999
    Assignee: Ausimont S.p.A.
    Inventors: Alba Chittofrati, Paolo Lazzari, Daria Lenti