Abstract: A method for the spatially-resolved probing of bio logical tissue (102) comprises the steps of emitting, by means of at least one light source (106), a series of light pulses into the tissue and of measuring, by means of a plurality of light detectors (108), a plurality of time-resolved responses to the light pulses scattered from the tissue. The measurement is carried out with a temporal resolution better than 20 ps. A plurality of first responses is in response to light pulses at a first illumination band and is measured at a plurality of first detection bands. The first detection bands differ from each other and from the first illumination band in order to detect inelastic scattering. A plurality of second responses is in response to light pulses at a second illumination band and is measured at a second detection band. The second detection band overlaps with the second illumination band in order to detect elastic scatting. Time of flight analysis of both responses allows to e.g.

Abstract: The device comprises an array (8) of cells (10), with each cell having a single-photon avalanche diode (12) and a quenching circuit (14). Each cell (10) further comprises a first analog output (A) as well as a digital output (D). A latch (20) is provided for buffering a pulse generated by the diode (12) and selectively feeding it to the digital output (D). The cells (10) are arranged in rows and columns, and the outputs (A, D) are fed to analog and digital bus lines (40, 42) for off-array analog and digital signal processing. A data switch (54) and a shift register (58) are provided for serializing various measurement results detected by the device.