Patents by Inventor Paolo Paolucci

Paolo Paolucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified effector cell (or chimeric receptor) for treating disialoganglioside G-expressing neoplasia
    Patent number: 10647997
    Abstract: A modified effector cell includes a non-reversibly produced vector-encoded anti-GD2-BB-? chimeric receptor for use in disialoganglioside GD2-expressing neoplasia, which is inserted in the cell, to obtain an effector cell that stably produces the anti-GD2-BB-? chimeric receptor, the chimeric receptor having two distinct mutually fused portions, i.e. an intra-cytoplasmic portion and an extra-cytoplasmic portion.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: May 12, 2020
    Assignee: St. Jude Children's Research Hospital, Inc.
    Inventors: Massimo Dominici, Sara Caldrer, Maria Carlotta Spano, Paolo Paolucci, Marco Bestagno, Dario Campana
  • Method of obtaining a population of cells
    Patent number: 10273457
    Abstract: A method of obtaining stromal progenitor cells (SPC) from subcutaneous adipose tissue by incubation of a very small volume of the subcutaneous adipose tissue in an enzyme solution produces SPC that are usable in medical applications based on autologous SPC even on individuals having a body mass index lower than 18.5.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: April 30, 2019
    Inventors: Massimo Dominici, Luigi Cafarelli, Elena Veronesi, Maria Serena Piccinno, Paolo Paolucci, Giorgio De Santis, Pierfranco Conte
  • Modified Effector Cell (or Chimeric Receptor) for Treating Disialoganglioside GD2-Expressing Neoplasia
    Publication number: 20140302608
    Abstract: A modified effector cell includes a non-reversibly produced vector-encoded anti-GD2-BB-? chimeric receptor for use in disialoganglioside GD2-expressing neoplasia, which is inserted in the cell, to obtain an effector cell that stably produces the anti-GD2-BB-? chimeric receptor, the chimeric receptor having two distinct mutually fused portions, i.e. an intra-cytoplasmic portion and an extra-cytoplasmic portion.
    Type: Application
    Filed: October 25, 2012
    Publication date: October 9, 2014
    Inventors: Massimo Dominici, Sara Caldrer, Maria Carlotta Spano, Paolo Paolucci, Marco Bestagno, Dario Campana
  • Method of obtaining a population of cells
    Publication number: 20140302605
    Abstract: A method of obtaining stromal progenitor cells (SPC) from subcutaneous adipose tissue by incubation of a very small volume of the subcutaneous adipose tissue in an enzyme solution produces SPC that are usable in medical applications based on autologous SPC even on individuals having a body mass index lower than 18.5.
    Type: Application
    Filed: June 19, 2014
    Publication date: October 9, 2014
    Inventors: Massimo Dominici, Luigi Cafarelli, Elena Veronesi, Maria Serena Piccinno, Paolo Paolucci, Giorgio De Santis, Pierfranco Conte
  • Method for obtaining a population of stromal progenitor cells
    Publication number: 20130130381
    Abstract: The present invention relates to a technique for obtaining stromal progenitor cells (SPC) from adipose tissue (AT) using incubation of very small volumes of AT with an enzyme solution, that can obtain SPC for autologous SPC-based medical applications to a greater number of individuals, possibly having a lower Body Mass Index (B.M.I), i.e. lower than 18.5.
    Type: Application
    Filed: April 14, 2011
    Publication date: May 23, 2013
    Inventors: Massimo Dominici, Luigi Cafarelli, Elena Veronesi, Maria Serena Piccinno, Paolo Paolucci, Giorgio De Santis, Pierfranco Conte