Patents by Inventor Paolo Rovatti
Paolo Rovatti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240123127Abstract: A control unit of an apparatus for extracorporeal blood treatment is configured to perform a control procedure comprising: calculating parameter control values to be set during a time interval after the instant in which the control is made, on the basis of actual values and of prescription values of variation in blood volume, ultrafiltration flow rate, concentration of sodium and/or potassium and heart rate or variation of heart rate of the patient; imposing the parameter control values during the time interval consecutive to the instant in which the control is made such that the actual values of the variation in blood volume track the prescription values of the variation in blood volume over a predetermined treatment time and the actual values of the heart rate or variation of heart rate track the prescription values of the heart rate or variation of heart rate over the predetermined treatment time.Type: ApplicationFiled: February 10, 2022Publication date: April 18, 2024Inventors: Paolo Rovatti, Alessandro Surace
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Patent number: 11883571Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.Type: GrantFiled: April 15, 2020Date of Patent: January 30, 2024Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Publication number: 20230330315Abstract: An apparatus for extracorporeal blood treatment for chronic therapy comprises a nutritional bag (33) containing a nutritional solution, a weighing device (36) configured to determine a weight (W) of the nutritional bag (33), a nutritional line (34) for infusing the nutritional solution into either a blood return line (7) or into the patient vascular system. An ultrafiltration device (30) is configured to achieve a fluid removal from the patient through a semi- permeable membrane (5) of a filtration unit (2) and a sensor (31, 32) is configured to determine an ultrafiltration rate (UFR). A control unit (100) connected to the ultrafiltration device (30), to the weighing device (33) and to the sensor (31, 32) is programmed for receiving a patient prescription and for controlling the ultrafiltration device (30) to achieve the patient prescription based on the weight (W) and on ultrafiltration rate (UFR).Type: ApplicationFiled: April 9, 2021Publication date: October 19, 2023Inventor: Paolo Rovatti
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Patent number: 11701463Abstract: There is provided an IV infusion set comprising a patient access configured to connect to a vascular system of a patient, a source of medical fluid, an infusion line having one first end configured to connect to the source of medical fluid and one opposite second end configured to deliver the medical fluid towards the patient access, an infusion apparatus arranged on the infusion line, a sensor configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line, and a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal. The IV infusion set further comprises a compliance element configured to attenuate pressure variations of medical fluid the infusion line, and a resistance element configured to reflect pressure waves moving along the infusion line.Type: GrantFiled: December 21, 2018Date of Patent: July 18, 2023Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Paolo Rovatti, Mariano Ruffo, David Stefani, Elena Grandi
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Publication number: 20230014488Abstract: An extracorporeal blood treatment apparatus comprises: a blood treatment device (2) comprising a blood chamber (3) and a fluid chamber (4) separated from one another by a semipermeable membrane (5); an extracorporeal blood circuit (17) comprising a blood withdrawal line (6) connected to an inlet port (3a) of the blood chamber (3) and a blood return line (7) connected to an outlet port (3b) of the blood chamber (3); a blood pump (21) configured to be coupled to the blood withdrawal line (6); a hydraulic circuit (100) connectable to the fluid chamber (4), wherein the hydraulic circuit (100) comprises a fluid preparation device (9) connected to a water network (14) and configured to dilute concentrates in water to prepare a treatment fluid; a control unit (12) connected to the preparation device (9) and to the blood pump (21).Type: ApplicationFiled: September 20, 2022Publication date: January 19, 2023Inventors: Paolo Rovatti, Katty Ferrari
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Patent number: 11471576Abstract: An extracorporeal blood treatment apparatus comprises: a blood treatment device (2) comprising a blood chamber (3) and a fluid chamber (4) separated from one another by a semipermeable membrane (5); an extracorporeal blood circuit (17) comprising a blood withdrawal line (6) connected to an inlet port (3a) of the blood chamber (3) and a blood return line (7) connected to an outlet port (3b) of the blood chamber (3); a blood pump (21) configured to be coupled to the blood withdrawal line (6); a hydraulic circuit (100) connectable to the fluid chamber (4), wherein the hydraulic circuit (100) comprises a fluid preparation device (9) connected to a water network (14) and configured to dilute concentrates in water to prepare a treatment fluid; a control unit (12) connected to the preparation device (9) and to the blood pump (21).Type: GrantFiled: July 5, 2018Date of Patent: October 18, 2022Assignee: Gambio Lundia ABInventors: Paolo Rovatti, Katty Ferrari
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Patent number: 11426501Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: GrantFiled: October 27, 2017Date of Patent: August 30, 2022Assignee: Gambro Lundia ABInventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Publication number: 20220249025Abstract: Non-invasive heartbeat sensor for determining a heart rate in a conduit of an extracorporeal blood treatment apparatus, comprising one source for directing an optical signal towards the blood flowing in the segment; one detector for receiving an optical informative signal comprising the signal emitted by said source after passing the blood, and emitting respective output signal; a controller receiving the respective output signal and retrieving a heartbeat frequency and a heart rate value, based on the output signal, wherein the informative signal is altered by flow perturbation of the blood partially generated by the flow impulses originated by the heart.Type: ApplicationFiled: September 18, 2020Publication date: August 11, 2022Inventors: Paolo Rovatti, Mariano Ruffo, David Stefani
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Patent number: 11383012Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: GrantFiled: October 26, 2017Date of Patent: July 12, 2022Assignee: Gambro Lundia ABInventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Publication number: 20220143284Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line. A control unit (10) is configured to calculate values of a parameter relating to treatment effectiveness based on measures of the conductivity in the spent dialysate line. An upstream variation of the value of the characteristic (Cdin) is caused in the fresh treatment liquid with respect to a prescription baseline (Cdset) thereby causing a corresponding and timely delayed downstream variation of the same characteristic (Cdout) in the spent liquid flowing in the spent dialysate line (13). An amplitude (?Cin) and/or a duration over time (?T) of the upstream variation are/is computed as a function of the flow rate (Qdial) of the fresh treatment liquid in a preparation line (19) or of the parameter correlated to the flow rate (Qdial).Type: ApplicationFiled: January 23, 2020Publication date: May 12, 2022Inventors: Paolo Rovatti, Marco Salsa
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Publication number: 20220096719Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit connected to a blood circuit and to a dialysate circuit, a preparation device for preparing and regulating the composition of the dialysis fluid; a control unit is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line at a set point based on the physician prescription; starting from the initial patient plasma conductivity, estimated at the beginning of the treatment, and based on the target plasma conductivity/sodium concentration which is equivalent to the dialysate conductivity/sodium concentration prescribed, the control unit determines the minimum constant gradient between dialysis fluid and plasma conductivity/concentration to be maintained during treatment to achieve the conductivity/concentration target in the patient plasma at the end of the session.Type: ApplicationFiled: December 27, 2019Publication date: March 31, 2022Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI
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Publication number: 20210369932Abstract: A mobile dialysis therapy cart includes a top shelf; a cycler compartment positioned below the top shelf, the cycler compartment sized and shaped to house an APD cycler; a fluid bag management compartment sized and shaped to house at least two fluid bags; a drain compartment positioned below the fluid bag management compartment; and a plurality of wheels. The cart may include a heating device associated with the fluid bag management compartment and/or a sanitizing light source for sanitizing a location of a disposable set associated with the fluid bags.Type: ApplicationFiled: May 26, 2021Publication date: December 2, 2021Inventors: Matthew Muller, Tom Westberg, James W. Kendall, Carlos Corrales, Carpani Michela, Paolo Rovatti, Luca Vinci, Mauro Suffritti
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Publication number: 20210015990Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a treatment unit (2), a blood withdrawal line (6), a blood return line (7), a preparation line (19) and a spent dialysate line (13); a non-invasive blood volume sensor (50) for determining an additional property of blood is active on a tube segment (61) of the blood withdrawal line or of the blood return line; the sensor includes one source (53) for directing a signal towards the blood, a plurality of detectors (57) for receiving the signal, and a controller (65) receiving the output signals from the detectors (57) and determining a blood volume variation and a value of sodium concentration in the blood (Napl) both based on the output signals. A process of determining at least one parameter and on property of blood circulating an extracorporeal blood circuit is also disclosed.Type: ApplicationFiled: March 20, 2019Publication date: January 21, 2021Inventors: Paolo ROVATTI, Enrico RAVAGLI, Stefano SEVERI
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Publication number: 20210001043Abstract: There is provided an IV infusion set comprising a patient access configured to connect to a vascular system of a patient, a source of medical fluid, an infusion line having one first end configured to connect to the source of medical fluid and one opposite second end configured to deliver the medical fluid towards the patient access, an infusion apparatus arranged on the infusion line, a sensor configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line, and a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal. The IV infusion set further comprises a compliance element configured to attenuate pressure variations of medical fluid the infusion line, and a resistance element configured to reflect pressure waves moving along the infusion line.Type: ApplicationFiled: December 21, 2018Publication date: January 7, 2021Inventors: Paolo ROVATTI, Mariano RUFFO, David STEFANI, Elena GRANDI
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Publication number: 20200390954Abstract: An extracorporeal blood treatment apparatus comprises: a blood treatment device (2) comprising a blood chamber (3) and a fluid chamber (4) separated from one another by a semipermeable membrane (5); an extracorporeal blood circuit (17) comprising a blood withdrawal line (6) connected to an inlet port (3a) of the blood chamber (3) and a blood return line (7) connected to an outlet port (3b) of the blood chamber (3); a blood pump (21) configured to be coupled to the blood withdrawal line (6); a hydraulic circuit (100) connectable to the fluid chamber (4), wherein the hydraulic circuit (100) comprises a fluid preparation device (9) connected to a water network (14) and configured to dilute concentrates in water to prepare a treatment fluid; a control unit (12) connected to the preparation device (9) and to the blood pump (21).Type: ApplicationFiled: July 5, 2018Publication date: December 17, 2020Inventors: Paolo ROVATTI, Katty FERRARI
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Publication number: 20200237990Abstract: An extracorporeal blood treatment apparatus includes a filtration unit (2) connected to a blood circuit (17) and a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e. spent dialysis fluid); a control unit (12) configured for setting a sodium concentration in the dialysis fluid and after setting the dialysis fluid at the initial set point, circulating the dialysis fluid and blood through the filtration unit (2), measuring an initial conductivity value of the dialysate at the beginning of the treatment, and calculating, based on the measured initial conductivity value and on the corresponding conductivity value of the dialysis fluid, the value of the initial plasma conductivity, said circulating of the dialysis fluid up to the calculating of the initial plasma conductivity performed by maintaining the dialysis fluid conductivity substantially constant.Type: ApplicationFiled: April 15, 2020Publication date: July 30, 2020Inventors: Paolo ROVATTI, Alessandro SURACE, Carlo Alberto LODI, Anders WALLENBORG, Anders NILSSON, Kristian SOLEM, Jan STERNBY, Thomas HERTZ
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Patent number: 10646632Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: GrantFiled: May 23, 2016Date of Patent: May 12, 2020Assignee: GAMBRO LUNDIA ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz
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Publication number: 20190374697Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid, and a sensor (11) for measuring conductivity of the dialysate (i.e.Type: ApplicationFiled: October 27, 2017Publication date: December 12, 2019Inventors: Anders Wallenborg, Anders Nilsson, Kristian Solem, Thomas Hertz, Paolo Rovatti, Carlo Alberto Lodi, Alessandro Surace, Jan Sternby
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Patent number: 10485912Abstract: A method of operating an extracorporeal blood treatment includes, prior to commencing an extracorporeal blood treatment, reading from a storage device (4a, 5a) stored values of a patient-specific prescription parameter. These stored values relate to a sequence of previous extracorporeal blood treatments. In addition, the method includes processing the stored values of the parameter read from the storage device (4a, 5a) according to a predetermined algorithm to determine a current value of the patient-specific prescription parameter. The current value is then available for the subsequent extracorporeal blood treatment.Type: GrantFiled: December 10, 2014Date of Patent: November 26, 2019Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace
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Patent number: 10434236Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.Type: GrantFiled: May 23, 2016Date of Patent: October 8, 2019Assignee: Gambro Lundia ABInventors: Paolo Rovatti, Alessandro Surace, Carlo Alberto Lodi, Anders Wallenborg, Anders Nilsson, Kristian Solem, Jan Sternby, Thomas Hertz