Patents by Inventor Paolo Schiavini

Paolo Schiavini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITOR OF INDOLEAMINE 2,3-DIOXYGENASE-1 AND METHODS OF MANUFACTURE AND USE THEREOF
    Publication number: 20230265079
    Abstract: Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of IDO, syntheses, and uses thereof are provided.
    Type: Application
    Filed: January 12, 2023
    Publication date: August 24, 2023
    Inventors: Donald WEAVER, Michael G. BRANT, Stephanie WOHNIG, Fan WU, Jake GOODWIN-TINDALL, Autumn MEEK, Paolo SCHIAVINI
  • Inhibitor of indoleamine 2,3-dioxygenase-1 and methods of manufacture and use thereof
    Patent number: 11572354
    Abstract: Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of Formula (Ia) and (Ib) of IDO, their synthesis, and uses thereof are provided.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: February 7, 2023
    Assignee: University Health Network
    Inventors: Donald Weaver, Michael G. Brant, Stephanie Wohnig, Fan Wu, Jake Goodwin-Tindall, Autumn Meek, Paolo Schiavini