Patents by Inventor Paolo Spicar-Mihalic

Paolo Spicar-Mihalic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and device for rapid parallel microfluidic molecular affinity assays
    Patent number: 9138743
    Abstract: Disclosed are methods and devices for rapid parallel molecular affinity assays performed in a microfluidic environment. The invention exploits hydrodynamic addressing to provide simultaneous performance of multiple assays in parallel using a minimal sample volume flowing through a single channel.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: September 22, 2015
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Paul Yager, Turgut Fettah Kosar, Michael Wai-Haung Look, Afshin Mashadi-Hossein, Katherine McKenzie, Kjell E. Nelson, Paolo Spicar-Mihalic, Dean Stevens, Rahber Thariani
  • METHOD AND DEVICE FOR RAPID PARALLEL MICROFLUIDIC MOLECULAR AFFINITY ASSAYS
    Publication number: 20120171698
    Abstract: Disclosed are methods and devices for rapid parallel molecular affinity assays performed in a microfluidic environment. The invention exploits hydrodynamic addressing to provide simultaneous performance of multiple assays in parallel using a minimal sample volume flowing through a single channel.
    Type: Application
    Filed: January 5, 2012
    Publication date: July 5, 2012
    Applicant: University of Washington
    Inventors: Paul Yager, Turgut Fettah Kosar, Michael Wai-Haung Look, Afshin Mashadi-Hossein, Katherine McKenzie, Kjell E. Nelson, Paolo Spicar-Mihalic, Dean Stevens, Rahber Thariani
  • Method and device for rapid parallel microfluidic molecular affinity assays
    Patent number: 8101403
    Abstract: Disclosed are methods and devices for rapid parallel molecular affinity assays performed in a microfluidic environment. The invention exploits hydrodynamic addressing to provide simultaneous performance of multiple assays in parallel using a minimal sample volume flowing through a single channel.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: January 24, 2012
    Assignee: University of Washington
    Inventors: Paul Yager, Turgut Fettah Kosar, Michael Wai-Haung Look, Afshin Mashadi-Hossein, Katherine McKenzie, Kjell E. Nelson, Paolo Spicar-Mihalic, Dean Y. Stevens, Rahber Thariani
  • MICROFLUIDIC SYSTEMS INCORPORATING FLOW-THROUGH MEMBRANES
    Publication number: 20110151479
    Abstract: Disclosed is a flow-through membrane assay that takes advantage of a high surface area and rapid transport while allowing individual control over flow rates and times for each step of a multi-step assay. A microfluidic card features channels in communication with a porous membrane, channels on either side of membrane to allow transverse flow across the membrane, capturing a labeled target from the sample by flowing the sample across the membrane, or capturing a target from the sample followed by flowing a reagent containing a label that binds to the target. Fluid can be pushed or pulled through the assay membrane by external control. Air near the membrane is managed by diverting air between fluids to a channel upstream of the assay membrane, venting air between fluids through a hydrophobic membrane upstream of the assay membrane, and/or by venting trapped air through a hydrophobic membrane downstream of the assay membrane.
    Type: Application
    Filed: August 25, 2009
    Publication date: June 23, 2011
    Applicant: University of Washington
    Inventors: Dean Y. Stevens, Lisa K. Lafleur, Berry R. Lutz, Paolo Spicar-Mihalic, Paul Yager
  • METHOD AND DEVICE FOR RAPID PARALLEL MICROFLUIDIC MOLECULAR AFFINITY ASSAYS
    Publication number: 20100081216
    Abstract: Disclosed are methods and devices for rapid parallel molecular affinity assays performed in a microfluidic environment. The invention exploits hydrodynamic addressing to provide simultaneous performance of multiple assays in parallel using a minimal sample volume flowing through a single channel.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 1, 2010
    Applicant: Univeristy of Washington
    Inventors: Paul Yager, Turgut Fettah Kosar, Michael Wai-Haung Look, Afshin Mashadi-Hossein, Katherine McKenzie, Kjell E. Nelson, Paolo Spicar-Mihalic, Dean Y. Stevens, Rahber Thariani