Patents by Inventor Paolo VINCETTI

Paolo VINCETTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USING HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS
    Publication number: 20230159560
    Abstract: The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5D”). The compounds have a general Formula I. wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
    Type: Application
    Filed: November 18, 2022
    Publication date: May 25, 2023
    Inventors: Jennifer R. ALLEN, Michela BELTRANI, Matthew P. BOURBEAU, Teodora P. DAMYANOVA, Iain LINGARD, Ana E. MINATTI, Paolo Vincetti
  • Heterocyclic compounds as Delta-5 desaturase inhibitors and methods of use
    Patent number: 11512097
    Abstract: The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5D”). The compounds have a general Formula I wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: November 29, 2022
    Assignee: AMGEN INC.
    Inventors: Jennifer R. Allen, Michela Beltrani, Matthew P. Bourbeau, Teodora P. Damyanova, Iain Lingard, Ana E. Minatti, Paolo Vincetti
  • FUSED TETRAZOLES AS LRRK2 INHIBITORS
    Publication number: 20210261553
    Abstract: The present invention is directed to fused tetrazoles of formula (IA) which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
    Type: Application
    Filed: May 14, 2019
    Publication date: August 26, 2021
    Inventors: Albert W. Garofalo, Daniele Andreotti, Silvia Bernardi, Elena Serra, Marco Migliore, Fabio Maria Sabbatini, Claudia Beato, Paolo Vincetti, Federica Budassi
  • HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE
    Publication number: 20210221824
    Abstract: The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5D”). The compounds have a general Formula I wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
    Type: Application
    Filed: March 16, 2021
    Publication date: July 22, 2021
    Inventors: Jennifer R. ALLEN, Michela BELTRANI, Matthew P. BOURBEAU, Teodora P. DAMYANOVA, Iain LINGARD, Ana E. MINATTI, Paolo VINCETTI
  • HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE
    Publication number: 20210188874
    Abstract: The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5D”). The compounds have a general Formula I wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
    Type: Application
    Filed: November 24, 2020
    Publication date: June 24, 2021
    Inventors: Jennifer R. ALLEN, Michela BELTRANI, Matthew P. BOURBEAU, Teodora P. DAMYANOVA, Iain LINGARD, Ana E. MINATTI, Paolo VINCETTI