Patents by Inventor Par Holmberg

Par Holmberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10370382
    Abstract: There is provided a novel process for the preparation of a compound of formula (I), wherein R1 is as described in the description, by demethylation of a corresponding O-methyl derivative.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: August 6, 2019
    Assignee: Cambrex Charles City, Inc.
    Inventors: Pär Holmberg, Michael Robert Tracey, Zhiming Eric Dong
  • Publication number: 20180354961
    Abstract: There is provided a novel process for the preparation of a compound of formula (I), wherein R1 is as described in the description, by demethylation of a corresponding O-methyl derivative.
    Type: Application
    Filed: July 26, 2016
    Publication date: December 13, 2018
    Applicant: Cambrex Charles City, Inc.
    Inventors: Pär Holmberg, Michael Robert Tracey, Zhiming Eric Dong
  • Publication number: 20180218449
    Abstract: One aspect of our invention is a bundle rule that could make demand and/or supply of different packages more independent, which would simplify the bidding process, the verification that bids comply with a bidding format, clearing of the auction and presentation of information to traders. A second aspect is that bundling can be automatically updated with regard to auction relevant information before the auction starts or during the auction process. Several aspects of our invention can be combined in an exemplary design. Aspects of our invention can be implemented in computer systems.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 2, 2018
    Inventors: Par Holmberg, Keith Ruddell, Bert Willems
  • Patent number: 9981978
    Abstract: There is provided a novel process for the preparation of a compound of formula I, wherein R1, R2 and R3 are as described in the description, by conversion of a corresponding allylic alcohol.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: May 29, 2018
    Assignee: Cambrex Charles City, Inc.
    Inventors: Michael Tracey, Pär Holmberg, Belén Lindberg Martín Matute, Antonio Bermejo Gómez, Jan-Erling Bäckvall
  • Patent number: 9580439
    Abstract: The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: February 28, 2017
    Assignee: The Scripps Research Institute
    Inventors: Congxin Liang, Marcel Koenig, Yuanjun He, Par Holmberg
  • Publication number: 20160168159
    Abstract: There is provided a novel process for the preparation of a compound of formula I, wherein R1, R2 and R3 are as described in the description, by conversion of a corresponding allylic alcohol.
    Type: Application
    Filed: July 23, 2014
    Publication date: June 16, 2016
    Inventors: Michael Tracey, Pär Holmberg
  • Patent number: 8962862
    Abstract: There is provided a novel process for the preparation of a compound of formula (I), (Formula (I)). There is also provided novel processes to intermediates of the compound of formula (I), as well as novel intermediates themselves.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: February 24, 2015
    Assignee: Cambrex Karlskoga AB
    Inventors: Lars Eklund, Lars Hansson, Tommy Lundholm, Pär Holmberg, Margus Eek
  • Publication number: 20140187789
    Abstract: There is provided a novel process for the preparation of a compound of formula (I), (Formula (I)). There is also provided novel processes to intermediates of the compound of formula (I), as well as novel intermediates themselves.
    Type: Application
    Filed: July 20, 2012
    Publication date: July 3, 2014
    Applicant: CAMBREX KARLSKOGA AB
    Inventors: Lars Eklund, Lars Hansson, Tommy Lundholm, Pär Holmberg, Margus Eek
  • Publication number: 20130281443
    Abstract: The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions.
    Type: Application
    Filed: June 19, 2013
    Publication date: October 24, 2013
    Applicant: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Congxin Liang, Marcel Koenig, Yuanjun He, Par Holmberg
  • Patent number: 8501763
    Abstract: The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: August 6, 2013
    Assignee: The Scripps Research Institute
    Inventors: Congxin Liang, Marcel Koenig, Yuanjun He, Par Holmberg
  • Publication number: 20110046121
    Abstract: The invention provides inhibitors of focal adhesion kinase, an enzyme involved in the attachment of the cytoskeleton of a cell to an extracellular matrix, which has been implicated in processes such as cell migration, cell proliferation, and cell survival. The inhibitors are derivatives of a 5-substituted 2,4-diaminopyridine wherein the substituents are as defined herein. The invention also provides a method of using the inhibitors in treatment of cancer, and methods of preparation of the inhibitors by use of coupling reactions.
    Type: Application
    Filed: March 10, 2008
    Publication date: February 24, 2011
    Applicant: The Scripps Research Institute
    Inventors: Congxin Liang, Marcel Koenig, Yuanjun He, Par Holmberg
  • Patent number: 7046492
    Abstract: A power transformer/inductor includes at least one winding. The winding is made of a high voltage cable that includes an electric conductor, and around the electric conductor is arranged a first semiconducting layer, around the first semiconducting layer is an insulating layer, and around the insulating layer is a second semiconducting layer. The second semiconducting layer is directly earthed at both ends of the winding and furthermore at least at two points per turn of every winding such that one or more points are indirectly earthed.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: May 16, 2006
    Assignee: ABB AB
    Inventors: Udo Fromm, Sven Hornfeldt, Par Holmberg, Gunnar Kylander, Li Ming, Mats Leijon
  • Patent number: 6995646
    Abstract: A power or regulating transformer with voltage regulator includes regulating windings made of a flexible conductor having an electric field containing mechanism that forces the electric field due to the current in the winding to be contained within the flexible conductor. Since virtually no electric field is to be found outside the flexible conductor of the regulating winding, the regulating winding may be formed without having to consider the electric field distribution, thus providing for a transformer with a favorable regulating winding design.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: February 7, 2006
    Assignee: ABB AB
    Inventors: Udo Fromm, Par Holmberg, Albert Jaksts, Mats Leijon, Christian Sasse, Thorsten Schutte
  • Patent number: 6970063
    Abstract: The present invention relates to a power transformer/inductor comprising at least one winding. The windings are designed by means of a high-voltage cable, comprising an electric conductor, and around the conductor there is arranged a first semiconducting layer, around the first semiconducting layer there is arranged an insulating layer and around the insulating layer there is arranged a second semiconducting layer. The second semiconducting layer is earthed at or in the vicinity of both ends (261, 262; 281, 282) of each winding and furthermore one point between both ends (261, 262; 281, 282) is directly earthed.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: November 29, 2005
    Assignee: ABB AB
    Inventors: Udo Fromm, Sven Hornfeldt, Par Holmberg, Gunnar Kylander, Li Ming, Mats Leijon
  • Publication number: 20050099258
    Abstract: A power transformer/inductor includes at least one winding. The winding is made of a high voltage cable that includes an electric conductor, and around the electric conductor is arranged a first semiconducting layer, around the first semiconducting layer is an insulating layer, and around the insulating layer is a second semiconducting layer. The second semiconducting layer is directly earthed at both ends of the winding and furthermore at least at two points per turn of every winding such that one or more points are indirectly earthed.
    Type: Application
    Filed: December 20, 2004
    Publication date: May 12, 2005
    Applicant: ASEA BROWN BOVERI AB
    Inventors: Udo Fromm, Sven Hornfeldt, Par Holmberg, Gunnar Kylander, Li Ming, Mats Leijon
  • Patent number: 6885273
    Abstract: A distributed air gap material for a induction device in power systems for minimizing fringe losses, mechanical losses and noise in the core The distributed air gap material occupies a selected portion of the core and is formed of a finely divided magnetic material in a matrix of a dielectric material particles. The air gap material has a zone of transition in which the permeability values vary within the air gap material.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: April 26, 2005
    Assignee: ABB AB
    Inventors: Pan Min, Li Ming, Rongsheng Liu, Mikael Dahlgren, Par Holmberg, Gunnar Russberg, Christian Sasse, Svante Söderholm
  • Patent number: 6867674
    Abstract: A power transformer having at least one high voltage winding and one low voltage winding. Each of the windings includes at least one current-carrying conductor, a first layer having semiconducting properties provided around said conductor, a solid insulating layer provided around said first layer, and a second layer having semiconducting properties provided around said insulating layer. The windings are intermixed such that turns of the high voltage winding are mixed with turns of the low voltage winding.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: March 15, 2005
    Assignee: Asea Brown Boveri AB
    Inventors: Thorsten Schutte, Par Holmberg, Jan Brangefalt, Christian Sasse, Peter Carstensen
  • Patent number: 6801421
    Abstract: A high power static electromagnetic device with a flux path, a main winding and one or more regulation windings surrounding portions of the flux path. A control device is coupled to the flux path for selectively admitting the flux therein. In an exemplary embodiment, multiple flux paths are selectively turned on and off for including and excluding the regulation windings from the circuit. The windings may be formed of a magnetically permeable, field-confining insulating cable.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: October 5, 2004
    Assignee: ABB AB
    Inventors: Christian Sasse, Mats Leijon, Gunnar Russberg, Udo Fromm, Par Holmberg
  • Publication number: 20030030529
    Abstract: A distributed air gap material for a induction device in power systems for minimizing fringe losses, mechanical losses and noise in the core The distributed air gap material occupies a selected portion of the core and is formed of a finely divided magnetic material in a matrix of a dielectric material particles. The air gap material has a zone of transition in which the permeability values vary within the air gap material.
    Type: Application
    Filed: February 14, 2002
    Publication date: February 13, 2003
    Inventors: Pan Min, Li Ming, Rongsheng Liu, Mikael Dahlgren, Par Holmberg, Gunnar Russberg, Christian Sasse, Svante Soderholm