Patents by Inventor Parameswara Meda Reddy

Parameswara Meda Reddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotide pairs for multiplexed binding assays
    Patent number: 7195875
    Abstract: The invention is an oligonucleotide-based assay system and kit useful for sorting, detecting, and identifying analytes. The system utilizes complementary oligonucleotide pairs in which one oligonucleotide of each pair is immobilized to a solid substrate and the other oligonucleotide has an analyte binding agent attached to it. The different oligonucleotide pairs hybridize at substantially the same rate, have substantially the same Tm, have nucleotide sequences designed to minimize cross-hybridization between different pairs, and hybridize together relatively rapidly at ambient temperatures without detectable cross-hybridization.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: March 27, 2007
    Assignee: Beckman Coulter, Inc.
    Inventors: Daniel A. Keys, Parameswara Meda Reddy, Jackie S. Bodnar, Firdous Farooqui
  • Efficient synthesis of protein-oligonucleotide conjugates
    Patent number: 6942972
    Abstract: The present invention relates to an improved method for forming a protein-oligonucleotide conjugate. The method is particularly amenable for forming antibody-oligonucleotide conjugates. The invention further concerns the conjugate molecules produced using such improved methods.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: September 13, 2005
    Assignee: Beckman Coulter, Inc.
    Inventors: Firdous Farooqui, Parameswara Meda Reddy
  • Oligonucleotide pairs for multiplexed binding assays
    Publication number: 20040209261
    Abstract: The invention is an oligonucleotide-based assay system and kit useful for sorting, detecting, and identifying analytes. The system utilizes complementary oligonucleotide pairs in which one oligonucleotide of each pair is immobilized to a solid substrate and the other oligonucleotide has an analyte binding agent attached to it. The different oligonucleotide pairs hybridize at substantially the same rate, have substantially the same Tm, have nucleotide sequences designed to minimize cross-hybridization between different pairs, and hybridize together relatively rapidly at ambient temperatures without detectable cross-hybridization.
    Type: Application
    Filed: April 18, 2003
    Publication date: October 21, 2004
    Inventors: Daniel A. Keys, Parameswara Meda Reddy, Jackie S. Bodnar, Firdous Farooqui
  • Efficient synthesis of protein-oligonucleotide conjugates
    Publication number: 20030092901
    Abstract: The present invention relates to an improved method for forming a protein-oligonucleotide conjugate. The method is particularly amenable for forming antibody-oligonucleotide conjugates. The invention further concerns the conjugate molecules produced using such improved methods.
    Type: Application
    Filed: October 24, 2001
    Publication date: May 15, 2003
    Inventors: Firdous Farooqui, Parameswara Meda Reddy
  • Methods and reagents for improved cell-based assays
    Publication number: 20030077569
    Abstract: The ability to efficiently determine the state of enzyme expression in cells has long been desired as material to the diagnosis of disease. This invention relates to cytoenzymology, and more particularly to improved reagents for use in cell-based assays, especially those using fluorogenic substrates.
    Type: Application
    Filed: October 15, 2001
    Publication date: April 24, 2003
    Inventors: Adrian Clausell, Jirong Gu, Parameswara Meda Reddy