Abstract: This disclosure relates to DNA aptamers that bind eosinophil peroxidase, including uses thereof, such as in eosinophil peroxidase detection assays. Also provided is a method for detecting the presence of eosinophil peroxidase in a sample, using the DNA aptamers that bind eosinophil peroxidase. Further provided is a kit for detecting the presence of eosinophil peroxidase in a sample, using the DNA aptamers that bind eosinophil peroxidase.

Abstract: A formulation of pure dimethoxy curcumin-human serum albumin (DMCHSA) comprising a pure di-methoxy curcumin (DMC) bound to human serum albumin (HSA), wherein molar ratio of DMC to HSA is in the range of 3.0-6.0. Further, there is provided a highly soluble and safe intravenous formulation of pure dimethoxy curcumin-human serum albumin retaining proven biological activities and a process for the preparation thereof. Even further, there is provided a process for preparing formulation of pure dimethoxy curcumin-human serum albumin (DMCHSA) by preferential binding of DMC to HSA, which excludes other curcuminoids such as Demethoxy curcumin (DeMC) and Bidemethoxy curcumin (BiDeMC) present in the added chemical, increasing the purity of 80% DMC in starting raw material to >99% in the product DMCHSA.

Abstract: Techniques are disclosed for security management during an onboarding process for user equipment. For example, from a perspective of an onboarding network, a method comprises authenticating, via the onboarding network, user equipment based on an onboarding record previously configured for the user equipment or a set of user equipment and maintained by the onboarding network. Upon successful authentication, a communication session is established from the onboarding network to a provisioning server for remote provisioning of the user equipment. Advantageously, the onboarding process is performed without a default credential server.

Abstract: Disclosed herein are methods of treating severe glucocorticoid-dependent eosinophilic asthma in a subject whose asthma has been inadequately controlled with subcutaneously-administered mepolizumab. Also provided are methods of predicting responsiveness to anti-IL-5 antibody treatment in a subject having severe glucocorticoid-dependent eosinophilic asthma.

Abstract: Various communication systems may benefit from improved radio access network paging procedures. For example, it may be helpful to enhance radio access network paging procedures for a user equipment in a radio resource control inactive mode. According to certain embodiments a method may include receiving a setup request at a network entity. The setup request may comprise a supported radio access network based notification area for a user equipment movement in a radio resource control inactive mode. The method may also include transmitting a radio access network paging message from the network entity to a neighboring network entity supporting a configured network slice within the supported radio access network based notification area. The method may further include paging for the user equipment in a radio resource control inactive mode in cells included in the radio access network based notification area that support the configured network slice for the user equipment.

Abstract: Disclosed herein are methods of treating severe glucocorticoid-dependent eosinophilic asthma in a subject whose asthma has been inadequately controlled with subcutaneously-administered mepolizumab. Also provided are methods of predicting responsiveness to anti-IL-5 antibody treatment in a subject having severe glucocorticoid-dependent eosinophilic asthma.

Abstract: An intelligent LAN modem node is used in a bridge system which provides transparent internetwork communications over a plurality of channels. The LAN modem node is protocol independent and has a packet load distribution system which shares packet traffic across the channels using optional user-defined channel preferences. The LAN modem nodes used in the bridge system provides compression for increasing bridge transmission speed. The bridge system provides a filtering system to control access over the bridge and restrict unnecessary bridge traffic. Additionally, the bridge system provides automatic redial in the event modem communications are lost.

Abstract: A proxy server shares a plurality of modems connected to a wide area network among multiple client computers connected to a local area network. Each of the client computers on the local area network is assigned a local address while each of the plurality of modems is assigned a modem port address valid on the wide area network. In one embodiment, a processor controls address substitution allowing multiple client computers to share modems when communicating to host computers in a wide area network. The processor creates a descriptor list to keep track of the connections between the client computer and host computers on the wide area network and uses the descriptor list to determine to which client computer an incoming data packet should be sent. The processor also creates a proxied application list to determine if an outgoing data packet, received from one of the client computers, is one to be proxied through the proxy server.