Patents by Inventor Pardis ASSI

Pardis ASSI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THE ATR KINASE INHIBITOR BAY1895344 FOR USE IN THE TREATMENT OF A HYPER-PROLIFERATIVE DISEASE
    Publication number: 20220117973
    Abstract: The present invention relates to the ATR kinase inhibitor, 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine, for use in the treatment of a hyper-proliferative disease, characterized in that it is administered in an amount of from 10 mg to 160 mg per day, particularly in an amount of 60 to 160 mg per day. The present invention also relates to a pharmaceutical composition comprising 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine in an amount of from 5 mg to 80 mg and at least one pharmaceutically acceptable excipient. The present invention also relates to a process for manufacturing said pharmaceutical composition.
    Type: Application
    Filed: February 6, 2020
    Publication date: April 21, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Dennis KRICKAU, Eleni LAGKADINOU, Antje Margret WENGNER, Michael KRAUSE, Peter SERNO, Michaela BAIRLEIN, Gary WILKINSON, Siobhan WATTERS, Pardis ASSI