Abstract: Aqueous coating compositions are disclosed that are capable of forming residual antimicrobial coatings having improved performance related to residual efficacy and duration. In various embodiments, an antimicrobial coating composition comprises at least one antimicrobial compound, at least one durable matrix forming compound, and optionally, at least one performance-enhancing additive. The antimicrobial compound is selected from non-silane quaternary compounds and quaternary silanes. The durable matrix forming compound is selected from polymers, non-polymeric organic compounds, inorganic substances, additional antimicrobial substances, reactive silanes, and non-reactive silanes. The performance-enhancing additive is selected from a polymer, a solvent, an inorganic substance, a surfactant, a crosslinker, a surface modifier, and chemical species capable of forming a sol-gel.

Abstract: Systems, indicator wipe product, and methods thereof used to detect the presence of cationic polymer residues on a surface are described. In various embodiments, the cationic polymer to be detected comprises a quaternary silane residual antimicrobial. The indicator wipe may comprise a woven, nonwoven, or double-knit fabric, cotton, functional cellulose, or open cell foam material substrate impregnated with an aqueous dye solution comprising a sulfonephthalein dye. The indicator wipe may be configured to differentiate between traditional monomer quaternary ammonium compounds and cationic polymers such as quaternary silane compounds used in residual antimicrobial coatings by color changes on the indicator wipe and by observing if cationic-dye complexes diffuse by chromatography on the indicator wipe.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.