Abstract: The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.

Abstract: The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.

Abstract: A wireless powering system for an implantable medical device includes a first unit having a power source and an inductive coil. A second unit has an energy storage component and in alternate embodiments one or two inductive coils. The implantable medical device includes an inductive coil and a functional load. A method of wirelessly powering an implantable medical device is also included. The embodiments provide a method for wireless powering of an implantable medical device. Through the use of a three tiered inductive power system, power can be wirelessly transmitted from near the skin of the patient to the location of the implant. The implant can be reduced in size and can have a longer lifespan due to the elimination of an integrated battery. The versatility of the implant can allow for improved and more secure fixation to the tissue of interest.