Patents by Inventor Paritosh Jayant Dhawale
Paritosh Jayant Dhawale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11110185Abstract: The present invention relates to in vivo imaging and in particular to magnetic resonance imaging (MRI). Provided by the present invention is a pharmaceutical formulation suitable for use in an MRI procedure and which offers advantages over known such formulations. A particular dose of the pharmaceutical formulation of the invention is also envisioned as well as the use of said dose in a method of in vivo imaging. This present invention provides for simultaneous administration of a liver specific agent and a second MR contrast agent that is capable of better/further enhancing the dynamic vascular phase in a patient. The method of the invention has the advantage of simplicity and patient comfort, compared to sequential injections. Furthermore, the method of the invention provides the advantage that it can enable a lower cumulative dose of contrast agents.Type: GrantFiled: November 30, 2016Date of Patent: September 7, 2021Assignee: GE HEALTHCARE ASInventors: Andreas Richard Meijer, Mikkel Jacob Thaning, Paritosh Jayant Dhawale, Salvatore Desena, Paul Alexander Jones, Deirdre Cassidy, Concetta Valeria Gringeri
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Publication number: 20180303960Abstract: The present invention relates to in vivo imaging and in particular to magnetic resonance imaging (MRI). Provided by the present invention is a pharmaceutical formulation suitable for use in an MRI procedure and which offers advantages over known such formulations. A particular dose of the pharmaceutical formulation of the invention is also envisioned as well as the use of said dose in a method of in vivo imaging. This present invention provides for simultaneous administration of a liver specific agent and a second MR contrast agent that is capable of better/further enhancing the dynamic vascular phase in a patient. The method of the invention has the advantage of simplicity and patient comfort, compared to sequential injections. Furthermore, the method of the invention provides the advantage that it can enable a lower cumulative dose of contrast agents.Type: ApplicationFiled: November 30, 2016Publication date: October 25, 2018Applicant: GE Healthcare ASInventors: Andreas Richard Meijer, Mikkel Jacob Thaning, Paritosh Jayant Dhawale, Salvatore Desena, Paul Alexander Jones, Deirdre Cassidy, Concetta Valeria Gringeri
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Patent number: 9627097Abstract: Systems, apparatus and methods are provided through which an injector system automates a process of injecting an individual dose from a multiple dose of a radiotracer material. In some embodiments, the injector system includes a first dose calibrator system that receives a multidose vial of a radiotracer, a second dose calibrator system, an injection pump and an intravenous needle. In some embodiments, the first dose calibrator system and the multidose vial have an integrated shape. In some embodiments, the first dose calibrator system includes a pneumatic arm that receives the multidose vial.Type: GrantFiled: March 2, 2004Date of Patent: April 18, 2017Assignee: General Electric CompanyInventors: Mark Alan Jackson, Paritosh Jayant Dhawale, Hernan Rodrigo Lara, Michael Brussermann, Ulrich Ketzscher
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Publication number: 20100286512Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.Type: ApplicationFiled: May 17, 2010Publication date: November 11, 2010Applicant: GENERAL ELECTRIC COMPANYInventors: Paritosh Jayant Dhawale, Mark Alan Jackson, Hernan Rodrigo Lara, Michael Brussermann, Ulrich Ketzscher
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Patent number: 7734331Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.Type: GrantFiled: March 2, 2004Date of Patent: June 8, 2010Assignee: General Electric CompanyInventors: Paritosh Jayant Dhawale, Mark Alan Jackson, Hernan Rodrigo Lara, Michael Brussermann, Ulrich Ketzscher
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Publication number: 20100121184Abstract: In one aspect, systems, methods and apparatus are provided through which a dispensing station dispenses a large quantity of a radiotracer to one or more positron emission tomography imaging stations. In some aspects a quality control unit verifies the quality of the radiotracer. In some embodiments, components of the system are coupled by a local area network. In some aspects, each positron emission tomography imaging station includes an injector system, a physiological monitoring device, and a positron emission tomography scanner. All of the devices can be controlled by a computer system.Type: ApplicationFiled: March 2, 2004Publication date: May 13, 2010Applicant: General Electric CompanyInventors: Paritosh Jayant Dhawale, Mark Alan Jackson, Hernan Rodrigo Lara, Michael Brussermann, Ulrich Ketzscher
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Publication number: 20080242915Abstract: Systems, apparatus and methods are provided through which an injector system automates a process of injecting an individual dose from a multiple dose of a radiotracer material. In some embodiments, the injector system includes a first dose calibrator system that receives a multidose vial of a radiotracer, a second dose calibrator system, an injection pump and an intravenous needle. In some embodiments, the first dose calibrator system and the multidose vial have an integrated shape. In some embodiments, the first dose calibrator system includes a pneumatic arm that receives the multidose vial.Type: ApplicationFiled: March 2, 2004Publication date: October 2, 2008Applicant: General Electric CompanyInventors: Mark Alan Jackson, Paritosh Jayant Dhawale, Hernan Rodrigo Lara, Michael Brussermann, Ulrich Ketzscher
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Patent number: 6879660Abstract: A technique is provided in which a gain correction map derived for a detector at one X-ray spectrum may be adapted to accommodate images acquired by the detector at a different X-ray spectrum. The technique accounts for the physical variations in the detector which may produce spectrally-sensitive artifacts as well as for the particular image acquisition conditions. A technique is also provided for correcting edge artifacts in an acquired image by measuring median signal intensity within columns or rows of the image and deriving correction factors for the respective edge columns or rows based upon the trends of the median signal intensities. A technique is also provided for storing detector attributes during a manufacturing calibration process and accessing them during system operation such that a suitable gain correction factor is employed based upon the spectrum and operating conditions.Type: GrantFiled: December 18, 2002Date of Patent: April 12, 2005Assignee: General Electric CompanyInventors: Paritosh Jayant Dhawale, Douglas Albagli
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Publication number: 20040265235Abstract: Magnetic resonance (“MR”) contrast-enhancing agents comprise poly(amino acid) backbone chain conjugated to chelating moieties that comprise a plurality of carboxylic acid groups that form coordination complexes with paramagnetic ions. A method for detecting atherosclerotic plaque areas comprises administering at least one of these contrast agents into a subject; and obtaining and comparing MR images of and MR signals from the plaque areas before and after administering the contrast agent. The method can be used to assess an effectiveness of a prescribed course of treatment for atherosclerosis.Type: ApplicationFiled: June 26, 2003Publication date: December 30, 2004Inventors: Egidijus Edward Uzgiris, Mohan Mark Amaratunga, William Thomas Dixon, Paritosh Jayant Dhawale, Ahmad Nadeem Ishague
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Publication number: 20040120468Abstract: A technique is provided for reducing or eliminating spectrally-sensitive artifacts in an X-ray image. In particular, a technique is provided in which a gain correction map derived for a detector at one X-ray spectrum may be adapted to accommodate images acquired by the detector at a different X-ray spectrum. The technique accounts for the physical variations in the detector which may produce spectrally-sensitive artifacts as well as for the particular image acquisition conditions. A technique is also provided for correcting edge artifacts in an acquired image by measuring median signal intensity within columns or rows of the image and deriving correction factors for the respective edge columns or rows based upon the trends of the median signal intensities. A technique is also provided for storing detector attributes during a manufacturing calibration process and accessing them during system operation such that a suitable gain correction factor is employed based upon the spectrum and operating conditions.Type: ApplicationFiled: December 18, 2002Publication date: June 24, 2004Inventors: Paritosh Jayant Dhawale, Douglas Albagli
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Publication number: 20040102691Abstract: A method and system for correcting examination images acquired by a magnetic resonance imaging (MRI) device are provided. The method comprises the steps of imaging a phantom of known structure at selected intervals to generate phantom images, analyzing the phantom images relative to images of the phantom acquired at a previous time, calculating variations between respective phantom images, and correcting the examination images and/or measurements based off the examination images using the calculated variations between phantom images. The system comprises an imaging device for acquiring images of a subject and the phantom and an image processor adapted to correct the examination images based on the calculated variations between respective phantom images.Type: ApplicationFiled: November 25, 2002Publication date: May 27, 2004Applicant: General Electric CompanyInventors: Richard Philip Mallozzi, Ricardo Scott Avila, Paritosh Jayant Dhawale, Daniel James Blezek
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Patent number: 6314160Abstract: The present invention provides an adaptive fluoroscopic noise reduction (FNR) algorithm utilizing various data acquisition parameters to generate an estimation of the noise statistics and to predict a minimal object contrast associated with the object. The estimation of the noise statistics and the prediction of the object contrast are then utilized to adapt certain variables that are utilized by the FNR algorithm. The estimation of noise statistics and the prediction of object contrast may be adapted on a pixel-by-pixel basis by using a regional mean to obtain an adapted estimation of noise statistics and an adapted prediction of object absolute contrast. The variables of the FNR algorithm are then adapted based on the adapted noise statistics estimation and the adapted prediction of object absolute contrast.Type: GrantFiled: December 17, 1999Date of Patent: November 6, 2001Assignee: General Electric CompanyInventors: Paritosh Jayant Dhawale, Thierry Lebihen, Gregory Michael Kautz