Patents by Inventor Parkson Lee-Gau Chong

Parkson Lee-Gau Chong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for screening/ranking antioxidants based on their effects on membrane sterol lateral organization
    Patent number: 8183048
    Abstract: A method of screening an antioxidant for potency and/or toxicity in vitro, the method includes contacting the antioxidant with a model system containing a sterol superlattice formation capable of generating a detectable signal, wherein the detectable signal changes in a parameter representative of an integrity of the sterol superlattice formation; and detecting and/or measuring disruption of the sterol superlattice formation, wherein the disruption is caused by the insertion of the antioxidant into membranes and thereby screening the antioxidant for potency and/or toxicity.
    Type: Grant
    Filed: July 25, 2008
    Date of Patent: May 22, 2012
    Assignee: Temple University- Of the Commonwealth System of Higher Education
    Inventors: Parkson Lee-Gau Chong, Michelle Olsher, Su-In Yoon
  • AN ASSAY FOR SCREENING/RANKING ANTIOXIDANTS BASED ON THEIR EFFECTS ON MEMBRANE STEROL LATERAL ORGANIZATION
    Publication number: 20100291687
    Abstract: A method of screening an antioxidant for potency and/or toxicity in vitro, the method includes contacting the antioxidant with a model system comprising a sterol superlattice formation capable of generating a detectable signal, wherein the detectable signal changes in a parameter representative of an integrity of the sterol superlattice formation; and detecting and/or measuring disruption of the sterol superlattice formation, wherein the disruption is caused by oxidation of sterol upon contacting sterol with a prooxidant and the antioxidant and thereby screening the antioxidant for potency and/or toxicity.
    Type: Application
    Filed: July 25, 2008
    Publication date: November 18, 2010
    Applicant: TEMPLE UNIVERSITY- OF THE COMMONWEATH SYSTEM OF HIGHER EDUCATION
    Inventors: Parkson Lee-Gau CHONG, Michelle OLSHER, Su-In YOON