Patents by Inventor Parmeswaran Diagaradjane

Parmeswaran Diagaradjane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatments of disease or disorders using nanoparticles for focused hyperthermia to increase therapy efficacy
    Patent number: 9211419
    Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: December 15, 2015
    Assignees: Nanospectra Biosciences, Inc., Board of Regents, The University of Texas System
    Inventors: Sunil Krishnan, Parmeswaran Diagaradjane, Jon Alexander Schwartz, James Chunjay Wang
  • ENHANCEMENT OF RADIATION THERAPY BY TARGETED HIGH-Z NANOPARTICLES
    Publication number: 20130225901
    Abstract: A method for the design, manufacturing, and use of a high-Z particle to enhance the effects of ionizing radiation. In particular, the use of a targeting molecule to enable cellular uptake by the target cells (tumor cells or endothelial cells proximate to the tumor) will enhance the dose effect.
    Type: Application
    Filed: April 5, 2011
    Publication date: August 29, 2013
    Applicant: NANOSPECTRA BIOSCIENCES, INC.
    Inventors: Sunil Krishnan, Parmeswaran Diagaradjane, Glenn P. Goodrich, J. Donald Payne
  • TREATMENTS OF DISEASE OR DISORDERS USING NANOPARTICLES FOR FOCUSED HYPERTHERMIA TO INCREASE THERAPY EFFICACY
    Publication number: 20130197295
    Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.
    Type: Application
    Filed: January 16, 2013
    Publication date: August 1, 2013
    Applicants: The Board of Regents of the University of Texas System, Nanospectra Biosciences, Inc.
    Inventors: Sunil Krishnan, Parmeswaran Diagaradjane, Jon Alexander Schwartz, James Chunjay Wang
  • TREATMENTS OF DISEASE OR DISORDERS USING NANOPARTICLES FOR FOCUSED HYPERTHERMIA TO INCREASE THERAPY EFFICACY
    Publication number: 20110052672
    Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.
    Type: Application
    Filed: January 16, 2009
    Publication date: March 3, 2011
    Inventors: Sunil Krishnan, Parmeswaran Diagaradjane, Jon Alexander Schwartz, James Chunjay Wang