Patents by Inventor Parmjit Singh Jat

Parmjit Singh Jat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mice expressing TSSV40 large T antigen
    Patent number: 5866759
    Abstract: The provision of cell lines from virtually any cell type of the animal body is greatly facilitated by transgenic non-human eukaryotic animals of the invention in which at least some cells have (i) a differentiation inhibiting sequence chromosomally incorporated under the control of a non-constitutive promotor and/or (ii) a differentiation inhibiting sequence which is itself conditionally active. Said genes are chromosomally incorporated under the control of a promotor such that expression of said sequence is normally held below an effective level, thus allowing normal cell development. However, cells taken from said animal may be prevented from completing differentiation to a non-dividing state in tissue culture by activating expression of said sequence.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: February 2, 1999
    Assignee: Ludwig Institute For Cancer Research
    Inventors: Parmjit Singh Jat, Dimitris Kioussis, Mark David Noble
  • Transgenic mouse cells expressing ts SV40 large T
    Patent number: 5688692
    Abstract: The provision of cell lines from virtually any cell type of the animal body is greatly facilitated by transgenic non-human eukaryotic animals of the invention in which at least some cells have (i) a differentiation inhibiting sequence chromosomally incorporated under the control of a non-constitutive promotor and/or (ii) a differentiation inhibiting sequence which is itself conditionally active. Said genes are chromosomally incorporated under the control of a promotor such that expression of said sequence is normally held below an effective level, thus allowing normal cell development. However, cells taken from said animal may be prevented from completing differentiation to a non-dividing state in tissue culture by activating expression of said sequence.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: November 18, 1997
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Parmjit Singh Jat, Dimitris Kioussis, Mark David Noble