Patents by Inventor Parthasarathi Rajagopalan

Parthasarathi Rajagopalan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives
    Patent number: 5043350
    Abstract: Benzo-fused cycloalkane and oxa- and thia- cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetra hydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: August 27, 1991
    Assignee: Du Pont Merck Pharmaceutical Company
    Inventors: Penio Pennev, Parthasarathi Rajagopalan, Richard M. Scribner
  • Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine derivatives
    Patent number: 5010085
    Abstract: Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetrahy dronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: April 23, 1991
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Penio Pennev, Parthasarathi Rajagopalan, Richard M. Scribner
  • Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives
    Patent number: 4929627
    Abstract: Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetra hydronaphth-1-yl]benezeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics and/or diuretics.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: May 29, 1990
    Assignee: E. I. Du Pont De Nemours and Company
    Inventors: Penio Pennev, Parthasarathi Rajagopalan, Richard M. Scribner
  • Benoz-fused cycloalkane trans-1,2-diamine derivatives
    Patent number: 4876269
    Abstract: Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetra hydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts of N-oxides thereof, are useful as analgesics and/or diuretics.
    Type: Grant
    Filed: July 16, 1987
    Date of Patent: October 24, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Penio Pennev, Parthasarathi Rajagopalan, Richard M. Scribner
  • Pyridoindolobenzodiazepine tranquilizers
    Patent number: 4438120
    Abstract: Pyridoindolobenzodiazepines, including 1,2,3,4-tetrahydropyrido[4',3':2,3]indolo[1,7-ab][1,4]benzodiazepine-9(8H) -ones and 1,2,3,4,8,9-hexahydro- and 1,2,3,4,4a,8,9,14a-octahydropyrido[4',3':2,3]indolo[1,7-ab][1,4]benzodiaze pines, are useful as tranquilizers.
    Type: Grant
    Filed: November 12, 1982
    Date of Patent: March 20, 1984
    Assignee: E. I. Du Pont de Nemours & Company
    Inventor: Parthasarathi Rajagopalan
  • 1,2,3,4,4a,5,10,10a-Octahydro-5,10-ortho-benzenobenz[g]isoquinolines and antidepressant use thereof
    Patent number: 4351836
    Abstract: This invention relates to (.+-.)1,2,3,4,4a,5,10,10a-octahydro-5,10-o-benzenobenz[g]isoquinoline derivatives which are useful as antidepressants.
    Type: Grant
    Filed: July 28, 1980
    Date of Patent: September 28, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Parthasarathi Rajagopalan
  • Cis- and trans- octahydropyridopyrrolobenzheterocycles
    Patent number: 4219550
    Abstract: cis- and trans- Octahydropyridopyrrolobenzheterocycles of the formula: ##STR1## where ##STR2## X=O or S; R.sub.1 =H, C.sub.1 -C.sub.4 straight or branched chain alkyl or cyclopropyl; and R.sub.2 =H, CH.sub.3, OCH.sub.3, Cl, Br, F or CF.sub.3.The compounds are useful as tranquilizers and antidepressants.
    Type: Grant
    Filed: November 9, 1978
    Date of Patent: August 26, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Parthasarathi Rajagopalan
  • Pyridopyrrolobenzheterocycles
    Patent number: 4183936
    Abstract: The compounds are prepared by cyclizing compounds of formula II ##STR2## wherein R.sup.2 is R.sup.1 or acyl.
    Type: Grant
    Filed: June 16, 1978
    Date of Patent: January 15, 1980
    Assignee: Endo Laboratories, Inc.
    Inventor: Parthasarathi Rajagopalan
  • Pyridopyrrolobenzheterocycles
    Patent number: 4115577
    Abstract: The compounds are prepared by cyclizing compounds of formula II ##STR2## wherein R.sup.2 is R.sup.1 or acyl.
    Type: Grant
    Filed: December 28, 1976
    Date of Patent: September 19, 1978
    Assignee: Endo Laboratories, Inc.
    Inventor: Parthasarathi Rajagopalan
  • Tris[tetrahydroisoquinoline] compounds
    Patent number: 4107165
    Abstract: Novel alkylenetris- and alkylenetetrakis-[1,2,3,4-tetrahydroisoquinoline] and -[3,4-dihydroisoquinoline] compounds, the pharmaceutically acceptable acid addition salts thereof and compositions containing such substances have been found useful for inhibiting the formation of blood clots in mammals and/or dissolving blood clots in mammals after they have been formed.
    Type: Grant
    Filed: September 15, 1976
    Date of Patent: August 15, 1978
    Assignee: Endo Laboratories
    Inventors: Parthasarathi Rajagopalan, Irwin J. Pachter
  • Pyridopyrrolobenzoxazine
    Patent number: 4013652
    Abstract: Compounds of the formula: ##STR1## where 2 THE R's are the same or different and are H or CH.sub.3, and one of them can be C.sub.2 -C.sub.9 alkyl or phenyl; R.sup.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.2l -C.sub.4 alkoxycarbonyl, or substituted C.sub.1 -C.sub.4 alkyl where the substituent is C.sub.3 -C.sub.6 cycloalkyl or phenyl; and Z is H, Cl or CH.sub.3 ; and their pharmaceutically suitable salts. The compounds are useful as sedatives; some of them also exhibit antidepressant activity.
    Type: Grant
    Filed: June 13, 1975
    Date of Patent: March 22, 1977
    Assignee: Endo Laboratories, Inc.
    Inventor: Parthasarathi Rajagopalan