Patents by Inventor Parul Angrish

Parul Angrish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11697841
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: July 11, 2023
    Assignee: Life Technologies Corporation
    Inventors: Parul Angrish, Zhiwei Yang, Jonathan Wang
  • Publication number: 20230212662
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Application
    Filed: December 22, 2022
    Publication date: July 6, 2023
    Inventors: Parul ANGRISH, Zhiwei YANG, Jonathan WANG
  • Publication number: 20230181742
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Application
    Filed: August 19, 2022
    Publication date: June 15, 2023
    Inventors: Zhiwei Yang, Parul Angrish, Xavier de Mollerat Du Jeu, Kristin Wiederholt
  • Publication number: 20230100065
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Application
    Filed: October 6, 2022
    Publication date: March 30, 2023
    Inventors: Parul Angrish, Zhiwei Yang
  • Patent number: 11479814
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: October 25, 2022
    Inventors: Parul Angrish, Zhiwei Yang
  • Patent number: 11464863
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: October 11, 2022
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Zhiwei Yang, Parul Angrish, Xavier de Mollerat du Jeu, Kristin Wiederholt
  • Publication number: 20200340048
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Application
    Filed: May 8, 2020
    Publication date: October 29, 2020
    Inventors: Parul ANGRISH, Zhiwei YANG, Jonathan WANG
  • Publication number: 20200332343
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Application
    Filed: May 4, 2020
    Publication date: October 22, 2020
    Inventors: Parul ANGRISH, Zhiwei YANG
  • Patent number: 10683539
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: June 16, 2020
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Parul Angrish, Zhiwei Yang
  • Patent number: 10676785
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: June 9, 2020
    Assignee: Life Technologies Corporation
    Inventors: Parul Angrish, Zhiwei Yang, Jonathan Wang
  • Publication number: 20200061197
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Application
    Filed: August 30, 2019
    Publication date: February 27, 2020
    Inventors: Zhiwei YANG, Parul ANGRISH, Xavier de MOLLERAT du JEU, Kristin WIEDERHOLT
  • Patent number: 10406237
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: September 10, 2019
    Assignee: LIFE TECHNOLOLGIES CORPORATION
    Inventors: Zhiwei Yang, Parul Angrish, Xavier de Mollerat du Jeu, Kristin Wiederholt
  • Publication number: 20190119739
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Application
    Filed: December 19, 2018
    Publication date: April 25, 2019
    Inventors: Parul ANGRISH, Zhiwei YANG, Jonathan WANG
  • Patent number: 10202639
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: February 12, 2019
    Assignee: Life Technologies Corporation
    Inventors: Parul Angrish, Zhiwei Yang, Jonathan Wang
  • Publication number: 20180223334
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Application
    Filed: January 29, 2018
    Publication date: August 9, 2018
    Inventors: Parul ANGRISH, Zhiwei YANG
  • Publication number: 20180200374
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Application
    Filed: December 15, 2017
    Publication date: July 19, 2018
    Inventors: Zhiwei YANG, Parul ANGRISH, Xavier de MOLLERAT du JEU, Kristin WIEDERHOLT
  • Patent number: 9914964
    Abstract: This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in nucleic acid synthesis or amplification reactions such as a polymerase chain reaction (PCR). Methods for preparing the novel compounds are also described.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: March 13, 2018
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Parul Angrish, Zhiwei Yang
  • Patent number: 9901642
    Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: February 27, 2018
    Assignee: Life Technologies Corporation
    Inventors: Zhiwei Yang, Parul Angrish, Xavier de Mollerat du Jeu, Kristin Wiederholt, Tao Wu
  • Publication number: 20170073746
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 16, 2017
    Inventors: Parul ANGRISH, Zhiwei YANG, Jonathan WANG
  • Patent number: 9493414
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: November 15, 2016
    Assignee: Life Technologies Corporation
    Inventors: Parul Angrish, Zhiwei Yang, Jonathan Wang