Patents by Inventor Parvathi RANGANATHAN

Parvathi RANGANATHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MIR155 AS THE INTEGRATION SITE TO OVERCOME ACUTE GRAFT VERSUS HOST DISEASE OF GENE-MODIFIED IMMUNE EFFECTOR CELLS
    Publication number: 20250032545
    Abstract: The present disclosure relates to CAR-T cells and uses thereof. Disclosed herein is a genetically modified T cell comprising a nucleic acid sequence encoding a chimeric antigen receptor (CAR) polypeptide comprising a single-chain variable fragment (scFV) that specifically binds to a target molecule, wherein the nucleic acid sequence encoding the CAR polypeptide is integrated into an integration site located at a miR-155 host gene.
    Type: Application
    Filed: July 26, 2024
    Publication date: January 30, 2025
    Inventors: Parvathi Ranganathan, Meisam Naeimi Kararoudi, Yasemin Sezgin, Dean Lee
  • GENETICALLY MODIFIED CELLS AND USES THEREOF FOR PREVENTION OF ACUTE GRAFT-VERSUS-HOST DISEASE
    Publication number: 20240124840
    Abstract: The present disclosure relates to compositions and methods for preventing and treating acute graft-versus-host disease.
    Type: Application
    Filed: February 22, 2022
    Publication date: April 18, 2024
    Inventors: Parvathi RANGANATHAN, Ramiro GARZON