Patents by Inventor Parven Kumar Luthra

Parven Kumar Luthra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of cephalosporins
    Publication number: 20040132995
    Abstract: The present invention relates to a process for the preparation of cephalosporin antibiotics of the formula (I) 1
    Type: Application
    Filed: November 5, 2003
    Publication date: July 8, 2004
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS, LTD.
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra, Ramakrishna Kamma, Gedi Sreedhar
  • Process for the preparation of cefditoren using the thioester of thiazolylacetic acid
    Patent number: 6713625
    Abstract: The present invention provides a process for the preparation of Cefditoren of the formula (I) which comprises acylating 7-amino-cephem carboxylic acids of the general formula (IV) where R3 is hydrogen or trimethylsilyl with thioester derivatives of the formula (II) wherein R1 represents C1-C4 alkyl or phenyl in an organic solvent in the presence of an organic base at a temperature in the range of −10° C. to 30° C.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: March 30, 2004
    Assignee: Orchid Chemicals & Pharmaceuticals Ltd.
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra
  • Process for the preparation of cefditoren using the thioester of thiazolylacetic acid
    Publication number: 20030225265
    Abstract: The present invention provides a process for the preparation of Cefditoren of formula (I) 1
    Type: Application
    Filed: May 23, 2002
    Publication date: December 4, 2003
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra
  • Process for the preparation of thiazole intermediate
    Publication number: 20030204095
    Abstract: The present invention provides a process for the preparation of 4-methyl-5-formyl-thiazole of the formula (I) 1
    Type: Application
    Filed: December 5, 2002
    Publication date: October 30, 2003
    Applicant: Orchid Chemicals & Pharmaceuticals Limited
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra, Rajesh Vyas, Ramakrishna Kamma
  • Process for the preparation of cephalosporin intermediate and its use for the manufacture of cephalosporin compounds
    Publication number: 20030199712
    Abstract: The present invention relates to a process for the preparation of 4-halogeno-2-substitutedimino-3-oxo-butyric acid of formula (I) 1
    Type: Application
    Filed: September 18, 2002
    Publication date: October 23, 2003
    Applicant: Orchid Chemicals and Pharmaceuticals Limited
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra, Pratik Ramesh Sathe, Sivakumaran Sundaravadivelan, Praveen Nagesh Ganesh
  • Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
    Patent number: 6610845
    Abstract: The present invention provides new thioester derivatives of thiazolyl acetic acid of the general formula (I), wherein, R1 represents H, trityl, CH3, CRaRbCOOR2 (Ra and Rb independently of one another represents hydrogen or methyl and R2 represents H or C1-C4 alkyl). also, the invention provides a method by which the said thioester derivatives can be prepared by reacting thiazolyl acetic acid of the general formula (IV) with 1,2,5,6 tetrahdro-2-methyl-5,6 dioxo-1,2,4-triazin-3-thiol of the formula (VI) in a solvent, in presence of an organic base and with the help of Vilsmeier reagent of the formula (V). The so obtained thioester derivatives are reacted with 7-amino-cephem carboxylic acids of the general formula (III) to produce cephalosporin antibiotic compounds having the general formula (II).
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: August 26, 2003
    Assignee: Orchid Chemicals & Pharmaceuticals Limited, India
    Inventors: Pandurang Balwant Deshpande, Pramod Narayan Deshpande, Shanmugam Srinivasan, Parven Kumar Luthra, Gautam Kumar Das
  • Method for the preparation of ceftiofur sodium
    Patent number: 6555680
    Abstract: The present invention relates to a process for the preparation of sodium salt of Ceftiofur as given in Formula I, directly from its amine salt using sodium base.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: April 29, 2003
    Assignee: Orchid Chemicals & Pharmaceuticals Ltd.
    Inventors: Pandurang Balwant Deshpande, Pramod Narayan Deshpande, Milind Ramkrishna Kulkarni, Parven Kumar Luthra
  • Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
    Patent number: 6388070
    Abstract: The present invention provides novel thioester derivatives of thiazolyl acetic acid of the general formula (I), wherein, R1 represents H, trityl, CH3, or CRaRbCOOR3, in which Ra and Rb, independently of one another, represents hydrogen or methyl and R3 represents H or C1-C7 alkyl; and R2 represents C1-C4 alkyl or phenyl.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: May 14, 2002
    Assignee: Orchid Chemicals & Pharmaceuticals Ltd.
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra
  • Preparation of new intermediates and their use in manufacturing of cephalosporin compounds
    Patent number: 6384215
    Abstract: The present invention provides new thioester derivatives of 4-halogeno-2-methoxyimino-3-oxo-butyric acid of the general formula (I), also, the invention provides a method by which the said thioester derivatives can be prepared by reacting 4-halogeno-2-methoxyimino-3-oxo-butyric acid of the general formula (II) with 2-mercapto-5-substituted-1,3,4-oxadiazoles of the general formula (III) in a solvent, in the presence of DMF/POCl3 and in presence of an organic base and if desired the so obtained thioester derivatives so obtained are reacted with 7-amino-cephem carboxylic acids of the general formula (V) to produce condensed products which are insitu reacted with thiourea to get cephalosporin antibiotic compounds having the general formula (VI).
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: May 7, 2002
    Assignee: Orchid Chemicals & Pharmaceuticals Ltd.
    Inventors: Pandurang Balwant Deshpande, Parven Kumar Luthra