Abstract: In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes.

Abstract: In various embodiments novel allosteric antagonists of the CRFR1 receptor are provided. It discovered that allosteric CRFR1 receptor antagonists are effective to modulate p-Tau levels in Alzheimer's disease (AD) models. In one illustrative embodiment, a compound that is a CRFR1 receptor antagonist is a compound according to the formula or a pharmaceutically acceptable salt, ester, amide, solvate, or prodrug thereof.

Abstract: There are provided, inter alia, compounds and methods useful for the treatment of neurological conditions, such as neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

Abstract: In various embodiments deformable nano-scale vehicles (DNV) are provided that are useful for the delivery of therapeutic agents. In certain embodiments the DNVs are capable of transdermal delivery and can additionally cross the blood-brain barrier.

Abstract: In various embodiments novel allosteric antagonists of the CRFR1 receptor are provided. It discovered that allosteric CRFR1 receptor antagonists are effective to modulate p-Tau levels in Alzheimer's disease (AD) models.

Abstract: There are provided, inter alia, compounds and methods useful for the treatment of neurological conditions, such as neurological disorders and neurodegenerative diseases, including Alzheimer's Disease.

Abstract: A novel pt/pd sodalite caged catalyst combination with sulfided base metal catalyst for improved catalytic hydroprocessing of renewable feedstock. Particularly, the invention relates to a process for preparation of the said catalyst. More particularly, the invention relates to a process for the preparation of hydrocarbon fuel from the feed stock using a said catalyst. Further, the invention discloses a novel catalyst and a process for the preparation of the Pt/Pd encapsulated in sodalite cage with silica-alumina ZSM-5 synthesized around it supported with nickel, molybdenum, cobalt, tungsten or one or more thereof. The invention also provides process to convert vegetable oils, free fatty acids, and microbial lipids, bio-crude and conventional non-renewable crude based feed stocks such as diesel, naphtha, kerosene, gas oil, residue, etc.

Abstract: A single step catalytic process for the preparation of aromatic rich aviation fuel from renewable resource in the presence of a hydrogen stream, and one or more hydroprocessing catalysts, under operating conditions for hydroconversion reactions, as defined herein, with mixed hot and cold streams of the renewable feed and getting desired product after separation of water, lighter hydrocarbon gases and carbon oxides, the said product comprising of hydrocarbons C6-C24, rich in aromatic content in the aviation fuel range, including kerosene range.

Abstract: In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes.

Abstract: In various embodiments deformable nano-scale vehicles (DNV) are provided that are useful for the delivery of therapeutic agents. In certain embodiments the DNVs are capable of transdermal delivery and can additionally cross the blood-brain barrier.

Abstract: A single step catalytic process for the preparation of aromatic rich aviation fuel from renewable resource in the presence of a hydrogen stream, and one or more hydroprocessing catalysts, under operating conditions for hydroconversion reactions, as defined herein, with mixed hot and cold streams of the renewable feed and getting desired product after separation of water, lighter hydrocarbon gases and carbon oxides, the said product comprising of hydrocarbons C6-C24, rich in aromatic content in the aviation fuel range, including kerosene range.

Abstract: A novel pt/pd sodalite caged catalyst combination with sulfided base metal catalyst for improved catalytic hydroprocessing of renewable feedstock. Particularly, the invention relates to a process for preparation of the said catalyst. More particularly, the invention relates to a process for the preparation of hydrocarbon fuel from the feed stock using a said catalyst. Further, the invention discloses a novel catalyst and a process for the preparation of the Pt/Pd encapsulated in sodalite cage with silica-alumina ZSM-5 synthesized around it supported with nickel, molybdenum, cobalt, tungsten or one or more thereof. The invention also provides process to convert vegetable oils, free fatty acids, and microbial lipids, bio-crude and conventional non-renewable crude based feed stocks such as diesel, naphtha, kerosene, gas oil, residue, etc.