Patents by Inventor Pascal Berthelot

Pascal Berthelot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 7947852
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: May 24, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20100168244
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: July 1, 2008
    Publication date: July 1, 2010
    Applicant: LESS LABORATOIRES SERVIER
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20100137446
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, R2 represents a fluorine atom or an alkyl group substituted by one or more fluorine atoms. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: July 1, 2008
    Publication date: June 3, 2010
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Heterocyclic Cycloalkyl Compounds, a Process for their Preparation and Pharmaceutical Compositions Containing Them
    Publication number: 20090239917
    Abstract: Compounds of formula (I): wherein: R1 represents a (C3-C8)cycloalkyl group, R2 represents a group of formula (II) as defined in the description, X represents an oxygen atom or an N—OR? group wherein R? represents a hydrogen atom, a linear or branched (C1-C6)alkyl group, an aryl group or an aryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched. Medicinal products containing the same which are useful as hypoglycaemic and hypolipaemic agents.
    Type: Application
    Filed: March 5, 2007
    Publication date: September 24, 2009
    Applicant: Les Laboratoires Servier
    Inventors: Aurelie Hurtevent, Jean-Martial L'Helgoual'ch, Pascal Carato, Nicolas Lebegue, Veronique Leclerc, Morgan Le Naour, Pascal Berthelot, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • Naphthalene compounds
    Patent number: 7462741
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: December 9, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Naphthalene compounds
    Patent number: 7435850
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: October 14, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them.
    Publication number: 20080113974
    Abstract: Compounds of formula (I): wherein: X represents an oxygen atom or a sulphur atom, R1, R2, R3 and R4 are as defined in the description, A represents an alkylene chain as defined in the description, and B represents an alkyl or alkenyl group substituted by a group or R7, or B represents a group or R7.
    Type: Application
    Filed: January 26, 2006
    Publication date: May 15, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Aurelie Hurtevent, Jean-Martial L' Helgoual' Ch, Pascal Carato, Nicolas Lebegue, Veronique Leclerc, Pascal Berthelot, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • Naphthalene compounds
    Publication number: 20080004350
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Naphthalene compounds
    Publication number: 20080004349
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Naphthalene compounds
    Publication number: 20080004348
    Abstract: A compound selected from those of formula (I): wherein: R1 represents a group R4 or NHR4, wherein R4 is as defined in the description; R2 represents a substituted linear or branched (C1-C6)alkyl group; R3 represents a hydrogen or halogen atom or a linear or branched (C1-C6)alkyl or linear or branched (C2-C6)alkenyl group. Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Matthieu Desroses, Jean-Albert Boutin, Valerie Audinot
  • Association between a heterocyclic compound and an antioxidant agent
    Publication number: 20070167502
    Abstract: A pharmaceutical composition for treatment of obesity associated with lipid and carbohydrate metabolism comprising (i) a substance which is useful in promoting lipid and carbohydrate metabolism, (ii) an antioxidant agent and, optionally, (iii) a pharmaceutically acceptable carrier or excipient, wherein the substance which promotes lipid and carbohydrate metabolism and the antioxidant agent are present in therapeutically effective dosages. Methods which are useful in treating conditions associated with obesity.
    Type: Application
    Filed: March 30, 2005
    Publication date: July 19, 2007
    Inventors: Louis Casteilla, Luc Penicaud, Pascal Berthelot, Catherine Dacquet, Daniel-Henri Caignard
  • Heterocyclic oxime compounds
    Patent number: 7071221
    Abstract: Compounds of formula (I): wherein: X represents oxygen or sulphur or a group CH2 or R1, R2, R3, R4, R5 and R6 are as defined in the description, A represents an alkylene chain as defined in the description, B represents alkyl or alkenyl substituted by a group ?or R9, or B represents a group ?or R9, D represents a benzene, pyridine, pyrazine, pyrimidine or pyridazine nucleus.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: July 4, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Véronique Leclerc, Sylvie Pailloux, Pascal Carato, Carine Introvigne, Nicolas Lebegue, Pascal Berthelot, Catherine Dacquet, Jean Albert Boutin, Daniel Henri Caignard, Pierre Renard
  • Novel tricyclic azepine derivatives, method for production thereof and pharmaceutical compositions comprising the same
    Publication number: 20060079677
    Abstract: A compound of formula (I): wherein: represents benzo or pyrido, optionally fused in the 2-3, 3-4 or 4-5 position to a phenyl, (C4-C8)cycloalkyl or heterocyclic group, which may be optionally substituted, W represents X—Y or Y—X, wherein: X represents and Y represents oxygen or N—R3, n represents zero or an integer from 1 to 6, G, R1, R2 and R3 are as defined in the description, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful for the treatment of cancerous diseases.
    Type: Application
    Filed: February 3, 2004
    Publication date: April 13, 2006
    Inventors: Sebastien Gallet, Pascal Berthelot, Nicolas Lebegue, Nathalie Flouquet, Pascal Carato, John Hickman, Alain Pierre, Bruno Pfeiffer, Pierre Renard
  • New heterocyclic oxime compounds
    Publication number: 20050026973
    Abstract: Compounds of formula (I): wherein: X represents oxygen or sulphur or a group CH2 or R1, R2, R3, R4, R5 and R6 are as defined in the description, A represents an alkylene chain as defined in the description, B represents alkyl or alkenyl substituted by a group ?or R9, or B represents a group ?or R9, D represents a benzene, pyridine, pyrazine, pyrimidine or pyridazine nucleus.
    Type: Application
    Filed: July 29, 2004
    Publication date: February 3, 2005
    Inventors: Veronique Leclerc, Sylvie Pailloux, Pascal Carato, Carine Introvigne, Nicolas Lebegue, Pascal Berthelot, Catherine Dacquet, Jean Boutin, Daniel Caignard, Pierre Renard
  • 4-amino-3-heteroaryl butyric acid compounds, compositions, and their use for treating disorders involving a dysfunction of GABA.sub.B receptors
    Patent number: 5278166
    Abstract: A compound of formula (I): ##STR1## and medicinal products containing the same which are useful in treating disorders connected to a dysfunction of GABA.sub.B receptors, are disclosed.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: January 11, 1994
    Assignee: Adir et Compagnie
    Inventors: Michel Debaert, Pascal Berthelot, Claude Vaccher
  • 4-aminobutyric acid compounds, compositions and methods of use for treating disorders related to a dysfunction of GABA.sub.B receptors
    Patent number: 5214063
    Abstract: A compound of formula (I): ##STR1## in which R, R.sub.1 and R.sub.2 are as defined in the description. Medicinal product, which is useful in treating disorders related to a dysfunction of GABA.sub.B receptors.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: May 25, 1993
    Assignee: Adir et Compagnie
    Inventors: Michel Debaert, Pascal Berthelot, Claude Vaccher
  • 4-aminobutyric acid compounds, compositions, and method of use for treating disorders related to a dysfunction of GABA.sub.B receptors
    Patent number: 5162364
    Abstract: A compound of formula (I): ##STR1## in which R, R.sub.1 and R.sub.2 are as defined in the description. Medicinal product, which is useful in treating disorders related to a dysfunction of GABA.sub.B receptors.
    Type: Grant
    Filed: June 11, 1991
    Date of Patent: November 10, 1992
    Assignee: Adir et Compagnie
    Inventors: Michel Debaert, Pascal Berthelot, Claude Vaccher