Patents by Inventor Pascal Delepine

Pascal Delepine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8088747
    Abstract: The invention relates to a compound of general formula (I): where X=0 or 1, Z=O, S or CH2, R1 and R2 independently=OH or OY, where Y=a protecting group, OR3, where R3=a monosaccharide or disaccharide group, A1-CH2—N+(CH3)3, X?, where X=halogen, A1=an amide (NHC(O)) or ester (OC(C)) bond, OPO(OM)2, where M=an alkyli or alkyli earth metal, OP(O)O?—O(CH2)2—N+(CH3)3, A2-(PEGX1-A3)n-R4, where n=0 or 1, PEGX1=a polyethyleneglycol of molecular weight X1, where X1 being less than or equal to 5,000 daltons, A2 and A3 independently=a ether (O), ester (OC(O)), amide (NHC(O)), urea (NHC(O)NH), thiourea (NHC(S)NH), or thioether (S) bond R4=a directing agent.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: January 3, 2012
    Assignees: Ecole Nationale Superieure de Chime de Rennes, Universite de Bretagne Occidentale
    Inventors: Thierry Benvegnu, Daniel Plusquellec, Gildas Rethore, Mickaelle Scahet, Claude Ferec, Tristan Montier, Pascal Delepine, Pierre Lehn
  • Patent number: 7667070
    Abstract: The present invention has for an object a cationic lipophilic compound of the following general formula (I): wherein: a) R1 and R?1 each represent, independently from one another, an alkyl chain, an alkenyl chain or a polyalkenyl chain with from 10 to 24 carbon atoms, with the polyalkenyl chain having from 2 to 4 double links; b) R2 is a hydrogen atom or an alkyl chain having from 1 to 4 carbon atoms; and R3 is a group with the following formula (IIa) —(CH2)n— or following formula (IIb) —C(?NH)—NH—(CH2)n— wherein: n is an integer equal to 0, 1, 2, 3 or 4; and d) A+ is an organic cation; e) X? is an anion.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: February 23, 2010
    Assignees: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante de de la Recherche Medicale (INSERM), Universite de Bretagne Occidentale, Centre Hospitalier Universitaire de Brest
    Inventors: Hervé Des Abbayes, Jean-Jacques Yaouanc, Jean-Claude Clement, Karine Le Ny, Claude Ferec, Tristan Montier, Pascal Delepine
  • Publication number: 20090232880
    Abstract: The invention relates to a compound of general formula (I): where =0 or 1, Z=O, S or CH1-2, R1 and R2 independently=OH or OY, where Y=a protecting group, OR3, where R3=a monosaccharide or disaccharide group, A1-CH2—N+(CH3)3, X?, where X=halogen, A1=an amide (NHC(O)) or ester (OC(O)) bond, OPO(OM)2, where M=an alkali or alkali earth metal, OP(O)O?—O(CH2)2—N+(CH3)3, A2-(PEGX1-A3)n-R4, where n=0 or 1, PEGx1=a polyethyleneglycol of molecular weight X1, where X1, ??5,000 daltons, A2 and A3 independently=a ether (O), ester (OC(O)), amide (NHC((O)), urea (NHC(O)NH), thiourea (NHC(S)NH), or thioether (S) bond and R4=a directing agent.
    Type: Application
    Filed: December 7, 2005
    Publication date: September 17, 2009
    Inventors: Thierry Benvegnu, Daniel Plusquellec, Gildas Rethore, Mickaelle Scahet, Claude Ferec, Tristan Montier, Pascal Delepine, Pierre Lehn
  • Publication number: 20060165768
    Abstract: The present invention has for an object a cationic lipophilic compound of the following general formula (I): wherein: a) R1 and R?1 each represent, independently from one another, an alkyl chain, an alkenyl chain or a polyalkenyl chain with from 10 to 24 carbon atoms, with the polyalkenyl chain having from 2 to 4 double links; b) R2 is a hydrogen atom or an alkyl chain having from 1 to 4 carbon atoms; and R3 is a group with the following formula (IIa) —(CH2)n— or following formula (IIb) —C(?NH)—NH—(CH2)n— wherein: n is an integer equal to 0, 1, 2, 3 or 4; and d) A+ is an organic cation; e) X? is an anion.
    Type: Application
    Filed: November 7, 2003
    Publication date: July 27, 2006
    Applicants: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche, Universite de Bretagne Occidentale, Centre Hospitalier Universitaire de Brest
    Inventors: Harve Des Abbayes, Jean-Jacques Yaouanc, Jean-Claude Clement, Karine Ny, Claude Ferec, Tristan Montier, Pascal Delepine