Patents by Inventor Pascal Delmas

Pascal Delmas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050214378
    Abstract: The present invention relates to stealth lipid nanocapsules comprising an essentially lipid core which is liquid or semi-liquid at ambient temperature, and an outer lipid envelope comprising at least one hydrophilic surfactant which is lipidic in nature, at least one lipophilic surfactant which is lipidic in nature and at least one amphiphilic derivative of poly(ethylene glycol), the molar mass of the poly(ethylene glycol) component of which is greater than or equal to 1000 g/mol, preferably greater than or equal to 2000 g/mol, to the methods for the preparation thereof and to the use thereof as a carrier for active principle(s).
    Type: Application
    Filed: June 11, 2003
    Publication date: September 29, 2005
    Applicant: ETHYPHARM
    Inventors: Didier Hoarau, Pascal Delmas, Jean-Christophe Delmas
  • Publication number: 20040265380
    Abstract: The invention relates to an orodispersible effervescent tablet comprising at least one active ingredient, a mixture of excipients comprising at least one disintegrating agent, a diluting soluble agent, a luficating agent and, optionally, an internal dehydrating agent, a swelling agent, a permeabilizing agent, sweetening agents, flavouring agents and colorants, and effervescent granules based on a mixture which is essentially composed of an acidic agent, a heat extrudable binding agent and an alkaline agent and, optionally, a dehydrating agent and a lubricant, said granules being prepared by means of heat extrusion in the absence of of water and solvents, and said tablet disintegrating in the pharynx when it comes into contact with saliva in at least 60 seconds and preferentially in less than 40 seconds.
    Type: Application
    Filed: August 30, 2004
    Publication date: December 30, 2004
    Inventors: Pascal Delmas, Jean-Marc Zuccarelli, Claire Mallard, James W. McGinity
  • Publication number: 20040076683
    Abstract: The present invention relates to stealth lipid nanocapsules consisting of an essentially lipid core which is liquid or semi-liquid at ambient temperature, and an outer lipid envelope comprising at least one hydrophilic surfactant which is lipidic in nature, at least one lipophilic surfactant which is lipidic in nature and at least one amphiphilic derivative of poly(ethylene glycol), the molar mass of the poly(ethylene glycol) component of which is greater than or equal to 1 000 g/mol, preferably greater than or equal to 2 000 g/mol, to the methods for the preparation thereof and to the use thereof as a carrier for active principle(s).
    Type: Application
    Filed: June 11, 2003
    Publication date: April 22, 2004
    Applicant: ETHYPHARM
    Inventors: Didier Hoarau, Pascal Delmas, Jean-Christophe Leroux
  • Patent number: 6649186
    Abstract: Disclosed here are effervescent granules having a controllable rate of effervescence. In some embodiments, the such granules comprise an acidic agent, an alkaline agent, a pharmacologically active agent, hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process. The present invention also provides a thermal heat process for preparing a pharmacologically active agent containing effervescent granule. In certain aspects, the granules contain pharmacologically active agents such as narcotics, antidiarrheal agents, antiviral agents, anxiolytic agents, a cholesterol lowering agent, an alpha adrenergic blocking agent, a phenanthrene derivative. By way of example, some of the narcotics that may be included in the granules and in the process of preparing the granules include, by way of example: phenanthrene derivatives (e.g., morphine sulfate), and morphine derivatives (e.g.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: November 18, 2003
    Assignee: Ethypharm
    Inventors: Joseph R. Robinson, James William McGinity, Pascal Delmas