Patents by Inventor Pascal Desmazeau

Pascal Desmazeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazole derivatives, preparation thereof, and therapeutic use thereof
    Patent number: 8367715
    Abstract: The invention relates to pyrazole derivatives of general formula (I): in which X represents chlorine or fluorine; to a process for preparing said derivatives, and to therapeutic uses of said derivatives.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: February 5, 2013
    Assignee: Sanofi
    Inventors: Pierre Yves Abecassis, Pascal Desmazeau, Michel Tabart
  • Pyrazole Derivatives, Preparation Thereof, and Therapeutic Use Thereof
    Publication number: 20120270918
    Abstract: The invention relates to pyrazole derivatives of general formula (I): in which X represents chlorine or fluorine; to a process for preparing said derivatives, and to therapeutic uses of said derivatives.
    Type: Application
    Filed: December 23, 2011
    Publication date: October 25, 2012
    Applicant: Sanofi
    Inventors: Pierre Yves ABECASSIS, Pascal DESMAZEAU, Michel TABART
  • Substituted pyrrolopyridines, compositions containing them, manufacturing process therefor and use thereof
    Patent number: 7947706
    Abstract: The invention relates to compounds of formula (I): wherein Ra, R1, Ar, L, A, W, Y, and Z are as defined in the disclosure; to compositions containing them; and to the preparation and use thereof, in particular as anticancer agents.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: May 24, 2011
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michel Tabart, Eric Bacque, Frank Halley, Baptiste Ronan, Pascal Desmazeau, Fabrice Viviani, Catherine Souaille
  • 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them
    Patent number: 7638521
    Abstract: The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: December 29, 2009
    Assignee: sanofi-aventis Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Jean-Christophe Carry, Pascal Desmazeau, Serge Mignani, Jean Bouquerel, Arielle Genevois-Borella, Baptiste Ronan
  • Substituted pyrroles, compositions containing same, method for making same and use thereof
    Patent number: 7592365
    Abstract: The disclosure concerns substituted pyrroles of formula (I): wherein A, L, Ar, R1, R2, R5, and Ra are as defined in the disclosure, compositions containing the same, methods for making the same and uses thereof, in particular as anti-cancer agents.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: September 22, 2009
    Assignee: Aventis Pharma S.A.
    Inventors: Baptiste Ronan, Michel Tabart, Catherine Souaille, Fabrice Viviani, Eric Bacque, Jean-Philippe Letallec, Pascal Desmazeau
  • 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them
    Patent number: 7531663
    Abstract: The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: May 12, 2009
    Assignee: sanofi-aventis Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Jean-Christophe Carry, Pascal Desmazeau, Serge Mignani, Jean Bouquerel, Arielle Genevois-Borella, Baptiste Ronan
  • Substituted indazoles, compositions containing the same, and the preparation and use thereof
    Patent number: 7517902
    Abstract: Disclosed are novel substituted indazole compounds, pharmaceutical compositions comprising such compounds, and methods of treatment comprising such compounds.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: April 14, 2009
    Assignee: Aventis Pharma S.A.
    Inventors: Frank Halley, Michel Tabart, Hervé Bouchard, Catherine Souaille, Alain Le Brun, Fabrice Viviani, Laurence Gauzy-Lazo, Pascal Desmazeau, Odile Angouillant-Boniface, Bruno Filoche-Romme
  • Substituted Pyrroles, Compositions Containing Same, Method for Making Same and Use Thereof
    Publication number: 20080167368
    Abstract: The disclosure concerns substituted pyrroles of formula (I): wherein A, L, Ar, R1, R2, R5, and Ra are as defined in the disclosure, compositions containing the same, methods for making the same and uses thereof, in particular as anti-cancer agents.
    Type: Application
    Filed: August 1, 2007
    Publication date: July 10, 2008
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Baptiste RONAN, Michel TABART, Catherine SOUAILLE, Fabrice VIVIANI, Eric BACQUE, Jean-Philippe LETALLEC, Pascal DESMAZEAU
  • Substituted Pyrrolopyridines, Compositions Containing Them, Manufacturing Process Therefor and Use Thereof
    Publication number: 20080139606
    Abstract: The invention relates to compounds of formula (I): wherein Ra, R1, Ar, L, A, W, Y, and Z are as defined in the disclosure; to compositions containing them; and to the preparation and use thereof, in particular as anticancer agents.
    Type: Application
    Filed: October 11, 2007
    Publication date: June 12, 2008
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Michel Tabart, Eric Bacque, Frank Halley, Baptiste Ronan, Pascal Desmazeau, Fabrice Viviani, Catherine Souaille
  • Substituted Indazoles, Compositions Containing The Same, And The Preparation And Use Thereof
    Publication number: 20070161626
    Abstract: Disclosed are novel substituted indazole compounds, pharmaceutical compositions comprising such compounds, and methods of treatment comprising such compounds.
    Type: Application
    Filed: December 4, 2006
    Publication date: July 12, 2007
    Applicant: Aventis Pharma S.A.
    Inventors: Frank Halley, Michel Tabart, Herve Bouchard, Catherine Souaille, Alain Le Brun, Fabrice Viviani, Laurence Gauzy-Lazo, Pascal Desmazeau, Odile Angouillant-Boniface, Bruno Filoche-Romme
  • Streptogramin derivatives and compositions thereof
    Patent number: 7232799
    Abstract: The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B streptogramin derivative
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: June 19, 2007
    Assignee: Aventis Pharma SA
    Inventors: Pascal Desmazeau, Baptiste Ronan, Eric Bacque, Jean-Claude Barriere
  • Derivatives of 3-(Guanidinocarbonyl) heterocycle, methods of preparation and intermediates thereof, their use as medicaments, and pharmaceutical compositions therefrom
    Patent number: 7230007
    Abstract: The present invention discloses and claims compounds of formula I and their pharmaceutically acceptable salts, and methods of using said compounds of formula I, either alone or in combination with other medicaments, as antiarrhythmic medicaments with a cardioprotective component for prophylaxis or treatment of infarction, for the treatment of angina pectoris, and as inhibitors of pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure. Pharmaceutical compositions comprising compounds of formula I or compounds of formula I in combination with one or more other medicaments and processes for the preparation of compounds of formula I are also disclosed and claimed.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: June 12, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Jean-Christophe Carry, Gilles Doerflinger, Arielle Genevois-Borella, Michel Evers, Alain Le Brun, Jean-Paul Martin, Pascal Desmazeau, Serge Mignani, Heinz-Werner Kleemann
  • Streptogramin derivatives, their preparation and compositions containing them
    Patent number: 7166594
    Abstract: Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond --- represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: January 23, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
  • Derivatives of 3-guanidinocarbonyl-1-heteroaryl-pyrrole, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them
    Patent number: 7078414
    Abstract: The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-pyrrole derivatives of formula (I) wherein R1 to R3 and Ar are as defined herein, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: July 18, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Pascal Desmazeau, Jean-Christophe Carry, Baptiste Ronan, Serge Mignani, Jean Bououerel, Arielle Genevois-Borella
  • Streptogramin derivatives, preparation method and compositions containing same
    Patent number: 7019110
    Abstract: Group B streptogramin derivatives of general formula (I) are disclosed: wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing the same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: March 28, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gérard Puchault
  • Streptogramin derivatives and compositions thereof
    Publication number: 20050267181
    Abstract: The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B streptogramin derivative.
    Type: Application
    Filed: July 29, 2005
    Publication date: December 1, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Pascal Desmazeau, Baptiste Ronan, Eric Bacque, Jean-Claude Barriere
  • Streptogramin derivatives, their preparation and compositions which contain them
    Patent number: 6962901
    Abstract: Group A streptogramin derivatives of formula (I) and salts thereof: and Group A streptogramin derivatives of formula (III) and salts thereof: as well as processes for preparing such streptogramins, and pharmaceutical compositions comprising such streptogramins, alone or combined with at least one group B streptogramin derivative.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: November 8, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Pascal Desmazeau, Baptisite Ronan, Eric Bacque, Jean-Claude Barriere
  • Streptogramin derivatives, preparation method and compositions containing same
    Patent number: 6958383
    Abstract: Group B streptogramin derivatives of general formula (I): wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: October 25, 2005
    Assignee: Aventis Pharma S. A.
    Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gérard Puchault
  • 3-Guanidinocarbonyl-1-heteroaryl-indole derivatives, preparation process, their use as medicaments, and pharmaceutical compositions comprising them
    Publication number: 20050026989
    Abstract: The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation.
    Type: Application
    Filed: December 31, 2003
    Publication date: February 3, 2005
    Applicant: AVENTIS PHARMA DEUTSCHLAND GmbH
    Inventors: Heinz-Werner Kleemann, Jean-Christophe Carry, Pascal Desmazeau, Serge Mignani, Jean Bouquerel, Arielle Genevois-Borella, Baptiste Ronan
  • Derivatives of 3-(guanidinocarbonyl) heterocycle, methods of preparation and intermediates thereof, their use as medicaments, and pharmaceutical compositions therefrom
    Publication number: 20050014758
    Abstract: The present invention discloses and claims compounds of formula I and their pharmaceutically acceptable salts, and methods of using said compounds of formula I, either alone or in combination with other medicaments, as antiarrhythmic medicaments with a cardioprotective component for prophylaxis or treatment of infarction, for the treatment of angina pectoris, and as inhibitors of pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure. Pharmaceutical compositions comprising compounds of formula I or compounds of formula I in combination with one or more other medicaments and processes for the preparation of compounds of formula I are also disclosed and claimed.
    Type: Application
    Filed: June 10, 2004
    Publication date: January 20, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jean-Christophe Carry, Gilles Doerflinger, Arielle Genevois-Borella, Michel Evers, Alain Le Brun, Jean-Paul Martin, Pascal Desmazeau, Serge Mignani, Heinz-Werner Kleemann