Patents by Inventor Pascal Espie

Pascal Espie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH AN ANTI-TL1A ANTIBODY
    Publication number: 20250376530
    Abstract: The present disclosure provides methods and compositions for treating inflammatory bowel disease (IBD), e.g., ulcerative colitis (UC) or Crohn's disease (CD), with a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody.
    Type: Application
    Filed: May 16, 2025
    Publication date: December 11, 2025
    Inventors: Akiko CHAI, Karen LASCH, Kun Tae PARK, Daniela BOJIC, Pascal ESPIE
  • Anti-CD40 antibodies for use in treatment of hidradenitis suppurativa
    Patent number: 12435150
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating hidradenitis suppurativa, by employing CD40 antagonists, such as anti-CD40 antibodies.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: October 7, 2025
    Assignee: NOVARTIS AG
    Inventors: Pascal Espie, Christian Loesche, Lukas Roth, James Rush, Grazyna Wieczorek
  • Anti-CD40 Antibodies for Use in Treatment of Sjogren's Syndrome
    Publication number: 20250206833
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating Sjögren's syndrome, by employing anti-CD40 antibodies.
    Type: Application
    Filed: July 26, 2024
    Publication date: June 26, 2025
    Inventors: Pascal ESPIE, Peter GERGELY, James RUSH
  • ANTI-CD40 ANTIBODIES FOR USE IN PREVENTION OF GRAFT REJECTION
    Publication number: 20240287198
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for preventing graft rejection in solid organ transplantation, by employing anti-CD40 antibodies.
    Type: Application
    Filed: September 1, 2023
    Publication date: August 29, 2024
    Inventors: Pascal ESPIE, Boerje HARALDSSON, James RUSH
  • Anti-CD40 antibodies for use in treatment of Sjögren's syndrome
    Patent number: 12065499
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating Sjögren's syndrome, by employing anti-CD40 antibodies.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: August 20, 2024
    Assignee: Novartis AG
    Inventors: Pascal Espie, Peter Gergely, James Rush
  • Anti-CD40 antibodies for use in prevention of graft rejection
    Patent number: 11780927
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for preventing graft rejection in solid organ transplantation, by employing anti-CD40 antibodies.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: October 10, 2023
    Assignee: NOVARTIS AG
    Inventors: Pascal Espie, Boerje Haraldsson, James Rush
  • ANTI-CD40 ANTIBODIES FOR USE IN TREATMENT OF TIDM AND INSULITIS
    Publication number: 20220195061
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating T1DM, by employing anti-CD40 antibodies.
    Type: Application
    Filed: May 6, 2020
    Publication date: June 23, 2022
    Inventors: Pascal ESPIE, Allison GOLDFINE, Rainer MUSSMANN, James RUSH
  • ANTI-CD40 ANTIBODIES FOR USE IN TREATMENT OF HIDRADENITIS
    Publication number: 20220098315
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating hidradenitis suppurativa, by employing CD40 antagonists, such as anti-CD40 antibodies.
    Type: Application
    Filed: January 9, 2020
    Publication date: March 31, 2022
    Inventors: Pascal ESPIE, Christian LOESCHE, Lukas ROTH, James RUSH, Grazyna WIECZOREK
  • ANTI-CD40 ANTIBODIES FOR USE IN PREVENTION OF GRAFT REJECTION
    Publication number: 20210079107
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for preventing graft rejection in solid organ transplantation, by employing anti-CD40 antibodies.
    Type: Application
    Filed: April 11, 2019
    Publication date: March 18, 2021
    Inventors: Pascal ESPIE, Boerje HARALDSSON, James RUSH
  • Anti-CD40 Antibodies for Use in Treatment of Sjogren's Syndrome
    Publication number: 20190153111
    Abstract: The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating Sjögren's syndrome, by employing anti-CD40 antibodies.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 23, 2019
    Inventors: Pascal Espie, Peter Gergely, James Rush