Patents by Inventor Pascal Hols

Pascal Hols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND STRAIN
    Publication number: 20230332183
    Abstract: The present invention relates to a method for transforming a strain of the Lactococcus genus through natural competence. The present invention further relates to strains obtained or obtainable by said method. The present invention also relates to a method for identifying a strain of the Lactococcus genus which is transformable through natural competence.
    Type: Application
    Filed: February 22, 2023
    Publication date: October 19, 2023
    Inventors: Christophe Fremaux, Philippe Horvath, Patrick Boyaval, Pascal Hols, David Blandine, Amandine Radziejwoski, Laetitia Fontaine, Frederic Toussaint
  • PEPTIDES FOR INDUCING BACTERIOCIN SYNTHESIS AND METHODS TO IDENTIFY AND/OR SELECT AND/OR OPTIMIZE THE SAME
    Publication number: 20220017573
    Abstract: Described herein is a peptide or peptidomimetic with a length of at least 6 residues comprising, consisting essentially of, or consisting of the sequence motif Xaa1-Trp-Xaa2-Xaa3-Xaa4-Xaa5 (SEQ ID NO:1), wherein: Xaa1 represents an aromatic residue (Phe, Tyr, Trp, His), Cys or Ser; Xaa2, Xaa3 and Xaa4 represent any residue; and Xaa5 represents Gly, lie or Val.
    Type: Application
    Filed: November 22, 2019
    Publication date: January 20, 2022
    Inventors: Johann Mignolet, Pascal Hols, Laura Ledesma García
  • METHODS AND STRAIN
    Publication number: 20200087686
    Abstract: The present invention relates to a method for transforming a strain of the Lactococcus genus through natural competence. The present invention further relates to strains obtained or obtainable by said method. The present invention also relates to a method for identifying a strain of the Lactococcus genus which is transformable through natural competence.
    Type: Application
    Filed: December 19, 2017
    Publication date: March 19, 2020
    Inventors: Christophe Fremaux, Philippe Horvath, Patrick Boyaval, Pascal Hols, David Blandine, Amandine Radziejwoski, Laetitia Fontaine, Frederic Toussaint
  • Method for transforming a bacterium belonging to the genus by natural competence
    Patent number: 9243254
    Abstract: The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: January 26, 2016
    Assignee: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Patrick Boyaval, Christophe Fremaux, Pascal Hols, Laetitia Fontaine, Philippe Horvath
  • METHOD FOR TRANSFORMING A BACTERIUM BELONGING TO THE STREPTOCOCCUS GENUS BY NATURAL COMPETENCE
    Publication number: 20140134295
    Abstract: The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.
    Type: Application
    Filed: January 23, 2014
    Publication date: May 15, 2014
    Inventors: Patrick Boyaval, Christophe Fremaux, Pascal Hols, Laetitia Fontaine, Philippe Horvath
  • Method for transforming a bacterium belonging to the genus by natural competence
    Patent number: 8663655
    Abstract: The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: March 4, 2014
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Patrick Boyaval, Christophe Fremaux, Pascal Hols, Laetitia Fontaine, Philippe Horvath
  • Method for Transforming a Bacterium Belonging to the Streptococcus Genus by Natural Competence
    Publication number: 20120129264
    Abstract: The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the Streptococcus genus by natural competence and their use in the food and feed industry.
    Type: Application
    Filed: June 23, 2010
    Publication date: May 24, 2012
    Applicant: DANISCO A/S
    Inventors: Patrick Boyaval, Christophe Fremaux, Pascal Hols, Laetitia Fontaine, Philippe Horvath
  • Process for the production of alanine by recombinant microorganisms
    Patent number: 6627420
    Abstract: A process for preparing alanine by culturing a genetically modified microorganism that produces alanine from glucose. The microorganism is one that has been modified to result in an overexpression of an endogenous alanine dehydrogenase gene, expression of a heterologous alanine dehydrogenase gene, or a combination of both. The source of alanine dehydrogenase may be Bacillus sphaericus. The modified microorganisms may be a homofermentative microorganism, such as a strain of L. lactis. The process can be used for in situ and stereoscopic preparation of alanine. The invention also relates to the microorganisms and the recombinant DNA molecules that can be used in the invention, as well as to alanine and alanine-containing products obtained according to the process of the invention.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: September 30, 2003
    Assignee: Nederlands Instituut voor Zuivelonderzoek
    Inventors: Pascal Hols, Michiel Kleerebezem, Oscar Paul Kuipers, Thierry Ferain, Jean Marcelin Alain Marie Ghislain Delcour, Willem Meindert De Vos